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Compile Data Set for Download or QSAR

Found 128 hits of kd data for polymerid = 4967   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50073748
PNG
(CHEMBL3559508)
Show SMILES CC(=O)N[C@H]1[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS(O)(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](COS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1OS(O)(=O)=O)C(O)=O
Show InChI InChI=1/C48H74N4O40S6/c1-17(53)50-27-37(31(60)24(15-82-95(69,70)71)84-45(27)81-14-23(56)30(59)29(58)22(55)13-49-19-6-5-7-20(12-19)52-26(57)9-4-3-8-21-10-11-93-94-21)86-48-41(92-98(78,79)80)35(64)39(42(90-48)44(67)68)88-46-28(51-18(2)54)38(87-47-34(63)32(61)33(62)40(89-47)43(65)66)36(91-97(75,76)77)25(85-46)16-83-96(72,73)74/h5-7,12,21-25,27-42,45-49,55-56,58-64H,3-4,8-11,13-16H2,1-2H3,(H,50,53)(H,51,54)(H,52,57)(H,65,66)(H,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/t21?,22-,23+,24+,25+,27+,28+,29+,30+,31-,32-,33-,34+,35-,36-,37+,38+,39-,40-,41+,42-,45+,46-,47+,48+/s2
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n/an/an/a 4.70n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method


Bioorg Med Chem Lett 25: 1552-5 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063776
PNG
(CHEMBL3397498)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O29S6.5Na/c1-15(38)36-23-28(62-34-31(66-72(56,57)58)29(65-71(53,54)55)26(44)30(63-34)32(45)46)27(64-70(50,51)52)21(14-60-69(47,48)49)61-33(23)59-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-67-68-18;;;;;/h4-6,11,18-21,23-31,33-35,39-40,42-44H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58);;;;;/q;5*+1/p-5/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29-,30-,31+,33-,34+;;;;;/s2
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n/an/an/a 4.90n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50073747
PNG
(CHEMBL3409457)
Show SMILES CC(=O)N[C@H]1[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1/C48H74N4O40S6/c1-17(53)50-27-38(36(91-97(75,76)77)24(15-82-95(69,70)71)84-45(27)81-14-23(56)30(59)29(58)22(55)13-49-19-6-5-7-20(12-19)52-26(57)9-4-3-8-21-10-11-93-94-21)86-48-35(64)33(62)40(42(90-48)44(67)68)88-46-28(51-18(2)54)39(87-47-34(63)31(60)32(61)41(89-47)43(65)66)37(92-98(78,79)80)25(85-46)16-83-96(72,73)74/h5-7,12,21-25,27-42,45-49,55-56,58-64H,3-4,8-11,13-16H2,1-2H3,(H,50,53)(H,51,54)(H,52,57)(H,65,66)(H,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/p-4/t21?,22-,23+,24+,25+,27+,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38+,39+,40-,41-,42-,45+,46-,47+,48+/s2
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n/an/an/a 5.20n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method


Bioorg Med Chem Lett 25: 1552-5 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50073750
PNG
(CHEMBL3409454)
Show SMILES CC(=O)N[C@H]1[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1/C48H74N4O37S5/c1-17(54)50-27-38(36(88-93(73,74)75)24(14-53)81-45(27)79-15-23(57)30(60)29(59)22(56)13-49-19-6-5-7-20(12-19)52-26(58)9-4-3-8-21-10-11-90-91-21)83-48-35(65)33(63)40(42(87-48)44(68)69)85-46-28(51-18(2)55)39(84-47-34(64)31(61)32(62)41(86-47)43(66)67)37(89-94(76,77)78)25(82-46)16-80-92(70,71)72/h5-7,12,21-25,27-42,45-49,53,56-57,59-65H,3-4,8-11,13-16H2,1-2H3,(H,50,54)(H,51,55)(H,52,58)(H,66,67)(H,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)/p-3/t21?,22-,23+,24+,25+,27+,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38+,39+,40-,41-,42-,45+,46-,47+,48+/s2
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n/an/an/a 5.60n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method


Bioorg Med Chem Lett 25: 1552-5 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50073749
PNG
(CHEMBL3409455)
Show SMILES CC(=O)N[C@H]1[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1/C48H74N4O37S5/c1-17(53)50-27-38(31(60)24(15-80-92(70,71)72)82-45(27)79-14-23(56)30(59)29(58)22(55)13-49-19-6-5-7-20(12-19)52-26(57)9-4-3-8-21-10-11-90-91-21)84-48-36(65)34(63)40(42(88-48)44(68)69)86-46-28(51-18(2)54)39(85-47-35(64)32(61)33(62)41(87-47)43(66)67)37(89-94(76,77)78)25(83-46)16-81-93(73,74)75/h5-7,12,21-25,27-42,45-49,55-56,58-65H,3-4,8-11,13-16H2,1-2H3,(H,50,53)(H,51,54)(H,52,57)(H,66,67)(H,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)/p-3/t21?,22-,23+,24+,25+,27+,28+,29+,30+,31-,32-,33-,34+,35+,36+,37-,38+,39+,40-,41-,42-,45+,46-,47+,48+/s2
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n/an/an/a 8.20n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method


Bioorg Med Chem Lett 25: 1552-5 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50073751
PNG
(CHEMBL3409453)
Show SMILES CC(=O)N[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@H]3[C@@H](NC(C)=O)[C@H](OCC(O)C(O)C(O)C(O)CNc4cccc(NC(=O)CCCCC5CCSS5)c4)O[C@H](COS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)O[C@@H]2C(O)=O)O[C@H](COS([O-])(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1OS([O-])(=O)=O)C(O)=O
Show InChI InChI=1/C48H74N4O43S7/c1-17(53)50-27-36(88-47-40(94-101(77,78)79)33(62)32(61)39(91-47)43(64)65)31(60)24(15-84-98(68,69)70)86-46(27)90-38-34(63)41(95-102(80,81)82)48(92-42(38)44(66)67)89-37-28(51-18(2)54)45(87-25(16-85-99(71,72)73)35(37)93-100(74,75)76)83-14-23(56)30(59)29(58)22(55)13-49-19-6-5-7-20(12-19)52-26(57)9-4-3-8-21-10-11-96-97-21/h5-7,12,21-25,27-42,45-49,55-56,58-63H,3-4,8-11,13-16H2,1-2H3,(H,50,53)(H,51,54)(H,52,57)(H,64,65)(H,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)/p-5/t21?,22?,23?,24-,25-,27-,28-,29?,30?,31+,32+,33+,34+,35+,36-,37-,38+,39+,40-,41-,42+,45-,46+,47-,48-/s2
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n/an/an/a 16n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method


Bioorg Med Chem Lett 25: 1552-5 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063847
PNG
(CHEMBL3397488)
Show SMILES [Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C([O-])=O
Show InChI InChI=1/C34H53N3O23S4.3Na/c1-15(38)36-23-30(58-34-28(46)26(44)27(45)31(59-34)32(47)48)29(60-64(52,53)54)21(14-56-63(49,50)51)57-33(23)55-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-61-62-18;;;/h4-6,11,18-21,23-31,33-35,39-40,42-46H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,47,48)(H,49,50,51)(H,52,53,54);;;/q;3*+1/p-3/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29-,30+,31-,33-,34+;;;/s2
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n/an/an/a 16n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063824
PNG
(CHEMBL3397494)
Show SMILES [Na+].[Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O26S5.4Na/c1-15(38)36-23-29(60-34-31(63-68(54,55)56)27(45)26(44)30(61-34)32(46)47)28(62-67(51,52)53)21(14-58-66(48,49)50)59-33(23)57-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-64-65-18;;;;/h4-6,11,18-21,23-31,33-35,39-40,42-45H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56);;;;/q;4*+1/p-4/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28-,29+,30-,31+,33-,34+;;;;/s2
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n/an/an/a 21n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063843
PNG
(CHEMBL3397491)
Show SMILES [Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O23S4.3Na/c1-15(38)36-23-29(58-34-31(60-64(52,53)54)28(46)27(45)30(59-34)32(47)48)26(44)21(14-56-63(49,50)51)57-33(23)55-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-61-62-18;;;/h4-6,11,18-21,23-31,33-35,39-40,42-46H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,47,48)(H,49,50,51)(H,52,53,54);;;/q;3*+1/p-3/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28-,29+,30-,31+,33-,34+;;;/s2
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n/an/an/a 23n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063848
PNG
(CHEMBL3397487)
Show SMILES [Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1O)C([O-])=O
Show InChI InChI=1/C34H53N3O20S3.2Na/c1-15(39)36-23-29(55-34-28(47)30(57-60(50,51)52)27(46)31(56-34)32(48)49)26(45)21(13-38)54-33(23)53-14-20(41)25(44)24(43)19(40)12-35-16-5-4-6-17(11-16)37-22(42)8-3-2-7-18-9-10-58-59-18;;/h4-6,11,18-21,23-31,33-35,38,40-41,43-47H,2-3,7-10,12-14H2,1H3,(H,36,39)(H,37,42)(H,48,49)(H,50,51,52);;/q;2*+1/p-2/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29+,30-,31-,33-,34+;;/s2
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n/an/an/a 25n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307389
PNG
(2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCCCCCCn2cc(nn2)-c2cccc3ccccc23)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C50H75N3O74S16/c54-128(55,56)103-17-26-31(117-133(69,70)71)36(113-48-43(125-141(93,94)95)37(32(118-134(72,73)74)27(110-48)18-104-129(57,58)59)115-50-45(127-143(99,100)101)40(123-139(87,88)89)35(121-137(81,82)83)30(112-50)21-107-132(66,67)68)42(124-140(90,91)92)47(109-26)114-38-33(119-135(75,76)77)28(19-105-130(60,61)62)111-49(44(38)126-142(96,97)98)116-41-39(122-138(84,85)86)34(120-136(78,79)80)29(20-106-131(63,64)65)108-46(41)102-15-8-4-2-1-3-7-14-53-16-25(51-52-53)24-13-9-11-22-10-5-6-12-23(22)24/h5-6,9-13,16,26-50H,1-4,7-8,14-15,17-21H2,(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)(H,87,88,89)(H,90,91,92)(H,93,94,95)(H,96,97,98)(H,99,100,101)/p-16/t26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36+,37+,38+,39+,40+,41+,42+,43+,44+,45+,46+,47-,48-,49-,50-/m1/s1
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n/an/an/a 35n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063850
PNG
(CHEMBL3397485)
Show SMILES [Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C([O-])=O
Show InChI InChI=1/C34H53N3O20S3.2Na/c1-15(38)36-23-30(56-34-29(47)27(45)28(46)31(57-34)32(48)49)26(44)21(14-54-60(50,51)52)55-33(23)53-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-58-59-18;;/h4-6,11,18-21,23-31,33-35,39-40,42-47H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,48,49)(H,50,51,52);;/q;2*+1/p-2/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28-,29+,30+,31-,33-,34+;;/s2
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n/an/an/a 36n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50388343
PNG
(CHEMBL2059243)
Show SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OCc1cn(CCCO[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]2O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)nn1
Show InChI InChI=1S/C63H107N3O75S16/c1-28(2)8-6-9-29(3)34-12-13-35-33-11-10-30-20-32(14-16-62(30,4)36(33)15-17-63(34,35)5)116-22-31-21-66(65-64-31)18-7-19-115-57-52(50(136-152(97,98)99)45(134-150(91,92)93)40(122-57)26-120-145(76,77)78)130-60-55(140-156(109,110)111)49(44(133-149(88,89)90)39(125-60)25-119-144(73,74)75)128-58-53(138-154(103,104)105)47(42(131-147(82,83)84)37(123-58)23-117-142(67,68)69)127-59-54(139-155(106,107)108)48(43(132-148(85,86)87)38(124-59)24-118-143(70,71)72)129-61-56(141-157(112,113)114)51(137-153(100,101)102)46(135-151(94,95)96)41(126-61)27-121-146(79,80)81/h21,28-30,32-61H,6-20,22-27H2,1-5H3,(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)(H,88,89,90)(H,91,92,93)(H,94,95,96)(H,97,98,99)(H,100,101,102)(H,103,104,105)(H,106,107,108)(H,109,110,111)(H,112,113,114)/p-16/t29-,30+,32+,33+,34-,35+,36+,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58-,59-,60-,61-,62+,63-/m1/s1
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n/an/an/a 39n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF-2 by surface plasmon resonance assay


J Med Chem 55: 3804-13 (2012)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063846
PNG
(CHEMBL3397489)
Show SMILES [Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O23S4.3Na/c1-15(39)36-23-29(57-34-31(60-64(52,53)54)27(46)26(45)30(58-34)32(47)48)28(59-63(49,50)51)21(13-38)56-33(23)55-14-20(41)25(44)24(43)19(40)12-35-16-5-4-6-17(11-16)37-22(42)8-3-2-7-18-9-10-61-62-18;;;/h4-6,11,18-21,23-31,33-35,38,40-41,43-46H,2-3,7-10,12-14H2,1H3,(H,36,39)(H,37,42)(H,47,48)(H,49,50,51)(H,52,53,54);;;/q;3*+1/p-3/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28-,29+,30-,31+,33-,34+;;;/s2
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n/an/an/a 41n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063844
PNG
(CHEMBL3397490)
Show SMILES [Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1O)C([O-])=O
Show InChI InChI=1/C34H53N3O23S4.3Na/c1-15(39)36-23-29(57-34-27(46)30(60-64(52,53)54)26(45)31(58-34)32(47)48)28(59-63(49,50)51)21(13-38)56-33(23)55-14-20(41)25(44)24(43)19(40)12-35-16-5-4-6-17(11-16)37-22(42)8-3-2-7-18-9-10-61-62-18;;;/h4-6,11,18-21,23-31,33-35,38,40-41,43-46H,2-3,7-10,12-14H2,1H3,(H,36,39)(H,37,42)(H,47,48)(H,49,50,51)(H,52,53,54);;;/q;3*+1/p-3/t18?,19-,20+,21+,23+,24+,25+,26-,27+,28-,29+,30-,31-,33-,34+;;;/s2
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n/an/an/a 41n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307387
PNG
(8-(4-Phenyl[1,2,3]triazol-1-yl)octyl 2,3,4,6-Tetra...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](OCCCCCCCCn3cc(nn3)-c3ccccc3)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C46H73N3O74S16/c50-124(51,52)99-15-22-27(113-129(65,66)67)32(109-44-39(121-137(89,90)91)33(28(114-130(68,69)70)23(106-44)16-100-125(53,54)55)111-46-41(123-139(95,96)97)36(119-135(83,84)85)31(117-133(77,78)79)26(108-46)19-103-128(62,63)64)38(120-136(86,87)88)43(105-22)110-34-29(115-131(71,72)73)24(17-101-126(56,57)58)107-45(40(34)122-138(92,93)94)112-37-35(118-134(80,81)82)30(116-132(74,75)76)25(18-102-127(59,60)61)104-42(37)98-13-9-4-2-1-3-8-12-49-14-21(47-48-49)20-10-6-5-7-11-20/h5-7,10-11,14,22-46H,1-4,8-9,12-13,15-19H2,(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)(H,86,87,88)(H,89,90,91)(H,92,93,94)(H,95,96,97)/p-16/t22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32+,33+,34+,35+,36+,37+,38+,39+,40+,41+,42+,43-,44-,45-,46-/m1/s1
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n/an/an/a 43n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50073810
PNG
(CHEMBL3559507)
Show SMILES CC(=O)N[C@H]1[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS(O)(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](COS(O)(=O)=O)[C@H](O)[C@H](O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3OS(O)(=O)=O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1OS(O)(=O)=O)C(O)=O
Show InChI InChI=1/C48H74N4O40S6/c1-17(53)50-27-36(31(60)24(15-82-95(69,70)71)84-45(27)81-14-23(56)30(59)29(58)22(55)13-49-19-6-5-7-20(12-19)52-26(57)9-4-3-8-21-10-11-93-94-21)86-48-41(92-98(78,79)80)35(64)38(42(90-48)44(67)68)88-46-28(51-18(2)54)37(32(61)25(85-46)16-83-96(72,73)74)87-47-40(91-97(75,76)77)34(63)33(62)39(89-47)43(65)66/h5-7,12,21-25,27-42,45-49,55-56,58-64H,3-4,8-11,13-16H2,1-2H3,(H,50,53)(H,51,54)(H,52,57)(H,65,66)(H,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/t21?,22-,23+,24+,25+,27+,28+,29+,30+,31-,32-,33-,34-,35-,36+,37+,38-,39-,40+,41+,42-,45+,46-,47+,48+/s2
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n/an/an/a 48n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor method


Bioorg Med Chem Lett 25: 1552-5 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50388333
PNG
(CHEMBL2059502)
Show SMILES C[C@H](CCC(=O)N[C@@H]1O[C@H](COS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]4OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]3OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](CC[C@]4(C)[C@H]3C[C@H](OC(C)=O)[C@]12C)OS([O-])(=O)=O
Show InChI InChI=1S/C50H83NO66S14/c1-19(24-8-9-25-23-7-6-21-13-22(108-122(66,67)68)11-12-49(21,3)26(23)14-31(50(24,25)4)100-20(2)52)5-10-32(53)51-45-41(114-128(84,85)86)37(110-124(72,73)74)33(27(101-45)15-96-118(54,55)56)105-46-42(115-129(87,88)89)38(111-125(75,76)77)34(28(102-46)16-97-119(57,58)59)106-47-43(116-130(90,91)92)39(112-126(78,79)80)35(29(103-47)17-98-120(60,61)62)107-48-44(117-131(93,94)95)40(113-127(81,82)83)36(109-123(69,70)71)30(104-48)18-99-121(63,64)65/h19,21-31,33-48H,5-18H2,1-4H3,(H,51,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)(H,87,88,89)(H,90,91,92)(H,93,94,95)/p-14/t19-,21+,22+,23+,24-,25+,26+,27-,28-,29-,30-,31+,33-,34-,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45-,46-,47-,48-,49+,50-/m1/s1
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n/an/an/a 50n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF-2 by surface plasmon resonance assay


J Med Chem 55: 3804-13 (2012)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063810
PNG
(CHEMBL3397496)
Show SMILES [Na+].[Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O26S5.4Na/c1-15(39)36-23-28(59-34-31(63-68(54,55)56)29(62-67(51,52)53)26(45)30(60-34)32(46)47)27(61-66(48,49)50)21(13-38)58-33(23)57-14-20(41)25(44)24(43)19(40)12-35-16-5-4-6-17(11-16)37-22(42)8-3-2-7-18-9-10-64-65-18;;;;/h4-6,11,18-21,23-31,33-35,38,40-41,43-45H,2-3,7-10,12-14H2,1H3,(H,36,39)(H,37,42)(H,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56);;;;/q;4*+1/p-4/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29-,30-,31+,33-,34+;;;;/s2
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n/an/an/a 52n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063812
PNG
(CHEMBL3397495)
Show SMILES [Na+].[Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1O)C([O-])=O
Show InChI InChI=1/C34H53N3O26S5.4Na/c1-15(38)36-23-29(60-34-27(45)30(63-68(54,55)56)26(44)31(61-34)32(46)47)28(62-67(51,52)53)21(14-58-66(48,49)50)59-33(23)57-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-64-65-18;;;;/h4-6,11,18-21,23-31,33-35,39-40,42-45H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56);;;;/q;4*+1/p-4/t18?,19-,20+,21+,23+,24+,25+,26-,27+,28-,29+,30-,31-,33-,34+;;;;/s2
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n/an/an/a 60n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50378647
PNG
(CHEMBL1627122 | PI-88)
Show SMILES [O-]P([O-])(=O)OC[C@H]1O[C@H](O[C@H]2[C@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H](O[C@H]3[C@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H](O[C@H]4[C@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H](O[C@@H]5[C@@H](OS([O-])(=O)=O)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@H]4OS([O-])(=O)=O)[C@H]3OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C30H53O77PS16/c31-108(32,33)82-1-6-14(99-116(55,56)57)20(102-119(64,65)66)25(106-123(76,77)78)29(87-6)94-17-12(97-114(49,50)51)8(3-84-110(37,38)39)89-27(23(17)104-121(70,71)72)92-16-11(96-113(46,47)48)7(2-83-109(34,35)36)88-26(22(16)103-120(67,68)69)93-18-13(98-115(52,53)54)9(4-85-111(40,41)42)90-28(24(18)105-122(73,74)75)95-21-19(101-118(61,62)63)15(100-117(58,59)60)10(5-86-112(43,44)45)91-30(21)107-124(79,80)81/h6-30H,1-5H2,(H2,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)/p-18/t6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17+,18+,19+,20+,21+,22+,23+,24+,25+,26-,27-,28-,29-,30-/m1/s1
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n/an/an/a 61n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063849
PNG
(CHEMBL3397486)
Show SMILES [Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O20S3.2Na/c1-15(39)36-23-29(55-34-31(57-60(50,51)52)28(47)27(46)30(56-34)32(48)49)26(45)21(13-38)54-33(23)53-14-20(41)25(44)24(43)19(40)12-35-16-5-4-6-17(11-16)37-22(42)8-3-2-7-18-9-10-58-59-18;;/h4-6,11,18-21,23-31,33-35,38,40-41,43-47H,2-3,7-10,12-14H2,1H3,(H,36,39)(H,37,42)(H,48,49)(H,50,51,52);;/q;2*+1/p-2/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28-,29+,30-,31+,33-,34+;;/s2
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n/an/an/a 62n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50179253
PNG
((2R,3S,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-2-{[(2R,3S,4...)
Show SMILES CCCCCCCCO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H]2O)[C@@H]1O
Show InChI InChI=1S/C38H68O26/c1-2-3-4-5-6-7-8-55-38-33(25(50)20(45)15(10-40)60-38)64-37-29(54)32(23(48)18(13-43)59-37)63-36-28(53)31(22(47)17(12-42)58-36)62-35-27(52)30(21(46)16(11-41)57-35)61-34-26(51)24(49)19(44)14(9-39)56-34/h14-54H,2-13H2,1H3/t14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35-,36-,37-,38+/m1/s1
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n/an/an/a 68n/an/an/an/an/a



Progen Industries Limited

Curated by ChEMBL


Assay Description
Binding affinity for FGF2 by BIAcore solution affinity assay


J Med Chem 48: 8229-36 (2005)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307396
PNG
(12-(4-Naphthalen-1-yl[1,2,3]triazol-1-yl)dodecyl 2...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCCCCCCCCCCn2cc(nn2)-c2cccc3ccccc23)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C54H83N3O74S16/c58-132(59,60)107-21-30-35(121-137(73,74)75)40(117-52-47(129-145(97,98)99)41(36(122-138(76,77)78)31(114-52)22-108-133(61,62)63)119-54-49(131-147(103,104)105)44(127-143(91,92)93)39(125-141(85,86)87)34(116-54)25-111-136(70,71)72)46(128-144(94,95)96)51(113-30)118-42-37(123-139(79,80)81)32(23-109-134(64,65)66)115-53(48(42)130-146(100,101)102)120-45-43(126-142(88,89)90)38(124-140(82,83)84)33(24-110-135(67,68)69)112-50(45)106-19-12-8-6-4-2-1-3-5-7-11-18-57-20-29(55-56-57)28-17-13-15-26-14-9-10-16-27(26)28/h9-10,13-17,20,30-54H,1-8,11-12,18-19,21-25H2,(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)(H,88,89,90)(H,91,92,93)(H,94,95,96)(H,97,98,99)(H,100,101,102)(H,103,104,105)/p-16/t30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40+,41+,42+,43+,44+,45+,46+,47+,48+,49+,50+,51-,52-,53-,54-/m1/s1
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n/an/an/a 73n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307400
PNG
(CHEMBL604366 | hexadecasodium [3-({4-[(4-{[3,5-bis...)
Show SMILES CCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C38H68O74S16/c1-2-3-4-5-6-7-8-87-34-29(27(107-123(69,70)71)22(105-121(63,64)65)17(93-34)12-91-116(48,49)50)101-37-32(111-127(81,82)83)26(21(104-120(60,61)62)16(96-37)11-90-115(45,46)47)99-35-30(109-125(75,76)77)24(19(102-118(54,55)56)14(94-35)9-88-113(39,40)41)98-36-31(110-126(78,79)80)25(20(103-119(57,58)59)15(95-36)10-89-114(42,43)44)100-38-33(112-128(84,85)86)28(108-124(72,73)74)23(106-122(66,67)68)18(97-38)13-92-117(51,52)53/h14-38H,2-13H2,1H3,(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)/p-16/t14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35-,36-,37-,38-/m1/s1
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n/an/an/a 82n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307392
PNG
(3-(4-Phenyl[1,2,3]triazol-1-yl)propyl 2,3,4,6-Tetr...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCn2cc(nn2)-c2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C41H63N3O74S16/c45-119(46,47)94-10-17-22(108-124(60,61)62)27(104-39-34(116-132(84,85)86)28(23(109-125(63,64)65)18(101-39)11-95-120(48,49)50)106-41-36(118-134(90,91)92)31(114-130(78,79)80)26(112-128(72,73)74)21(103-41)14-98-123(57,58)59)33(115-131(81,82)83)38(100-17)105-29-24(110-126(66,67)68)19(12-96-121(51,52)53)102-40(35(29)117-133(87,88)89)107-32-30(113-129(75,76)77)25(111-127(69,70)71)20(13-97-122(54,55)56)99-37(32)93-8-4-7-44-9-16(42-43-44)15-5-2-1-3-6-15/h1-3,5-6,9,17-41H,4,7-8,10-14H2,(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)(H,87,88,89)(H,90,91,92)/p-16/t17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27+,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38-,39-,40-,41-/m1/s1
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n/an/an/a 83n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50179256
PNG
(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d...)
Show SMILES OC[C@H]1O[C@H](NC(=O)CCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H]4O)[C@@H]3O)[C@@H]2O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C46H78N4O28S/c51-10-17-27(59)32(64)40(41(70-17)49-24(57)8-2-1-5-9-47-23(56)7-4-3-6-22-25-16(15-79-22)48-46(69)50-25)78-45-36(68)39(30(62)21(14-55)74-45)77-44-35(67)38(29(61)20(13-54)73-44)76-43-34(66)37(28(60)19(12-53)72-43)75-42-33(65)31(63)26(58)18(11-52)71-42/h16-22,25-45,51-55,58-68H,1-15H2,(H,47,56)(H,49,57)(H2,48,50,69)/t16-,17+,18+,19+,20+,21+,22-,25-,26+,27+,28+,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42+,43+,44+,45+/m0/s1
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n/an/an/a 84n/an/an/an/an/a



Progen Industries Limited

Curated by ChEMBL


Assay Description
Binding affinity for FGF2 by BIAcore solution affinity assay


J Med Chem 48: 8229-36 (2005)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84571
PNG
(Linked sulfated tetracyclitol, 12)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=CC([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)CN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C32H51N3O60S15/c36-96(37,38)81-18-6-1-13(23(86-101(51,52)53)28(18)91-106(66,67)68)33(11-34(14-2-7-19(82-97(39,40)41)29(92-107(69,70)71)24(14)87-102(54,55)56)15-3-8-20(83-98(42,43)44)30(93-108(72,73)74)25(15)88-103(57,58)59)12-35(16-4-9-21(84-99(45,46)47)31(94-109(75,76)77)26(16)89-104(60,61)62)17-5-10-22(85-100(48,49)50)32(95-110(78,79)80)27(17)90-105(63,64)65/h1-10,13-32,102H,11-12H2,(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H2,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)/p-15/t13?,14-,15-,16-,17-,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+/m0/s1
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n/an/an/a 85n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50179254
PNG
((2R,3S,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-2-{[(2R,3S,4...)
Show SMILES OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@H](O[C@H]3[C@H](O)[C@@H](CO)O[C@H](O[C@H]4[C@H](O)[C@@H](CO)O[C@H](O[C@H]5[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]5OCc5ccccc5)[C@H]4O)[C@H]3O)[C@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C37H58O26/c38-6-13-18(43)23(48)25(50)33(55-13)60-29-20(45)15(8-40)56-34(26(29)51)61-30-21(46)16(9-41)57-35(27(30)52)62-31-22(47)17(10-42)58-36(28(31)53)63-32-24(49)19(44)14(7-39)59-37(32)54-11-12-4-2-1-3-5-12/h1-5,13-53H,6-11H2/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33-,34-,35-,36-,37+/m1/s1
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n/an/an/a 86n/an/an/an/an/a



Progen Industries Limited

Curated by ChEMBL


Assay Description
Binding affinity for FGF2 by BIAcore solution affinity assay


J Med Chem 48: 8229-36 (2005)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307394
PNG
(3-(5-Dimethylaminonaphthalene-1-sulfonamido)propyl...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C45H70N2O76S17/c1-47(2)19-8-3-7-18-17(19)6-4-9-25(18)124(48,49)46-10-5-11-98-41-36(34(118-135(80,81)82)29(116-133(74,75)76)23(104-41)15-102-128(59,60)61)112-44-39(122-139(92,93)94)33(28(115-132(71,72)73)22(107-44)14-101-127(56,57)58)110-42-37(120-137(86,87)88)31(26(113-130(65,66)67)20(105-42)12-99-125(50,51)52)109-43-38(121-138(89,90)91)32(27(114-131(68,69)70)21(106-43)13-100-126(53,54)55)111-45-40(123-140(95,96)97)35(119-136(83,84)85)30(117-134(77,78)79)24(108-45)16-103-129(62,63)64/h3-4,6-9,20-24,26-46H,5,10-16H2,1-2H3,(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)(H,86,87,88)(H,89,90,91)(H,92,93,94)(H,95,96,97)/p-16/t20-,21-,22-,23-,24-,26-,27-,28-,29-,30-,31+,32+,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44-,45-/m1/s1
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n/an/an/a 86n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84566
PNG
(Linked sulfated tetracyclitol, 7)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C31H50N2O48S12/c34-82(35,36)70-20-10-6-16(24(74-86(46,47)48)28(20)78-90(58,59)60)32(17-7-11-21(71-83(37,38)39)29(79-91(61,62)63)25(17)75-87(49,50)51)14-4-2-1-3-5-15-33(18-8-12-22(72-84(40,41)42)30(80-92(64,65)66)26(18)76-88(52,53)54)19-9-13-23(73-85(43,44)45)31(81-93(67,68)69)27(19)77-89(55,56)57/h6-13,16-31H,1-5,14-15H2,(H,34,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)/p-12/t16-,17-,18-,19-,20+,21+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+/m0/s1
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n/an/an/a 90n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307398
PNG
(CHEMBL603122 | Hexadecasodium [2-(benzyloxy)-3-({4...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCc2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C37H58O74S16/c38-112(39,40)87-7-13-18(101-117(53,54)55)23(97-35-30(109-125(77,78)79)24(19(102-118(56,57)58)14(94-35)8-88-113(41,42)43)99-37-32(111-127(83,84)85)27(107-123(71,72)73)22(105-121(65,66)67)17(96-37)11-91-116(50,51)52)29(108-124(74,75)76)34(93-13)98-25-20(103-119(59,60)61)15(9-89-114(44,45)46)95-36(31(25)110-126(80,81)82)100-28-26(106-122(68,69)70)21(104-120(62,63)64)16(10-90-115(47,48)49)92-33(28)86-6-12-4-2-1-3-5-12/h1-5,13-37H,6-11H2,(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)/p-16/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35-,36-,37-/m1/s1
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n/an/an/a 95n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063835
PNG
(CHEMBL3397493)
Show SMILES [Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O23S4.3Na/c1-15(39)36-23-28(57-34-31(60-64(52,53)54)29(59-63(49,50)51)27(46)30(58-34)32(47)48)26(45)21(13-38)56-33(23)55-14-20(41)25(44)24(43)19(40)12-35-16-5-4-6-17(11-16)37-22(42)8-3-2-7-18-9-10-61-62-18;;;/h4-6,11,18-21,23-31,33-35,38,40-41,43-46H,2-3,7-10,12-14H2,1H3,(H,36,39)(H,37,42)(H,47,48)(H,49,50,51)(H,52,53,54);;;/q;3*+1/p-3/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29-,30-,31+,33-,34+;;;/s2
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n/an/an/a 95n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063808
PNG
(CHEMBL3397497)
Show SMILES [Na+].[Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)C([O-])=O
Show InChI InChI=1/C34H53N3O26S5.4Na/c1-15(38)36-23-28(60-34-31(63-68(54,55)56)29(62-67(51,52)53)27(45)30(61-34)32(46)47)26(44)21(14-58-66(48,49)50)59-33(23)57-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-64-65-18;;;;/h4-6,11,18-21,23-31,33-35,39-40,42-45H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56);;;;/q;4*+1/p-4/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29-,30-,31+,33-,34+;;;;/s2
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n/an/an/a 99n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50388342
PNG
(CHEMBL2059242)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)NCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C45H83NO61S13/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-29(47)46-19-17-20-87-42-38(36(103-116(72,73)74)32(101-114(66,67)68)27(92-42)23-90-110(54,55)56)98-44-40(106-119(81,82)83)35(31(100-113(63,64)65)26(94-44)22-89-109(51,52)53)96-43-39(105-118(78,79)80)34(30(99-112(60,61)62)25(93-43)21-88-108(48,49)50)97-45-41(107-120(84,85)86)37(104-117(75,76)77)33(102-115(69,70)71)28(95-45)24-91-111(57,58)59/h25-28,30-45H,2-24H2,1H3,(H,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)/p-13/t25-,26-,27-,28-,30-,31-,32-,33-,34+,35+,36+,37+,38+,39+,40+,41+,42+,43-,44-,45-/m1/s1
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n/an/an/a 108n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF-2 by surface plasmon resonance assay


J Med Chem 55: 3804-13 (2012)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84567
PNG
(Linked sulfated tetracyclitol, 8)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCCCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C32H52N2O48S12/c35-83(36,37)71-21-11-7-17(25(75-87(47,48)49)29(21)79-91(59,60)61)33(18-8-12-22(72-84(38,39)40)30(80-92(62,63)64)26(18)76-88(50,51)52)15-5-3-1-2-4-6-16-34(19-9-13-23(73-85(41,42)43)31(81-93(65,66)67)27(19)77-89(53,54)55)20-10-14-24(74-86(44,45)46)32(82-94(68,69)70)28(20)78-90(56,57)58/h7-14,17-32H,1-6,15-16H2,(H,35,36,37)(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)/p-12/t17-,18-,19-,20-,21+,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+/m0/s1
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n/an/an/a 108n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307390
PNG
(8-(4-Naphthalen-1-yl[1,2,3]triazol-1-yl)octyl 2,3,...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCCCCCCn2cc(nn2)-c2cccc3ccccc23)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C44H65N3O60S13/c48-108(49,50)88-17-25-29(99-112(60,61)62)33(97-44-40(107-120(84,85)86)36(104-117(75,76)77)32(102-115(69,70)71)28(95-44)20-91-111(57,58)59)38(105-118(78,79)80)42(93-25)96-34-30(100-113(63,64)65)26(18-89-109(51,52)53)94-43(39(34)106-119(81,82)83)98-37-35(103-116(72,73)74)31(101-114(66,67)68)27(19-90-110(54,55)56)92-41(37)87-15-8-4-2-1-3-7-14-47-16-24(45-46-47)23-13-9-11-21-10-5-6-12-22(21)23/h5-6,9-13,16,25-44H,1-4,7-8,14-15,17-20H2,(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)/p-13/t25-,26-,27-,28-,29-,30-,31-,32-,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44-/m1/s1
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n/an/an/a 110n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50179255
PNG
(CHEMBL265885 | N-[(2S,3S,4S,5S,6R)-3-{[(2R,3S,4S,5...)
Show SMILES OC[C@H]1O[C@H](NC(=O)COc2ccccc2)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H]4O)[C@@H]3O)[C@@H]2O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C38H59NO27/c40-6-13-20(47)25(52)33(34(58-13)39-18(45)11-57-12-4-2-1-3-5-12)66-38-29(56)32(23(50)17(10-44)62-38)65-37-28(55)31(22(49)16(9-43)61-37)64-36-27(54)30(21(48)15(8-42)60-36)63-35-26(53)24(51)19(46)14(7-41)59-35/h1-5,13-17,19-38,40-44,46-56H,6-11H2,(H,39,45)/t13-,14-,15-,16-,17-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35-,36-,37-,38-/m1/s1
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n/an/an/a 112n/an/an/an/an/a



Progen Industries Limited

Curated by ChEMBL


Assay Description
Binding affinity for FGF2 by BIAcore solution affinity assay


J Med Chem 48: 8229-36 (2005)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307399
PNG
(Benzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosy...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCc2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C31H48O60S13/c32-92(33,34)72-7-12-16(83-96(44,45)46)20(81-31-27(91-104(68,69)70)23(88-101(59,60)61)19(86-99(53,54)55)15(79-31)10-75-95(41,42)43)25(89-102(62,63)64)29(77-12)80-21-17(84-97(47,48)49)13(8-73-93(35,36)37)78-30(26(21)90-103(65,66)67)82-24-22(87-100(56,57)58)18(85-98(50,51)52)14(9-74-94(38,39)40)76-28(24)71-6-11-4-2-1-3-5-11/h1-5,12-31H,6-10H2,(H,32,33,34)(H,35,36,37)(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)/p-13/t12-,13-,14-,15-,16-,17-,18-,19-,20+,21+,22+,23+,24+,25+,26+,27+,28+,29-,30-,31-/m1/s1
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n/an/an/a 129n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307391
PNG
(8-(5-Dimethylaminonaphthalene-1-sulfonamido)octyl ...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C44H70N2O62S14/c1-46(2)23-13-9-12-22-21(23)11-10-14-28(22)109(47,48)45-15-7-5-3-4-6-8-16-88-41-37(35(104-118(73,74)75)31(102-116(67,68)69)26(93-41)19-91-112(55,56)57)99-43-39(107-121(82,83)84)34(30(101-115(64,65)66)25(95-43)18-90-111(52,53)54)97-42-38(106-120(79,80)81)33(29(100-114(61,62)63)24(94-42)17-89-110(49,50)51)98-44-40(108-122(85,86)87)36(105-119(76,77)78)32(103-117(70,71)72)27(96-44)20-92-113(58,59)60/h9-14,24-27,29-45H,3-8,15-20H2,1-2H3,(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)/p-13/t24-,25-,26-,27-,29-,30-,31-,32-,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44-/m1/s1
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n/an/an/a 130n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84565
PNG
(Linked sulfated tetracyclitol, 6)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C30H48N2O48S12/c33-81(34,35)69-19-9-5-15(23(73-85(45,46)47)27(19)77-89(57,58)59)31(16-6-10-20(70-82(36,37)38)28(78-90(60,61)62)24(16)74-86(48,49)50)13-3-1-2-4-14-32(17-7-11-21(71-83(39,40)41)29(79-91(63,64)65)25(17)75-87(51,52)53)18-8-12-22(72-84(42,43)44)30(80-92(66,67)68)26(18)76-88(54,55)56/h5-12,15-30H,1-4,13-14H2,(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)/p-12/t15-,16-,17-,18-,19+,20+,21+,22+,23+,24+,25+,26+,27+,28+,29+,30+/m0/s1
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n/an/an/a 135n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307388
PNG
(8-(4-Phenyl[1,2,3]triazol-1-yl)octyl 2,3,4,6-Tetra...)
Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](OCCCCCCCCn3cc(nn3)-c3ccccc3)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C40H63N3O60S13/c44-104(45,46)84-15-21-25(95-108(56,57)58)29(93-40-36(103-116(80,81)82)32(100-113(71,72)73)28(98-111(65,66)67)24(91-40)18-87-107(53,54)55)34(101-114(74,75)76)38(89-21)92-30-26(96-109(59,60)61)22(16-85-105(47,48)49)90-39(35(30)102-115(77,78)79)94-33-31(99-112(68,69)70)27(97-110(62,63)64)23(17-86-106(50,51)52)88-37(33)83-13-9-4-2-1-3-8-12-43-14-20(41-42-43)19-10-6-5-7-11-19/h5-7,10-11,14,21-40H,1-4,8-9,12-13,15-18H2,(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)/p-13/t21-,22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36+,37+,38-,39-,40-/m1/s1
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n/an/an/a 140n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50063837
PNG
(CHEMBL3397492)
Show SMILES [Na+].[Na+].[Na+].CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](COS([O-])(=O)=O)[C@H](O)[C@@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](OS([O-])(=O)=O)[C@H]1O)C([O-])=O
Show InChI InChI=1/C34H53N3O23S4.3Na/c1-15(38)36-23-29(58-34-28(46)30(60-64(52,53)54)27(45)31(59-34)32(47)48)26(44)21(14-56-63(49,50)51)57-33(23)55-13-20(40)25(43)24(42)19(39)12-35-16-5-4-6-17(11-16)37-22(41)8-3-2-7-18-9-10-61-62-18;;;/h4-6,11,18-21,23-31,33-35,39-40,42-46H,2-3,7-10,12-14H2,1H3,(H,36,38)(H,37,41)(H,47,48)(H,49,50,51)(H,52,53,54);;;/q;3*+1/p-3/t18?,19-,20+,21+,23+,24+,25+,26-,27-,28+,29+,30-,31-,33-,34+;;;/s2
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n/an/an/a 147n/an/an/an/an/a



Kagoshima University

Curated by ChEMBL


Assay Description
Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance method


Bioorg Med Chem Lett 25: 1407-11 (2015)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84564
PNG
(Linked sulfated tetracyclitol, 5)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C29H46N2O48S12/c32-80(33,34)68-18-8-4-14(22(72-84(44,45)46)26(18)76-88(56,57)58)30(15-5-9-19(69-81(35,36)37)27(77-89(59,60)61)23(15)73-85(47,48)49)12-2-1-3-13-31(16-6-10-20(70-82(38,39)40)28(78-90(62,63)64)24(16)74-86(50,51)52)17-7-11-21(71-83(41,42)43)29(79-91(65,66)67)25(17)75-87(53,54)55/h4-11,14-29H,1-3,12-13H2,(H,32,33,34)(H,35,36,37)(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)/p-12/t14-,15-,16-,17-,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+,28+,29+/m0/s1
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n/an/an/a 148n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307401
PNG
(CHEMBL602113 | Octyl 2,3,4,6-Tetra-O-sulfo-alpha-D...)
Show SMILES CCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C32H58O60S13/c1-2-3-4-5-6-7-8-72-29-25(23(88-101(57,58)59)19(86-99(51,52)53)15(77-29)11-75-95(39,40)41)83-31-27(91-104(66,67)68)22(18(85-98(48,49)50)14(79-31)10-74-94(36,37)38)81-30-26(90-103(63,64)65)21(17(84-97(45,46)47)13(78-30)9-73-93(33,34)35)82-32-28(92-105(69,70)71)24(89-102(60,61)62)20(87-100(54,55)56)16(80-32)12-76-96(42,43)44/h13-32H,2-12H2,1H3,(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)/p-13/t13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23+,24+,25+,26+,27+,28+,29+,30-,31-,32-/m1/s1
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Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50307402
PNG
(4-Butylbenzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannop...)
Show SMILES CCCCc1ccc(CO[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]2O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)cc1
Show InChI InChI=1S/C35H56O60S13/c1-2-3-4-14-5-7-15(8-6-14)9-75-32-28(26(91-104(60,61)62)22(89-102(54,55)56)18(80-32)12-78-98(42,43)44)86-34-30(94-107(69,70)71)25(21(88-101(51,52)53)17(82-34)11-77-97(39,40)41)84-33-29(93-106(66,67)68)24(20(87-100(48,49)50)16(81-33)10-76-96(36,37)38)85-35-31(95-108(72,73)74)27(92-105(63,64)65)23(90-103(57,58)59)19(83-35)13-79-99(45,46)47/h5-8,16-35H,2-4,9-13H2,1H3,(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)/p-13/t16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33-,34-,35-/m1/s1
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n/an/an/a 160n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF2 by surface plasmon-based solution affinity assay


J Med Chem 53: 1686-99 (2010)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50388341
PNG
(CHEMBL2059241)
Show SMILES CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C51H88O60S13/c1-22(2)7-6-8-23(3)27-11-12-28-26-10-9-24-17-25(13-15-50(24,4)29(26)14-16-51(27,28)5)95-46-42(40(107-120(76,77)78)36(105-118(70,71)72)32(96-46)20-93-114(58,59)60)102-48-44(110-123(85,86)87)39(35(104-117(67,68)69)31(98-48)19-92-113(55,56)57)100-47-43(109-122(82,83)84)38(34(103-116(64,65)66)30(97-47)18-91-112(52,53)54)101-49-45(111-124(88,89)90)41(108-121(79,80)81)37(106-119(73,74)75)33(99-49)21-94-115(61,62)63/h22-49H,6-21H2,1-5H3,(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)(H,88,89,90)/p-13/t23-,24+,25+,26+,27-,28+,29+,30-,31-,32-,33-,34-,35-,36-,37-,38+,39+,40+,41+,42+,43+,44+,45+,46+,47-,48-,49-,50+,51-/m1/s1
PDB
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n/an/an/a 160n/an/an/an/an/a



Progen Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Binding affinity to FGF-2 by surface plasmon resonance assay


J Med Chem 55: 3804-13 (2012)

More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84563
PNG
(Linked sulfated tetracyclitol, 4)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C28H44N2O48S12/c31-79(32,33)67-17-7-3-13(21(71-83(43,44)45)25(17)75-87(55,56)57)29(14-4-8-18(68-80(34,35)36)26(76-88(58,59)60)22(14)72-84(46,47)48)11-1-2-12-30(15-5-9-19(69-81(37,38)39)27(77-89(61,62)63)23(15)73-85(49,50)51)16-6-10-20(70-82(40,41)42)28(78-90(64,65)66)24(16)74-86(52,53)54/h3-10,13-28H,1-2,11-12H2,(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)/p-12/t13-,14-,15-,16-,17+,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+,28+/m0/s1
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n/an/an/a 161n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84568
PNG
(Linked sulfated tetracyclitol, 9)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCCCCCCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C33H54N2O48S12/c36-84(37,38)72-22-12-8-18(26(76-88(48,49)50)30(22)80-92(60,61)62)34(19-9-13-23(73-85(39,40)41)31(81-93(63,64)65)27(19)77-89(51,52)53)16-6-4-2-1-3-5-7-17-35(20-10-14-24(74-86(42,43)44)32(82-94(66,67)68)28(20)78-90(54,55)56)21-11-15-25(75-87(45,46)47)33(83-95(69,70)71)29(21)79-91(57,58)59/h8-15,18-33H,1-7,16-17H2,(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)/p-12/t18-,19-,20-,21-,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+/m0/s1
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n/an/an/a 194n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM84562
PNG
(Linked sulfated tetracyclitol, 3)
Show SMILES [O-]S(=O)(=O)O[C@@H]1C=C[C@@H]([C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)N(CCCN([C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)[C@H]1C=C[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O
Show InChI InChI=1S/C27H42N2O48S12/c30-78(31,32)66-16-6-2-12(20(70-82(42,43)44)24(16)74-86(54,55)56)28(13-3-7-17(67-79(33,34)35)25(75-87(57,58)59)21(13)71-83(45,46)47)10-1-11-29(14-4-8-18(68-80(36,37)38)26(76-88(60,61)62)22(14)72-84(48,49)50)15-5-9-19(69-81(39,40)41)27(77-89(63,64)65)23(15)73-85(51,52)53/h2-9,12-27H,1,10-11H2,(H,30,31,32)(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)/p-12/t12-,13-,14-,15-,16+,17+,18+,19+,20+,21+,22+,23+,24+,25+,26+,27+/m0/s1
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n/an/an/a 248n/an/an/a7.4n/a



Progen Industries Ltd.



Assay Description
Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...


Chembiochem 6: 1882-90 (2005)

Checked by Author
More data for this
Ligand-Target Pair
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