Found 10 hits of ki for UniProtKB: P16233 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50212744
(CHEBI:35020 | TRIBUTYRIN)Show InChI InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| | <1 | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a |
TBA
| Assay Description
Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM sodium taurodeoxycholatet (NaTDC) at a compou... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2B56MWT |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50212746
(CHEMBL119630)Show SMILES [H][C@]12C[C@@H](OC(=O)CCC)[C@@]1([H])CC=C2 |c:14| Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 220 | n/a | n/a | n/a | n/a | 220 | n/a | n/a | n/a |
TBA
| Assay Description
Tested for hydrolysis with 0.5 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2B56MWT |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50212746
(CHEMBL119630)Show SMILES [H][C@]12C[C@@H](OC(=O)CCC)[C@@]1([H])CC=C2 |c:14| Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 710 | n/a | n/a | n/a | n/a | 710 | n/a | n/a | n/a |
TBA
| Assay Description
Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase), 2.2 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2B56MWT |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50212744
(CHEBI:35020 | TRIBUTYRIN)Show InChI InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| | 1.10E+3 | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a |
TBA
| Assay Description
Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at a compound dose of 0.2 g |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2B56MWT |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50212746
(CHEMBL119630)Show SMILES [H][C@]12C[C@@H](OC(=O)CCC)[C@@]1([H])CC=C2 |c:14| Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 2.10E+3 | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a |
TBA
| Assay Description
Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at the compound dose of 0.2 g |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2B56MWT |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50212746
(CHEMBL119630)Show SMILES [H][C@]12C[C@@H](OC(=O)CCC)[C@@]1([H])CC=C2 |c:14| Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | 5.70E+3 | n/a | n/a | n/a | n/a | 5.70E+3 | n/a | n/a | n/a |
TBA
| Assay Description
Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase)at the compound dose of 0.2 g |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2B56MWT |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50381861
(CHEMBL2022676)Show SMILES CCCCCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1 |r| Show InChI InChI=1S/C35H44N4O5/c1-2-3-4-5-12-23-44-29-19-17-28(18-20-29)37-32(40)21-22-33(41)38-31(25-27-15-10-7-11-16-27)35(43)39-30(34(36)42)24-26-13-8-6-9-14-26/h6-11,13-20,30-31H,2-5,12,21-25H2,1H3,(H2,36,42)(H,37,40)(H,38,41)(H,39,43)/t30-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis |
Bioorg Med Chem Lett 22: 3147-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50381860
(CHEMBL2022680)Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1 |r| Show InChI InChI=1S/C32H38N4O6/c1-2-3-19-42-26-15-11-24(12-16-26)34-29(38)17-18-30(39)35-28(21-23-9-13-25(37)14-10-23)32(41)36-27(31(33)40)20-22-7-5-4-6-8-22/h4-16,27-28,37H,2-3,17-21H2,1H3,(H2,33,40)(H,34,38)(H,35,39)(H,36,41)/t27-,28-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis |
Bioorg Med Chem Lett 22: 3147-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50381859
(CHEMBL2022681)Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@H](C(=O)N[C@H](C(N)=O)c2ccc3ccccc3c2)c2ccc3ccccc3c2)cc1 |r| Show InChI InChI=1S/C38H38N4O5/c1-2-3-22-47-32-18-16-31(17-19-32)40-33(43)20-21-34(44)41-36(30-15-13-26-9-5-7-11-28(26)24-30)38(46)42-35(37(39)45)29-14-12-25-8-4-6-10-27(25)23-29/h4-19,23-24,35-36H,2-3,20-22H2,1H3,(H2,39,45)(H,40,43)(H,41,44)(H,42,46)/t35-,36-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis |
Bioorg Med Chem Lett 22: 3147-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF |
More data for this
Ligand-Target Pair | |
Pancreatic triacylglycerol lipase
(Homo sapiens (Human)) | BDBM50381858
(CHEMBL2022679)Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)cc1 |r| Show InChI InChI=1S/C32H38N4O6/c1-2-3-19-42-26-15-11-24(12-16-26)34-29(38)17-18-30(39)35-28(21-22-7-5-4-6-8-22)32(41)36-27(31(33)40)20-23-9-13-25(37)14-10-23/h4-16,27-28,37H,2-3,17-21H2,1H3,(H2,33,40)(H,34,38)(H,35,39)(H,36,41)/t27-,28-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis |
Bioorg Med Chem Lett 22: 3147-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF |
More data for this
Ligand-Target Pair | |
Search and Browse
