Found 23 hits of ic50 data for polymerid = 50000150 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177407
(1-(4-hydroxyphenyl)prop-2-en-1-one | 4-acryloylphe...)Show InChI InChI=1S/C9H8O2/c1-2-9(11)7-3-5-8(10)6-4-7/h2-6,10H,1H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177412
(4-(aminomethyl)phenol | 4-hydroxybenzylamine | CHE...)Show InChI InChI=1S/C7H9NO/c8-5-6-1-3-7(9)4-2-6/h1-4,9H,5,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177410
(4-hydroxy-3-nitrobenzaldehyde | CHEMBL378361)Show InChI InChI=1S/C7H5NO4/c9-4-5-1-2-7(10)6(3-5)8(11)12/h1-4,10H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177411
(4-formylphenol | 4-hydroxybenzaldehyde | CHEMBL141...)Show InChI InChI=1S/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177405
(3-methoxy-4-hydroxybenzaldehyde | 4-hydroxy-3-meth...)Show InChI InChI=1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177402
(1-(4-hydroxy-phenyl)-propan-1-one | 1-(4-hydroxyph...)Show InChI InChI=1S/C9H10O2/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177409
((4-hydroxyphenyl)ethan-1-one | 1-(4-hydroxyphenyl)...)Show InChI InChI=1S/C8H8O2/c1-6(9)7-2-4-8(10)5-3-7/h2-5,10H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.88E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177413
(4-hydroxy-3-methoxybenzaldehyde oxime | CHEMBL2024...)Show InChI InChI=1S/C8H9NO3/c1-12-8-4-6(5-9-11)2-3-7(8)10/h2-4,10H,5H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177406
(4-hydroxybenzaldehyde oxime | CHEMBL202611)Show InChI InChI=1S/C7H7NO2/c9-7-3-1-6(2-4-7)5-8-10/h1-4,9H,5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM26194
(4-Hydroxybenzoate, III | 4-hydroxybenzoic acid | C...)Show InChI InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177403
((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-(hydroxyme...)Show SMILES OC[C@H]1O[C@@H](Oc2ccc(CO)cc2)[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177408
(4-(hydroxymethyl)phenol | 4-Hydroxybenzyl alcohol ...)Show InChI InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50139370
(4-Methoxy-benzaldehyde | 4-methoxybenzaldehyde | C...)Show InChI InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50177404
(4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymet...)Show SMILES OC[C@H]1O[C@@H](Oc2ccc(C=O)cc2)[C@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C13H16O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-5,9-13,15-18H,6H2/t9-,10-,11-,12-,13-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50145829
(4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL...)Show InChI InChI=1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibitory activity against GABAT |
Bioorg Med Chem Lett 16: 592-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.10.040 BindingDB Entry DOI: 10.7270/Q29G5MCH |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50226518
(3-Aminobenzoesaeure | 3-aminobenzoic acid | CHEMBL...)Show InChI InChI=1S/C7H7NO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50376750
(CHEMBL541141)Show InChI InChI=1S/C8H9NO2/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4H,5,9H2,(H,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50376751
(ANTHRANILIC ACID)Show InChI InChI=1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank KEGG MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50376752
(CHEMBL535644)Show InChI InChI=1S/C9H11NO2/c10-6-8-4-2-1-3-7(8)5-9(11)12/h1-4H,5-6,10H2,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50376753
(CHEMBL535415)Show InChI InChI=1S/C8H9NO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4H,5,9H2,(H,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50376754
(CHEMBL535865)Show InChI InChI=1S/C8H9NO2/c9-7-3-1-2-6(4-7)5-8(10)11/h1-4H,5,9H2,(H,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50376755
(CHEMBL535643)Show InChI InChI=1S/C9H11NO2/c10-6-8-3-1-2-7(4-8)5-9(11)12/h1-4H,5-6,10H2,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibition of GABA-AT |
Bioorg Med Chem Lett 18: 3122-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.060 BindingDB Entry DOI: 10.7270/Q22J6CRF |
More data for this Ligand-Target Pair | |
4-aminobutyrate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50009001
(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.28E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Punjabi University
Curated by ChEMBL
| Assay Description Inhibition of GABA transaminase (unknown origin) |
Eur J Med Chem 84: 206-39 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.013 BindingDB Entry DOI: 10.7270/Q2GH9KMN |
More data for this Ligand-Target Pair | |