Compile Data Set for Download or QSAR

Found 75 hits of ic50 for UniProtKB: P06858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lipoprotein lipase (Homo sapiens (Human))	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O |r| Show InChI InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human LPL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by sub...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50138739 (4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...) Show SMILES COc1nn(-c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)c(=O)o1 Show InChI InChI=1S/C20H21N3O4/c1-20(2,3)14-7-5-13(6-8-14)17(24)21-15-9-11-16(12-10-15)23-19(25)27-18(22-23)26-4/h5-12H,1-4H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit lipoprotein lipase (LPL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364285 (CHEMBL1952298) Show SMILES CCCCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C17H29BO2/c1-2-3-4-5-6-7-8-9-10-11-16-12-14-17(15-13-16)18(19)20/h12-15,19-20H,2-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50433472 (CHEMBL2381069) Show SMILES Fc1ccccc1CSC(=O)NCCCCCCc1ccccc1 Show InChI InChI=1S/C20H24FNOS/c21-19-14-8-7-13-18(19)16-24-20(23)22-15-9-2-1-4-10-17-11-5-3-6-12-17/h3,5-8,11-14H,1-2,4,9-10,15-16H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development, LLC Curated by ChEMBL					Assay Description Inhibition of human LPL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometry				Bioorg Med Chem Lett 23: 2595-7 (2013) Article DOI: 10.1016/j.bmcl.2013.02.113 BindingDB Entry DOI: 10.7270/Q24T6KQV
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444153 (CHEMBL3093304) Show SMILES OC(=O)c1cc(ccc1N1CCC(Cc2ccc(F)cc2)C1)C(F)(F)F Show InChI InChI=1S/C19H17F4NO2/c20-15-4-1-12(2-5-15)9-13-7-8-24(11-13)17-6-3-14(19(21,22)23)10-16(17)18(25)26/h1-6,10,13H,7-9,11H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364283 (CHEMBL1952296) Show SMILES CCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C11H17BO2/c1-2-3-4-5-10-6-8-11(9-7-10)12(13)14/h6-9,13-14H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364295 (CHEMBL1952307) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H21BO2/c1-17(2)18(3,4)21-19(20-17)16-12-10-15(11-13-16)14-8-6-5-7-9-14/h5-13H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364298 (CHEMBL1952310) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)13-9-7-12(8-10-13)14-6-5-11-20-14/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364282 (CHEMBL1952295) Show SMILES CCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C9H13BO2/c1-2-3-8-4-6-9(7-5-8)10(11)12/h4-7,11-12H,2-3H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50067895 (CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...) Show SMILES Cc1ccc(cc1)B(O)O Show InChI InChI=1S/C7H9BO2/c1-6-2-4-7(5-3-6)8(9)10/h2-5,9-10H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364281 (CHEMBL1952294) Show SMILES CCc1ccc(cc1)B(O)O Show InChI InChI=1S/C8H11BO2/c1-2-7-3-5-8(6-4-7)9(10)11/h3-6,10-11H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364284 (CHEMBL1952297) Show SMILES CCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C13H21BO2/c1-2-3-4-5-6-7-12-8-10-13(11-9-12)14(15)16/h8-11,15-16H,2-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364297 (CHEMBL1952309) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C16H19BO3/c1-15(2)16(3,4)20-17(19-15)13-9-7-12(8-10-13)14-6-5-11-18-14/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444145 (CHEMBL3093405) Show SMILES OC(=O)c1cc(ccc1NCC1CC1)C(F)(F)F Show InChI InChI=1S/C12H12F3NO2/c13-12(14,15)8-3-4-10(9(5-8)11(17)18)16-6-7-1-2-7/h3-5,7,16H,1-2,6H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50138734 (3-(3-(benzyloxy)phenyl)-5-ethoxy-1,3,4-oxadiazol-2...) Show SMILES CCOc1nn(-c2cccc(OCc3ccccc3)c2)c(=O)o1 Show InChI InChI=1S/C17H16N2O4/c1-2-21-16-18-19(17(20)23-16)14-9-6-10-15(11-14)22-12-13-7-4-3-5-8-13/h3-11H,2,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit lipoprotein lipase (LPL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364295 (CHEMBL1952307) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H21BO2/c1-17(2)18(3,4)21-19(20-17)16-12-10-15(11-13-16)14-8-6-5-7-9-14/h5-13H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50521226 (CHEMBL4471545) Show SMILES CS(=O)(=O)C(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(cc2s1)-c1ccccc1 Show InChI InChI=1S/C18H17N5O5S3/c1-30(24,25)16(17-23-22-15(28-17)10-20-31(19,26)27)18-21-13-8-7-12(9-14(13)29-18)11-5-3-2-4-6-11/h2-9,16,20H,10H2,1H3,(H2,19,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human LPL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by sub...				ACS Med Chem Lett 9: 1263-1268 (2018) Article DOI: 10.1021/acsmedchemlett.8b00424 BindingDB Entry DOI: 10.7270/Q2TF01QC
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364282 (CHEMBL1952295) Show SMILES CCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C9H13BO2/c1-2-3-8-4-6-9(7-5-8)10(11)12/h4-7,11-12H,2-3H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364300 (CHEMBL1952312) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)14-7-5-12(6-8-14)13-9-10-20-11-13/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364283 (CHEMBL1952296) Show SMILES CCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C11H17BO2/c1-2-3-4-5-10-6-8-11(9-7-10)12(13)14/h6-9,13-14H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364293 (CHEMBL1952305) Show SMILES CCCCCCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C23H39BO2/c1-6-7-8-9-10-11-12-13-14-15-20-16-18-21(19-17-20)24-25-22(2,3)23(4,5)26-24/h16-19H,6-15H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364301 (CHEMBL1952313) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23BO2/c1-21(2)22(3,4)25-23(24-21)20-13-11-17(12-14-20)19-10-9-16-7-5-6-8-18(16)15-19/h5-15H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364299 (CHEMBL1952311) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccoc1 Show InChI InChI=1S/C16H19BO3/c1-15(2)16(3,4)20-17(19-15)14-7-5-12(6-8-14)13-9-10-18-11-13/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364292 (CHEMBL1949700) Show SMILES CCCCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C21H35BO2/c1-6-7-8-9-10-11-12-13-18-14-16-19(17-15-18)22-23-20(2,3)21(4,5)24-22/h14-17H,6-13H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364291 (CHEMBL1952304) Show SMILES CCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C19H31BO2/c1-6-7-8-9-10-11-16-12-14-17(15-13-16)20-21-18(2,3)19(4,5)22-20/h12-15H,6-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444152 (CHEMBL3093305) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(cn1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C18H14F6N2O3/c19-17(20,21)10-1-3-14(13(7-10)16(27)28)26-6-5-12(9-26)29-15-4-2-11(8-25-15)18(22,23)24/h1-4,7-8,12H,5-6,9H2,(H,27,28)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364281 (CHEMBL1952294) Show SMILES CCc1ccc(cc1)B(O)O Show InChI InChI=1S/C8H11BO2/c1-2-7-3-5-8(6-4-7)9(10)11/h3-6,10-11H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444138 (CHEMBL3093392) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r| Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364290 (CHEMBL1952303) Show SMILES CCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C17H27BO2/c1-6-7-8-9-14-10-12-15(13-11-14)18-19-16(2,3)17(4,5)20-18/h10-13H,6-9H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364301 (CHEMBL1952313) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23BO2/c1-21(2)22(3,4)25-23(24-21)20-13-11-17(12-14-20)19-10-9-16-7-5-6-8-18(16)15-19/h5-15H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364289 (CHEMBL1952302) Show SMILES CCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C15H23BO2/c1-6-7-12-8-10-13(11-9-12)16-17-14(2,3)15(4,5)18-16/h8-11H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50067895 (CHEMBL140780 | Tolyl boronic acid | p-tolylboronic...) Show SMILES Cc1ccc(cc1)B(O)O Show InChI InChI=1S/C7H9BO2/c1-6-2-4-7(5-3-6)8(9)10/h2-5,9-10H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364289 (CHEMBL1952302) Show SMILES CCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C15H23BO2/c1-6-7-12-8-10-13(11-9-12)16-17-14(2,3)15(4,5)18-16/h8-11H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364284 (CHEMBL1952297) Show SMILES CCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C13H21BO2/c1-2-3-4-5-6-7-12-8-10-13(11-9-12)14(15)16/h8-11,15-16H,2-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444151 (CHEMBL3093306) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(Cl)nc1)C(F)(F)F |r| Show InChI InChI=1S/C17H14ClF3N2O3/c18-15-4-2-11(8-22-15)26-12-5-6-23(9-12)14-3-1-10(17(19,20)21)7-13(14)16(24)25/h1-4,7-8,12H,5-6,9H2,(H,24,25)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364296 (CHEMBL1952308) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H20BFO2/c1-17(2)18(3,4)22-19(21-17)15-9-5-13(6-10-15)14-7-11-16(20)12-8-14/h5-12H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444147 (CHEMBL3093396) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCOCc1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C21H22F3NO4/c22-21(23,24)16-6-7-19(18(12-16)20(26)27)25-9-8-17(13-25)29-11-10-28-14-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,26,27)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444150 (CHEMBL3093307) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C19H17F4NO3/c20-14-4-1-12(2-5-14)11-27-15-7-8-24(10-15)17-6-3-13(19(21,22)23)9-16(17)18(25)26/h1-6,9,15H,7-8,10-11H2,(H,25,26)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444154 (CHEMBL3093303) Show SMILES OC(=O)c1cc(ccc1N1CC[C@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444148 (CHEMBL3093309) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCC1CC1)C(F)(F)F |r| Show InChI InChI=1S/C17H20F3NO3/c18-17(19,20)12-3-4-15(14(9-12)16(22)23)21-7-5-13(10-21)24-8-6-11-1-2-11/h3-4,9,11,13H,1-2,5-8,10H2,(H,22,23)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364299 (CHEMBL1952311) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccoc1 Show InChI InChI=1S/C16H19BO3/c1-15(2)16(3,4)20-17(19-15)14-7-5-12(6-8-14)13-9-10-18-11-13/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364297 (CHEMBL1952309) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C16H19BO3/c1-15(2)16(3,4)20-17(19-15)13-9-7-12(8-10-13)14-6-5-11-18-14/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364300 (CHEMBL1952312) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)14-7-5-12(6-8-14)13-9-10-20-11-13/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50458639 (CHEMBL4207216) Show SMILES CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:18| Show InChI InChI=1S/C15H16Cl2N2O3/c1-19-8-10(13(20)15(19)22)14(21)18-6-2-3-9-4-5-11(16)12(17)7-9/h4-5,7,20H,2-3,6,8H2,1H3,(H,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human LPL expressed in African green monkey COS7 cells using DGGR/DMPG vesicles as substrate pretreated for 10 mins followe...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364298 (CHEMBL1952310) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)13-9-7-12(8-10-13)14-6-5-11-20-14/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM26134 ((4-nonylphenyl)boranediol | Phenylboronic Acid, 13) Show SMILES CCCCCCCCCc1ccc(cc1)B(O)O Show InChI InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364294 (CHEMBL1952306) Show SMILES CCCCCc1cccc(c1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C17H27BO2/c1-6-7-8-10-14-11-9-12-15(13-14)18-19-16(2,3)17(4,5)20-18/h9,11-13H,6-8,10H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444139 (CHEMBL3093395) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1cncc(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N2O3/c19-13-5-11(7-23-8-13)10-27-14-3-4-24(9-14)16-2-1-12(18(20,21)22)6-15(16)17(25)26/h1-2,5-8,14H,3-4,9-10H2,(H,25,26)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444149 (CHEMBL3093308) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCC1CC1)C(F)(F)F |r| Show InChI InChI=1S/C16H18F3NO3/c17-16(18,19)11-3-4-14(13(7-11)15(21)22)20-6-5-12(8-20)23-9-10-1-2-10/h3-4,7,10,12H,1-2,5-6,8-9H2,(H,21,22)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 75 total )  |  Next  |  Last  >>

Jump to: