Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingomyelin phosphodiesterase 2 (Homo sapiens (Human)) | BDBM50122309 (((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy & Life Science Curated by ChEMBL | Assay Description Inhibitory activity of the compound against schyphostatin of neutral sphingomyelinase (N-SMase) from bovine brain microsome | Bioorg Med Chem Lett 13: 229-36 (2002) BindingDB Entry DOI: 10.7270/Q2K64HFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingomyelin phosphodiesterase 2 (Homo sapiens (Human)) | BDBM50122310 (((2R,3R,4R)-1,1-Difluoro-3-hexadecanoylamino-2,4-d...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.53E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy & Life Science Curated by ChEMBL | Assay Description Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomes | Bioorg Med Chem Lett 13: 229-36 (2002) BindingDB Entry DOI: 10.7270/Q2K64HFH | |||||||||||
More data for this Ligand-Target Pair |