Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus) | BDBM50529620 (CHEMBL4558600) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Laval Curated by ChEMBL | Assay Description Inhibition of glucose-6-phosphatase in rat H42E cells using glucose-6-phosphate as substrate preincubated overnight followed by substrate addition an... | J Nat Prod 81: 2169-2176 (2018) Article DOI: 10.1021/acs.jnatprod.8b00079 BindingDB Entry DOI: 10.7270/Q2VM4GRR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus) | BDBM50529620 (CHEMBL4558600) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Laval Curated by ChEMBL | Assay Description Inhibition of glucose-6-phosphatase in rat H42E cells using glucose-6-phosphate as substrate preincubated overnight followed by substrate addition an... | J Nat Prod 81: 2169-2176 (2018) Article DOI: 10.1021/acs.jnatprod.8b00079 BindingDB Entry DOI: 10.7270/Q2VM4GRR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus) | BDBM50389999 (CHEMBL2071306) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ottawa Curated by ChEMBL | Assay Description Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assay | J Nat Prod 75: 1284-8 (2012) Article DOI: 10.1021/np3001317 BindingDB Entry DOI: 10.7270/Q2VM4DBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus) | BDBM50294477 ((E)-1-(beta-D-glucopyranosyl)-4-(4'-chlorophenyl)b...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Inhibition of rat liver glucose-6-phosphatase | Bioorg Med Chem Lett 19: 2699-703 (2009) Article DOI: 10.1016/j.bmcl.2009.03.136 BindingDB Entry DOI: 10.7270/Q20V8CTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus) | BDBM50294478 ((E)-4-phenyl-1-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Inhibition of rat liver glucose-6-phosphatase | Bioorg Med Chem Lett 19: 2699-703 (2009) Article DOI: 10.1016/j.bmcl.2009.03.136 BindingDB Entry DOI: 10.7270/Q20V8CTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucose-6-phosphatase catalytic subunit 1 (Rattus norvegicus) | BDBM50390000 (CHEMBL2071309) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.91E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ottawa Curated by ChEMBL | Assay Description Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assay | J Nat Prod 75: 1284-8 (2012) Article DOI: 10.1021/np3001317 BindingDB Entry DOI: 10.7270/Q2VM4DBJ | |||||||||||
More data for this Ligand-Target Pair |