Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50105843 (2-Amino-N-{3-[4-(3-amino-propylamino)-butylamino]-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of recombinant GluA3 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 300 uM kainate-induced current by patch ... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50316373 (Argiotoxin-636 | CHEMBL1098240) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of recombinant GluA3 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch ... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50316373 (Argiotoxin-636 | CHEMBL1098240) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of GluA3 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiologica... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA3 | J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50184410 (CHEBI:71013 | E-2007 | E2007 | ER-155055-90 | Fyco...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50137124 (4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against Ionotropic glutamate receptor AMPA 3 of HEK293 cells in FLIPR assay | J Med Chem 46: 5834-43 (2003) Article DOI: 10.1021/jm030428j BindingDB Entry DOI: 10.7270/Q2KK9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (Homo sapiens (Human)) | BDBM50137125 (2-(3-(3-bromophenyl)ureido)-4-chlorobenzoic acid |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against Ionotropic glutamate receptor AMPA 3 of HEK293 cells in FLIPR assay | J Med Chem 46: 5834-43 (2003) Article DOI: 10.1021/jm030428j BindingDB Entry DOI: 10.7270/Q2KK9B60 | |||||||||||
More data for this Ligand-Target Pair |