Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50029417 (CHEMBL277363 | [4-(4-Methoxy-phenyl)-4H-benzo[b]py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50422202 (CHEMBL24662) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50018796 (2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50422200 (CHEMBL278804) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50422196 (CHEMBL25512) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50072809 (4-[2-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317840 (CHEMBL1099188 | diethyl 4-(2,3-difluorophenyl)-2,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317817 (3-cyclohex-2-enyl 5-methyl 2,6-dimethyl-4-(3-nitro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317813 (3-ethyl 5-(2-(methacryloyloxy)ethyl)2,6-dimethyl-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317802 (3-allyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317836 (3-methyl 5-(3-phenoxypropyl)2,6-dimethyl-4-(3-nitr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317833 (3-methyl 5-(3-phenylbutyl)2,6-dimethyl-4-(3-nitrop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317835 (3-(2-(benzyloxy)ethyl)5-methyl 2,6-dimethyl-4-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50422191 (CHEMBL24998) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317804 (3-allyl 5-ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317803 (3-allyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50280077 (CHEMBL18988 | sec-Butyl-[4-(2,4-dimethoxy-phenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317775 (CHEMBL1099222 | diethyl 2,6-dimethyl-4-(2-(methylt...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317826 (3-furan-2-ylmethyl 5-methyl 2,6-dimethyl-4-(3-nitr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317815 (3-benzyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317788 (CHEMBL1094989 | diethyl 2-butyl-6-methyl-4-(3-nitr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317821 (3-(3,4-difluorobenzyl)5-methyl 2,6-dimethyl-4-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317807 (3-cyclopropylmethyl 5-methyl 2,6-dimethyl-4-(3-nit...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317810 (3-methyl 5-(2,2,2-trifluoroethyl)2,6-dimethyl-4-(3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317809 (3-(2-chloroethyl)5-methyl 2,6-dimethyl-4-(3-nitrop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317825 (3-benzo[d][1,3]dioxol-5-ylmethyl 5-methyl 2,6-dime...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50422192 (CHEMBL25278) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317827 (3-methyl 5-thiophen-2-ylmethyl 2,6-dimethyl-4-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50072818 (4-[2-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317820 (3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50422203 (CHEMBL284195) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50029414 (Acetic acid 4-(4-methoxy-phenyl)-4H-benzo[b]pyrrol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317822 (3-methyl 5-(2,4,6-trichlorobenzyl)2,6-dimethyl-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317776 (CHEMBL1086836 | dimethyl 2,6-dimethyl-4-(2-(methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317805 (3-but-3-ynyl 5-methyl 2,6-dimethyl-4-(3-nitropheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317830 (3-cinnamyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317794 (CHEMBL1094740 | diethyl 2-(acetoxymethyl)-6-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317832 (3-methyl 5-(4-phenylbutyl)2,6-dimethyl-4-(3-nitrop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317834 (3-(4-(4-methoxyphenyl)butyl)5-methyl 2,6-dimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317831 (3-(4-chlorophenethyl)5-methyl 2,6-dimethyl-4-(3-ni...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50072811 (2,6-Dimethyl-4-[2-(4-methyl-5-oxy-furazan-3-ylmeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates. | J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317819 (3-(3,5-dinitrobenzyl)5-methyl 2,6-dimethyl-4-(3-ni...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317828 (3-(2,3-dihydro-1H-inden-2-yl)5-methyl 2,6-dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317798 (CHEMBL1098064 | diethyl 2-(2-cyanovinyl)-6-methyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317792 (CHEMBL1094405 | diethyl 2-(hydroxymethyl)-6-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50004704 ((+)-cis-Diltiazem | (2S,3S)-5-(2-(dimethylamino)et...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317829 (3-(2-(2-chlorophenoxy)ethyl)5-methyl 2,6-dimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50317806 (3-methyl 5-(3-methylbut-3-enyl)2,6-dimethyl-4-(3-n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay | Bioorg Med Chem 18: 3147-58 (2010) Article DOI: 10.1016/j.bmc.2010.03.038 BindingDB Entry DOI: 10.7270/Q2F47P90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) | BDBM50029426 (CHEMBL24675 | [2-(3,4-Dimethoxy-phenyl)-ethyl]-[4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50 | J Med Chem 40: 125-31 (1997) Article DOI: 10.1021/jm9605647 BindingDB Entry DOI: 10.7270/Q2JQ128M | |||||||||||
More data for this Ligand-Target Pair |
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