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Compile Data Set for Download or QSAR

Found 27 hits of kd data for polymerid = 50000738   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145062
PNG
(1-[12b-hydroxy-1b,3a,10b-trimethyl-2,3,4,5-tetra(m...)
Show SMILES COC(=O)C12O[C@@H]1C(=C)C[C@@]1(O)[C@@H]3CC[C@@]4(C)[C@@H]5C=CC(=O)OC[C@]5(C(C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]4[C@@]3(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@]21C
Show InChI InChI=1S/C40H52O16/c1-18-16-39(48)26-14-15-35(8)25-12-13-27(46)50-17-38(25,19(2)51-20(3)41)31(53-22(5)43)28(52-21(4)42)29(35)36(26,9)32(54-23(6)44)33(55-24(7)45)37(39,10)40(30(18)56-40)34(47)49-11/h12-13,19,25-26,28-33,48H,1,14-17H2,2-11H3/t19?,25-,26+,28-,29-,30+,31-,32+,33-,35-,36-,37+,38+,39+,40?/m0/s1
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n/an/an/a 100n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145061
PNG
(1-{6-[4-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(Oc2cc(C)c(Oc3c(OC)c4occc4c(OC)c3C(C)=O)cc2C)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C32H30O10/c1-15-13-22(42-30-24(18(4)34)26(36-6)20-10-12-40-28(20)32(30)38-8)16(2)14-21(15)41-29-23(17(3)33)25(35-5)19-9-11-39-27(19)31(29)37-7/h9-14H,1-8H3
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n/an/an/a 280n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145050
PNG
(1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-phen...)
Show SMILES COc1c(O)c(C(=O)\C=C\c2ccccc2)c(OC)c2ccoc12
Show InChI InChI=1S/C19H16O5/c1-22-17-13-10-11-24-18(13)19(23-2)16(21)15(17)14(20)9-8-12-6-4-3-5-7-12/h3-11,21H,1-2H3/b9-8+
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n/an/an/a 400n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145055
PNG
(1-{6-[4-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(Oc2cc(C)c(Oc3c(OC)c4occc4c(OC)c3C(C)=O)c(C)c2)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C32H30O10/c1-15-13-19(41-29-22(17(3)33)25(35-5)20-9-11-39-27(20)31(29)37-7)14-16(2)24(15)42-30-23(18(4)34)26(36-6)21-10-12-40-28(21)32(30)38-8/h9-14H,1-8H3
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n/an/an/a 560n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145053
PNG
(1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-phen...)
Show SMILES COc1c(O)c(C(=O)CCc2ccccc2)c(OC)c2ccoc12
Show InChI InChI=1S/C19H18O5/c1-22-17-13-10-11-24-18(13)19(23-2)16(21)15(17)14(20)9-8-12-6-4-3-5-7-12/h3-7,10-11,21H,8-9H2,1-2H3
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n/an/an/a 600n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145049
PNG
(1-{6-[6-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(C(C)=O)c(OCCCCCCOc2c(OC)c3occc3c(OC)c2C(C)=O)c(OC)c2occc12
Show InChI InChI=1S/C30H34O10/c1-17(31)21-23(33-3)19-11-15-39-25(19)29(35-5)27(21)37-13-9-7-8-10-14-38-28-22(18(2)32)24(34-4)20-12-16-40-26(20)30(28)36-6/h11-12,15-16H,7-10,13-14H2,1-6H3
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n/an/an/a 680n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145048
PNG
((E)-1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-...)
Show SMILES COc1c(O)c(C(=O)\C=C\c2cccc(O)c2)c(OC)c2ccoc12
Show InChI InChI=1S/C19H16O6/c1-23-17-13-8-9-25-18(13)19(24-2)16(22)15(17)14(21)7-6-11-4-3-5-12(20)10-11/h3-10,20,22H,1-2H3/b7-6+
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n/an/an/a 700n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145059
PNG
((E)-1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-...)
Show SMILES COc1c(O)c(C(=O)\C=C\c2ccc(C)cc2)c(OC)c2ccoc12
Show InChI InChI=1S/C20H18O5/c1-12-4-6-13(7-5-12)8-9-15(21)16-17(22)20(24-3)19-14(10-11-25-19)18(16)23-2/h4-11,22H,1-3H3/b9-8+
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n/an/an/a 700n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145054
PNG
((E)-1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-...)
Show SMILES COc1cccc(\C=C\C(=O)c2c(O)c(OC)c3occc3c2OC)c1
Show InChI InChI=1S/C20H18O6/c1-23-13-6-4-5-12(11-13)7-8-15(21)16-17(22)20(25-3)19-14(9-10-26-19)18(16)24-2/h4-11,22H,1-3H3/b8-7+
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n/an/an/a 800n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145047
PNG
((E)-3-(4-Bromo-thiophen-2-yl)-1-(6-hydroxy-4,7-dim...)
Show SMILES COc1c(O)c(C(=O)\C=C\c2cc(Br)cs2)c(OC)c2ccoc12
Show InChI InChI=1S/C17H13BrO5S/c1-21-15-11-5-6-23-16(11)17(22-2)14(20)13(15)12(19)4-3-10-7-9(18)8-24-10/h3-8,20H,1-2H3/b4-3+
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n/an/an/a 800n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145056
PNG
(1-{6-[5-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(C(C)=O)c(OCCCCCOc2c(OC)c3occc3c(OC)c2C(C)=O)c(OC)c2occc12
Show InChI InChI=1S/C29H32O10/c1-16(30)20-22(32-3)18-10-14-38-24(18)28(34-5)26(20)36-12-8-7-9-13-37-27-21(17(2)31)23(33-4)19-11-15-39-25(19)29(27)35-6/h10-11,14-15H,7-9,12-13H2,1-6H3
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n/an/an/a 820n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145064
PNG
((E)-1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-...)
Show SMILES COc1c(O)c(C(=O)\C=C\c2cccs2)c(OC)c2ccoc12
Show InChI InChI=1S/C17H14O5S/c1-20-15-11-7-8-22-16(11)17(21-2)14(19)13(15)12(18)6-5-10-4-3-9-23-10/h3-9,19H,1-2H3/b6-5+
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n/an/an/a 1.00E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145046
PNG
(1-{6-[4-(5-Acetyl-4-methoxy-benzofuran-6-yloxymeth...)
Show SMILES COc1c(C(C)=O)c(OCc2ccc(COc3cc4occc4c(OC)c3C(C)=O)cc2)cc2occc12
Show InChI InChI=1S/C30H26O8/c1-17(31)27-25(13-23-21(9-11-35-23)29(27)33-3)37-15-19-5-7-20(8-6-19)16-38-26-14-24-22(10-12-36-24)30(34-4)28(26)18(2)32/h5-14H,15-16H2,1-4H3
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n/an/an/a 1.00E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145069
PNG
(1-(6-Hydroxy-4,7-dimethoxy-2,3-dihydro-benzofuran-...)
Show SMILES COc1c2OCCc2c(OC)c(C(=O)CCc2ccccc2)c1O
Show InChI InChI=1S/C19H20O5/c1-22-17-13-10-11-24-18(13)19(23-2)16(21)15(17)14(20)9-8-12-6-4-3-5-7-12/h3-7,21H,8-11H2,1-2H3
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n/an/an/a 1.50E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145063
PNG
(1-(6-{4-[6-(1-Hydroxy-ethyl)-4,7-dimethoxy-benzofu...)
Show SMILES COc1c(OCc2ccc(COc3c(OC)c4occc4c(OC)c3C(C)O)cc2)c(C(C)O)c(OC)c2occc12
Show InChI InChI=1S/C32H34O10/c1-17(33)23-25(35-3)21-11-13-40-28(21)32(38-6)31(23)42-16-20-9-7-19(8-10-20)15-41-30-24(18(2)34)29(37-5)27-22(12-14-39-27)26(30)36-4/h7-14,17-18,33-34H,15-16H2,1-6H3
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n/an/an/a 2.00E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145067
PNG
(1-{6-[7-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(C(C)=O)c(OCCCCCCCOc2c(OC)c3occc3c(OC)c2C(C)=O)c(OC)c2occc12
Show InChI InChI=1S/C31H36O10/c1-18(32)22-24(34-3)20-12-16-40-26(20)30(36-5)28(22)38-14-10-8-7-9-11-15-39-29-23(19(2)33)25(35-4)21-13-17-41-27(21)31(29)37-6/h12-13,16-17H,7-11,14-15H2,1-6H3
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n/an/an/a 3.00E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145070
PNG
(1-{6-[4-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(OCc2ccc(COc3c(OC)c4occc4c(OC)c3C(C)=O)cc2)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C32H30O10/c1-17(33)23-25(35-3)21-11-13-39-27(21)31(37-5)29(23)41-15-19-7-9-20(10-8-19)16-42-30-24(18(2)34)26(36-4)22-12-14-40-28(22)32(30)38-6/h7-14H,15-16H2,1-6H3
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n/an/an/a 3.10E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145052
PNG
(1-{6-[4-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(C(C)=O)c(OCCCCOc2c(OC)c3occc3c(OC)c2C(C)=O)c(OC)c2occc12
Show InChI InChI=1S/C28H30O10/c1-15(29)19-21(31-3)17-9-13-37-23(17)27(33-5)25(19)35-11-7-8-12-36-26-20(16(2)30)22(32-4)18-10-14-38-24(18)28(26)34-6/h9-10,13-14H,7-8,11-12H2,1-6H3
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n/an/an/a 3.50E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145051
PNG
(1-(6-{2-[2-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yl...)
Show SMILES COc1c(C(C)=O)c(OCCOCCOc2c(OC)c3occc3c(OC)c2C(C)=O)c(OC)c2occc12
Show InChI InChI=1S/C28H30O11/c1-15(29)19-21(31-3)17-7-9-36-23(17)27(33-5)25(19)38-13-11-35-12-14-39-26-20(16(2)30)22(32-4)18-8-10-37-24(18)28(26)34-6/h7-10H,11-14H2,1-6H3
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n/an/an/a 4.00E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145068
PNG
(2,5-Bis-(5-acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(OCc2ccc(COc3c(OC)c4occc4c(OC)c3C(C)=O)c(c2)C(O)=O)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C33H30O12/c1-16(34)23-25(38-3)20-9-11-42-27(20)31(40-5)29(23)44-14-18-7-8-19(22(13-18)33(36)37)15-45-30-24(17(2)35)26(39-4)21-10-12-43-28(21)32(30)41-6/h7-13H,14-15H2,1-6H3,(H,36,37)
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n/an/an/a 5.00E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145065
PNG
(1-{6-[4-(5-Acetyl-4,7-dimethoxy-benzofuran-6-yloxy...)
Show SMILES COc1c(Oc2ccc(Oc3c(OC)c4occc4c(OC)c3C(C)=O)c(C)c2C)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C32H30O10/c1-15-16(2)22(42-30-24(18(4)34)26(36-6)20-12-14-40-28(20)32(30)38-8)10-9-21(15)41-29-23(17(3)33)25(35-5)19-11-13-39-27(19)31(29)37-7/h9-14H,1-8H3
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n/an/an/a 7.10E+3n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145045
PNG
(1-(6-Benzyloxy-4,7-dimethoxy-benzofuran-5-yl)-etha...)
Show SMILES COc1c(OCc2ccccc2)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C19H18O5/c1-12(20)15-16(21-2)14-9-10-23-17(14)19(22-3)18(15)24-11-13-7-5-4-6-8-13/h4-10H,11H2,1-3H3
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n/an/an/a 1.00E+4n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145058
PNG
((E)-1-(6-Hydroxy-4-methoxy-benzofuran-5-yl)-3-phen...)
Show SMILES COc1c(C(=O)\C=C\c2ccccc2)c(O)cc2occc12
Show InChI InChI=1S/C18H14O4/c1-21-18-13-9-10-22-16(13)11-15(20)17(18)14(19)8-7-12-5-3-2-4-6-12/h2-11,20H,1H3/b8-7+
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n/an/an/a 1.70E+4n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145066
PNG
(1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-ethano...)
Show SMILES COc1c(O)c(C(C)=O)c(OC)c2ccoc12
Show InChI InChI=1S/C12H12O5/c1-6(13)8-9(14)12(16-3)11-7(4-5-17-11)10(8)15-2/h4-5,14H,1-3H3
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n/an/an/a 5.00E+4n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145060
PNG
(5-[(1E)-1-[(E)-2-[1-(6-hydroxy-4,7-dimethoxy-1-ben...)
Show SMILES COc1c(O)c(C(C)=NN=C(C)c2c(O)c(OC)c3occc3c2OC)c(OC)c2ccoc12
Show InChI InChI=1S/C24H24N2O8/c1-11(15-17(27)23(31-5)21-13(7-9-33-21)19(15)29-3)25-26-12(2)16-18(28)24(32-6)22-14(8-10-34-22)20(16)30-4/h7-10,27-28H,1-6H3
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n/an/an/a 7.00E+4n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50145057
PNG
(1-(6-Hydroxy-4-methoxy-benzofuran-5-yl)-ethanone |...)
Show SMILES COc1c(C(C)=O)c(O)cc2occc12
Show InChI InChI=1S/C11H10O4/c1-6(12)10-8(13)5-9-7(3-4-15-9)11(10)14-2/h3-5,13H,1-2H3
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n/an/an/a 1.00E+5n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM10458
PNG
(4-AP | 4-Aminopyridine 10 | CHEMBL284348 | DALFAMP...)
Show SMILES Nc1ccncc1
Show InChI InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
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n/an/an/a 1.95E+5n/an/an/an/an/a



Institute of Medical Research Biotechnology Centre

Curated by ChEMBL


Assay Description
Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes


J Med Chem 47: 2326-36 (2004)

More data for this
Ligand-Target Pair