Compile Data Set for Download or QSAR

Found 119 hits of ec50 for UniProtKB: P22443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Rattus norvegicus)	BDBM50014777 (1-Di-p-tolylmethyl-1H-imidazole | CHEMBL135381) Show SMILES Cc1ccc(cc1)C(c1ccc(C)cc1)n1ccnc1 Show InChI InChI=1S/C18H18N2/c1-14-3-7-16(8-4-14)18(20-12-11-19-13-20)17-9-5-15(2)6-10-17/h3-13,18H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014754 (1-[(4-Chloro-phenyl)-(4-methoxy-phenyl)-methyl]-1H...) Show SMILES COc1ccc(cc1)C(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C17H15ClN2O/c1-21-16-8-4-14(5-9-16)17(20-11-10-19-12-20)13-2-6-15(18)7-3-13/h2-12,17H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.40	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014780 (1-[Bis-(4-chloro-phenyl)-methyl]-1H-[1,2,4]triazol...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1cncn1 Show InChI InChI=1S/C15H11Cl2N3/c16-13-5-1-11(2-6-13)15(20-10-18-9-19-20)12-3-7-14(17)8-4-12/h1-10,15H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	8.80	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014773 (1-[Bis-(4-bromo-phenyl)-methyl]-1H-imidazole | CHE...) Show SMILES Brc1ccc(cc1)C(c1ccc(Br)cc1)n1ccnc1 Show InChI InChI=1S/C16H12Br2N2/c17-14-5-1-12(2-6-14)16(20-10-9-19-11-20)13-3-7-15(18)8-4-13/h1-11,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.90	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014803 (4-[Bis-(4-chloro-phenyl)-methyl]-4H-[1,2,4]triazol...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1cnnc1 Show InChI InChI=1S/C15H11Cl2N3/c16-13-5-1-11(2-6-13)15(20-9-18-19-10-20)12-3-7-14(17)8-4-12/h1-10,15H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014776 (1-[bis(4-chlorophenyl)(1H-imidazol-2-yl)methyl]-1H...) Show SMILES Clc1ccc(cc1)C(c1ncc[nH]1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H14Cl2N4/c20-16-5-1-14(2-6-16)19(18-23-9-10-24-18,25-12-11-22-13-25)15-3-7-17(21)8-4-15/h1-13H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	9.40	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014771 (Bis-(4-chloro-phenyl)-thiazol-5-yl-methanol | CHEM...) Show SMILES OC(c1cncs1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11Cl2NOS/c17-13-5-1-11(2-6-13)16(20,15-9-19-10-21-15)12-3-7-14(18)8-4-12/h1-10,20H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	9.60	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014764 (5-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-...) Show SMILES Clc1ccc(cc1)C(c1nnc[nH]1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-5-1-13(2-6-15)18(17-22-11-23-24-17,25-10-9-21-12-25)14-3-7-16(20)8-4-14/h1-12H,(H,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014809 (1-[(4-Chloro-phenyl)-(4-trifluoromethyl-phenyl)-me...) Show SMILES FC(F)(F)c1ccc(cc1)C(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C17H12ClF3N2/c18-15-7-3-13(4-8-15)16(23-10-9-22-11-23)12-1-5-14(6-2-12)17(19,20)21/h1-11,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014796 (1-[(4-Methoxy-phenyl)-p-tolyl-methyl]-1H-imidazole...) Show SMILES COc1ccc(cc1)C(c1ccc(C)cc1)n1ccnc1 Show InChI InChI=1S/C18H18N2O/c1-14-3-5-15(6-4-14)18(20-12-11-19-13-20)16-7-9-17(21-2)10-8-16/h3-13,18H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014763 (4-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-...) Show SMILES Clc1ccc(cc1)C(c1cn[nH]c1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H14Cl2N4/c20-17-5-1-14(2-6-17)19(16-11-23-24-12-16,25-10-9-22-13-25)15-3-7-18(21)8-4-15/h1-13H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014755 (1-[Bis-(4-methoxy-phenyl)-methyl]-1H-imidazole | C...) Show SMILES COc1ccc(cc1)C(c1ccc(OC)cc1)n1ccnc1 Show InChI InChI=1S/C18H18N2O2/c1-21-16-7-3-14(4-8-16)18(20-12-11-19-13-20)15-5-9-17(22-2)10-6-15/h3-13,18H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014800 (1-[bis(4-chlorophenyl)(1H-imidazol-4-yl)methyl]-1H...) Show SMILES Clc1ccc(cc1)C(c1cnc[nH]1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H14Cl2N4/c20-16-5-1-14(2-6-16)19(18-11-23-12-24-18,25-10-9-22-13-25)15-3-7-17(21)8-4-15/h1-13H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014759 (5-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-thi...) Show SMILES Clc1ccc(cc1)C(c1cncs1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H13Cl2N3S/c20-16-5-1-14(2-6-16)19(18-11-23-13-25-18,24-10-9-22-12-24)15-3-7-17(21)8-4-15/h1-13H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014814 (4-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-...) Show SMILES Clc1ccc(cc1)C(c1cnn[nH]1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-5-1-13(2-6-15)18(17-11-22-24-23-17,25-10-9-21-12-25)14-3-7-16(20)8-4-14/h1-12H,(H,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014804 (Bis-(4-chloro-phenyl)-isothiazol-5-yl-methanol | C...) Show SMILES OC(c1ccns1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11Cl2NOS/c17-13-5-1-11(2-6-13)16(20,15-9-10-19-21-15)12-3-7-14(18)8-4-12/h1-10,20H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014782 (1-[Bis-(4-chloro-phenyl)-methyl]-1H-[1,2,3]triazol...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1ccnn1 Show InChI InChI=1S/C15H11Cl2N3/c16-13-5-1-11(2-6-13)15(20-10-9-18-19-20)12-3-7-14(17)8-4-12/h1-10,15H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014808 (1-[(4-Chloro-phenyl)-phenyl-methyl]-1H-imidazole |...) Show SMILES Clc1ccc(cc1)C(c1ccccc1)n1ccnc1 Show InChI InChI=1S/C16H13ClN2/c17-15-8-6-14(7-9-15)16(19-11-10-18-12-19)13-4-2-1-3-5-13/h1-12,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014775 (5-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-pyr...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)(c1cncnc1)n1ccnc1 Show InChI InChI=1S/C20H14Cl2N4/c21-18-5-1-15(2-6-18)20(26-10-9-23-14-26,17-11-24-13-25-12-17)16-3-7-19(22)8-4-16/h1-14H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014785 (Bis-(4-chloro-phenyl)-(1H-imidazol-4-yl)-methanol ...) Show SMILES OC(c1cnc[nH]1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2O/c17-13-5-1-11(2-6-13)16(21,15-9-19-10-20-15)12-3-7-14(18)8-4-12/h1-10,21H,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014783 (2-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-pyr...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)(c1ccccn1)n1ccnc1 Show InChI InChI=1S/C21H15Cl2N3/c22-18-8-4-16(5-9-18)21(26-14-13-24-15-26,20-3-1-2-12-25-20)17-6-10-19(23)11-7-17/h1-15H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014778 (Bis-(4-chloro-phenyl)-(1H-pyrazol-4-yl)-methanol |...) Show SMILES OC(c1cn[nH]c1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2O/c17-14-5-1-11(2-6-14)16(21,13-9-19-20-10-13)12-3-7-15(18)8-4-12/h1-10,21H,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014810 (1-[Bis-(4-nitro-phenyl)-methyl]-1H-imidazole | CHE...) Show SMILES [O-][N+](=O)c1ccc(cc1)C(c1ccc(cc1)[N+]([O-])=O)n1ccnc1 Show InChI InChI=1S/C16H12N4O4/c21-19(22)14-5-1-12(2-6-14)16(18-10-9-17-11-18)13-3-7-15(8-4-13)20(23)24/h1-11,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014797 (1-[Bis-(4-fluoro-phenyl)-methyl]-1H-imidazole | CH...) Show SMILES Fc1ccc(cc1)C(c1ccc(F)cc1)n1ccnc1 Show InChI InChI=1S/C16H12F2N2/c17-14-5-1-12(2-6-14)16(20-10-9-19-11-20)13-3-7-15(18)8-4-13/h1-11,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014756 (1-[Bis-(4-chloro-phenyl)-methyl]-1H-imidazole | CH...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C16H12Cl2N2/c17-14-5-1-12(2-6-14)16(20-10-9-19-11-20)13-3-7-15(18)8-4-13/h1-11,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50367548 (CHEMBL1794921) Show SMILES Clc1ccc(cc1)C(C1=CN=CNC1)c1ccc(Cl)cc1 |c:11,t:9| Show InChI InChI=1S/C17H14Cl2N2/c18-15-5-1-12(2-6-15)17(14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-9,11,17H,10H2,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014750 (3-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-pyr...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)(c1cccnc1)n1ccnc1 Show InChI InChI=1S/C21H15Cl2N3/c22-19-7-3-16(4-8-19)21(26-13-12-25-15-26,18-2-1-11-24-14-18)17-5-9-20(23)10-6-17/h1-15H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014802 (4-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-pyr...) Show SMILES Clc1ccc(cc1)C(c1ccncc1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C21H15Cl2N3/c22-19-5-1-16(2-6-19)21(26-14-13-25-15-26,18-9-11-24-12-10-18)17-3-7-20(23)8-4-17/h1-15H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014324 (5-[Bis-(4-chloro-phenyl)-methyl]-pyrimidine | 5-[B...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H12Cl2N2/c18-15-5-1-12(2-6-15)17(14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,17H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014324 (5-[Bis-(4-chloro-phenyl)-methyl]-pyrimidine | 5-[B...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H12Cl2N2/c18-15-5-1-12(2-6-15)17(14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,17H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014793 (5-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-iso...) Show SMILES Clc1ccc(cc1)C(c1ccns1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H13Cl2N3S/c20-16-5-1-14(2-6-16)19(18-9-10-23-25-18,24-12-11-22-13-24)15-3-7-17(21)8-4-15/h1-13H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014749 (3-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-1H-...) Show SMILES Clc1ccc(cc1)C(c1ccn[nH]1)(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H14Cl2N4/c20-16-5-1-14(2-6-16)19(18-9-10-23-24-18,25-12-11-22-13-25)15-3-7-17(21)8-4-15/h1-13H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014781 (1-[(2-Methoxy-phenyl)-phenyl-methyl]-1H-imidazole ...) Show SMILES COc1ccccc1C(c1ccccc1)n1ccnc1 Show InChI InChI=1S/C17H16N2O/c1-20-16-10-6-5-9-15(16)17(19-12-11-18-13-19)14-7-3-2-4-8-14/h2-13,17H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50024481 ((4-Chloro-phenyl)-pyrimidin-5-yl-(4-trifluoromethy...) Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(cc1)C(F)(F)F)c1cncnc1 Show InChI InChI=1S/C18H12ClF3N2O/c19-16-7-5-13(6-8-16)17(25,15-9-23-11-24-10-15)12-1-3-14(4-2-12)18(20,21)22/h1-11,25H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014815 (Bis-(4-chloro-phenyl)-pyrimidin-5-yl-methanol | CH...) Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H12Cl2N2O/c18-15-5-1-12(2-6-15)17(22,14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,22H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014815 (Bis-(4-chloro-phenyl)-pyrimidin-5-yl-methanol | CH...) Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H12Cl2N2O/c18-15-5-1-12(2-6-15)17(22,14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,22H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014752 (1-[Bis-(2-chloro-phenyl)-methyl]-1H-imidazole | CH...) Show SMILES Clc1ccccc1C(c1ccccc1Cl)n1ccnc1 Show InChI InChI=1S/C16H12Cl2N2/c17-14-7-3-1-5-12(14)16(20-10-9-19-11-20)13-6-2-4-8-15(13)18/h1-11,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50024516 (5-[Bis-(4-chloro-phenyl)-fluoro-methyl]-pyrimidine...) Show SMILES FC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H11Cl2FN2/c18-15-5-1-12(2-6-15)17(20,14-9-21-11-22-10-14)13-3-7-16(19)8-4-13/h1-11H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50024524 (5-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyrimidine | C...) Show SMILES CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C18H14Cl2N2/c1-18(15-10-21-12-22-11-15,13-2-6-16(19)7-3-13)14-4-8-17(20)9-5-14/h2-12H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014794 (3-[Bis-(4-chloro-phenyl)-methyl]-pyridine | CHEMBL...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C18H13Cl2N/c19-16-7-3-13(4-8-16)18(15-2-1-11-21-12-15)14-5-9-17(20)10-6-14/h1-12,18H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014798 (Bis-(4-chloro-phenyl)-pyridin-4-yl-methanol | CHEM...) Show SMILES OC(c1ccncc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H13Cl2NO/c19-16-5-1-13(2-6-16)18(22,15-9-11-21-12-10-15)14-3-7-17(20)8-4-14/h1-12,22H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014791 (Bis-(4-chloro-phenyl)-(1H-pyrazol-3-yl)-methanol |...) Show SMILES OC(c1ccn[nH]1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H12Cl2N2O/c17-13-5-1-11(2-6-13)16(21,15-9-10-19-20-15)12-3-7-14(18)8-4-12/h1-10,21H,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014774 (Bis-(4-chloro-phenyl)-pyrazin-2-yl-methanol | CHEM...) Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cnccn1 Show InChI InChI=1S/C17H12Cl2N2O/c18-14-5-1-12(2-6-14)17(22,16-11-20-9-10-21-16)13-3-7-15(19)8-4-13/h1-11,22H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014788 (1-Benzhydryl-1H-imidazole | CHEMBL336638) Show SMILES c1cn(cn1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C16H14N2/c1-3-7-14(8-4-1)16(18-12-11-17-13-18)15-9-5-2-6-10-15/h1-13,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50024513 (6-Acetylsulfanyl-8-[2-[(4-amino-2-methyl-pyrimidin...) Show SMILES COC(=O)CCCCC(CCSS\C(CCO)=C(/C)N(Cc1cnc(C)nc1N)C=O)SC(C)=O Show InChI InChI=1S/C23H36N4O5S3/c1-16(27(15-29)14-19-13-25-17(2)26-23(19)24)21(9-11-28)35-33-12-10-20(34-18(3)30)7-5-6-8-22(31)32-4/h13,15,20,28H,5-12,14H2,1-4H3,(H2,24,25,26)/b21-16+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014751 (3-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyridine | CHE...) Show SMILES CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C19H15Cl2N/c1-19(16-3-2-12-22-13-16,14-4-8-17(20)9-5-14)15-6-10-18(21)11-7-15/h2-13H,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	145	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014786 (2-[Bis-(4-chloro-phenyl)-methyl]-2H-tetrazole | CH...) Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1ncnn1 Show InChI InChI=1S/C14H10Cl2N4/c15-12-5-1-10(2-6-12)14(20-18-9-17-19-20)11-3-7-13(16)8-4-11/h1-9,14H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014758 (Bis-(4-chloro-phenyl)-pyridin-3-yl-methanol | CHEM...) Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C18H13Cl2NO/c19-16-7-3-13(4-8-16)18(22,15-2-1-11-21-12-15)14-5-9-17(20)10-6-14/h1-12,22H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50014801 (4-[Bis-(4-chloro-phenyl)-methyl]-pyridine; hydroch...) Show SMILES Clc1ccc(cc1)C(c1ccncc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H13Cl2N/c19-16-5-1-13(2-6-16)18(15-9-11-21-12-10-15)14-3-7-17(20)8-4-14/h1-12,18H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair
Aromatase (Rattus norvegicus)	BDBM50024522 ((4-Chloro-phenyl)-(4-fluoro-phenyl)-pyrimidin-5-yl...) Show SMILES OC(c1ccc(F)cc1)(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H12ClFN2O/c18-15-5-1-12(2-6-15)17(22,14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,22H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair

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