BindingDB PrimarySearch

Found 6 hits of ki data for polymerid = 50001218
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CAD protein (Homo sapiens (Human))	BDBM50010599 (6-Mercaptomethyl-2-oxo-2,3,4,5-tetrahydro-pyrimidi...) Show SMILES OC(=O)C1CC(NC(=O)N1)C=S Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Mayo Clinic & Foundation Curated by ChEMBL					Assay Description Inhibitory activity against Dihydroorotase (DHO) at pH 7.4 and 8.5				J Med Chem 33: 819-23 (1990) BindingDB Entry DOI: 10.7270/Q2ZC81VR
Mayo Clinic & Foundation Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50020110 ((4S,6R)-6-Mercaptomethyl-2-oxo-hexahydro-pyrimidin...) Show SMILES OC(=O)[C@@H]1C[C@H](CS)NC(=O)N1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50291969 ((2R,4S)-4-Mercapto-4,6-dioxo-4lambda5-[1,4]azaph...) Show SMILES OC(=O)[C@H]1NC(=O)CP(O)(S)=C1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50291969 ((2R,4S)-4-Mercapto-4,6-dioxo-4lambda5-[1,4]azaph...) Show SMILES OC(=O)[C@H]1NC(=O)CP(O)(S)=C1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50067883 (4-Hydroxy-4,6-dioxo-4lambda5-[1,4]azaphosphinane...) Show SMILES OC(=O)C1NC(=O)CP(O)(O)=C1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.				J Med Chem 41: 4550-5 (1998) Article DOI: 10.1021/jm970814z BindingDB Entry DOI: 10.7270/Q26D5S58
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
CAD protein (Homo sapiens (Human))	BDBM50010600 (CHEMBL168878 \| Ethyl-3-borono-2-(carbamylamino)pro...) Show SMILES CCOC(=O)C(CB(O)O)NC(N)=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Mayo Clinic & Foundation Curated by ChEMBL					Assay Description Inhibitory activity against Dihydroorotase (DHO) at pH 6.0				J Med Chem 33: 819-23 (1990) BindingDB Entry DOI: 10.7270/Q2ZC81VR
Mayo Clinic & Foundation Curated by ChEMBL					More data for this Ligand-Target Pair