Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271230 (US10059720, Example 45 | US10975091, Example 45) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271230 (US10059720, Example 45 | US10975091, Example 45) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271257 (US10059720, Example 72 | US10975091, Example 72) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271257 (US10059720, Example 72 | US10975091, Example 72) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271275 (US10059720, Example 90 | US10975091, Example 90) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271275 (US10059720, Example 90 | US10975091, Example 90) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271198 (US10059720, Example 13 | US10975091, Example 13) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271198 (US10059720, Example 13 | US10975091, Example 13) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271277 (US10059720, Example 92 | US10975091, Example 92) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271277 (US10059720, Example 92 | US10975091, Example 92) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271190 (US10059720, Example 6 | US10975091, Example 6) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271330 (US10059720, Example 145 | US10975091, Example 145) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271272 (US10059720, Example 87 | US10975091, Example 87) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271330 (US10059720, Example 145 | US10975091, Example 145) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271190 (US10059720, Example 6 | US10975091, Example 6) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271272 (US10059720, Example 87 | US10975091, Example 87) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271288 (US10059720, Example 103 | US10975091, Example 103) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271288 (US10059720, Example 103 | US10975091, Example 103) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271218 (US10059720, Example 33 | US10975091, Example 33) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271280 (US10059720, Example 95 | US10975091, Example 95) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271232 (US10059720, Example 47 | US10975091, Example 47) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271280 (US10059720, Example 95 | US10975091, Example 95) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271218 (US10059720, Example 33 | US10975091, Example 33) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271232 (US10059720, Example 47 | US10975091, Example 47) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271245 (US10059720, Example 60 | US10975091, Example 60) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271233 (US10059720, Example 48 | US10975091, Example 48) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271245 (US10059720, Example 60 | US10975091, Example 60) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM401355 (US10005762, Example 35) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271233 (US10059720, Example 48 | US10975091, Example 48) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271258 (US10059720, Example 73 | US10975091, Example 73) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271258 (US10059720, Example 73 | US10975091, Example 73) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271229 (US10059720, Example 44 | US10975091, Example 44) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271252 (US10059720, Example 67 | US10975091, Example 67) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271246 (US10059720, Example 61 | US10975091, Example 61) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM401368 (US10005762, Example 48) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271252 (US10059720, Example 67 | US10975091, Example 67) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271246 (US10059720, Example 61 | US10975091, Example 61) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271229 (US10059720, Example 44 | US10975091, Example 44) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271210 (US10059720, Example 25 | US10975091, Example 25) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271210 (US10059720, Example 25 | US10975091, Example 25) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271290 (US10059720, Example 105 | US10975091, Example 105) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271211 (US10059720, Example 26 | US10975091, Example 26) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271211 (US10059720, Example 26 | US10975091, Example 26) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271290 (US10059720, Example 105 | US10975091, Example 105) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271241 (US10059720, Example 56 | US10975091, Example 56) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM50245396 (CHEMBL4101200) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens Curated by ChEMBL | Assay Description Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assay | J Med Chem 59: 9107-9123 (2016) Article DOI: 10.1021/acs.jmedchem.6b01031 BindingDB Entry DOI: 10.7270/Q2PK0JJG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271241 (US10059720, Example 56 | US10975091, Example 56) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM401389 (US10005762, Example 69) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w... | Bioorg Med Chem 17: 7933-48 (2009) BindingDB Entry DOI: 10.7270/Q2PG1V3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271240 (US10059720, Example 55 | US10975091, Example 55) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent | Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult... | US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human)) | BDBM271240 (US10059720, Example 55 | US10975091, Example 55) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent | Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100... | US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR | |||||||||||
More data for this Ligand-Target Pair |
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