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Compile Data Set for Download or QSAR

Found 4 hits of ki data for polymerid = 50001391,50002414   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptidyl-glycine alpha-amidating monooxygenase


(Homo sapiens (Human))
BDBM50288771
PNG
(((E)-Styrylsulfanyl)-acetic acid | CHEMBL127222)
Show SMILES OC(=O)CS\C=C\c1ccccc1
Show InChI InChI=1S/C10H10O2S/c11-10(12)8-13-7-6-9-4-2-1-3-5-9/h1-7H,8H2,(H,11,12)/b7-6+
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
0.100n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for inhibition of peptidylglycine alpha hydroxylating monooxygenase (PHM) was determined


Bioorg Med Chem Lett 6: 393-396 (1996)

More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Homo sapiens (Human))
BDBM50288770
PNG
(CHEMBL335660 | Phenylethynylsulfanyl-acetic acid)
Show SMILES OC(=O)CSC#Cc1ccccc1
Show InChI InChI=1S/C10H8O2S/c11-10(12)8-13-7-6-9-4-2-1-3-5-9/h1-5H,8H2,(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
0.190n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for inhibition of peptidylglycine alpha hydroxylating monooxygenase (PHM) was determined


Bioorg Med Chem Lett 6: 393-396 (1996)

More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Rattus norvegicus)
BDBM50273316
PNG
(CHEMBL509495 | N-dansyl-Tyr-Val-D-Ala)
Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)N[C@H](C)C(O)=O
Show InChI InChI=1S/C29H36N4O7S/c1-17(2)26(28(36)30-18(3)29(37)38)31-27(35)23(16-19-12-14-20(34)15-13-19)32-41(39,40)25-11-7-8-21-22(25)9-6-10-24(21)33(4)5/h6-15,17-18,23,26,32,34H,16H2,1-5H3,(H,30,36)(H,31,35)(H,37,38)/t18-,23+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.70E+5n/an/an/an/an/an/an/an/a



University of South Florida

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase assessed as inhibition of N-dansyl-Tyr-Val-Gly amidation


Bioorg Med Chem 16: 10061-74 (2008)

More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Rattus norvegicus)
BDBM50273962
PNG
(CHEMBL445286 | Phenylthioacetylglycine)
Show SMILES OC(=O)CNC(=S)Cc1ccccc1
Show InChI InChI=1S/C10H11NO2S/c12-10(13)7-11-9(14)6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.80E+6n/an/an/an/an/an/an/an/a



University of South Florida

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant peptidylglycine alpha-amidating monooxygenase assessed as inhibition of N-dansyl-Tyr-Val-Gly amidation


Bioorg Med Chem 16: 10061-74 (2008)

More data for this
Ligand-Target Pair