Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydropteridine reductase (Rattus norvegicus) | BDBM50025881 (4-(3,4-Dihydroxy-phenyl)-1-methyl-pyridinium; brom...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Noncompetitive Inhibitory activity against rat striatal synaptosomal DHPR enzyme | J Med Chem 28: 311-7 (1985) BindingDB Entry DOI: 10.7270/Q2XK8DKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydropteridine reductase (Rattus norvegicus) | BDBM50025878 (4-(1-Methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-benze...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against Dihydrofolate reductase of rat liver | J Med Chem 28: 311-7 (1985) BindingDB Entry DOI: 10.7270/Q2XK8DKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydropteridine reductase (Rattus norvegicus) | BDBM50025880 (4-(1-Methyl-piperidin-4-yl)-benzene-1,2-diol | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against Dihydrofolate reductase of rat liver | J Med Chem 28: 311-7 (1985) BindingDB Entry DOI: 10.7270/Q2XK8DKG | |||||||||||
More data for this Ligand-Target Pair |