Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079023 (2-Amino-5-(2-phosphono-acetylamino)-pentanoic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079023 (2-Amino-5-(2-phosphono-acetylamino)-pentanoic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079023 (2-Amino-5-(2-phosphono-acetylamino)-pentanoic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079020 ((Aminomethyl-hydroxy-phosphinoylmethyl)-phosphonic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079022 (HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079020 ((Aminomethyl-hydroxy-phosphinoylmethyl)-phosphonic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079019 (2-Amino-5-[(hydroxy-phosphonomethyl-phosphinoylmet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079019 (2-Amino-5-[(hydroxy-phosphonomethyl-phosphinoylmet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079020 ((Aminomethyl-hydroxy-phosphinoylmethyl)-phosphonic...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079022 (HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079021 ((2S)-2-[(tert-butoxycarbonyl)amino]-5-[({[(hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079019 (2-Amino-5-[(hydroxy-phosphonomethyl-phosphinoylmet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.90E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079022 (HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079021 ((2S)-2-[(tert-butoxycarbonyl)amino]-5-[({[(hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079025 ((2S)-2-ammonio-4-[({[(hydroxyphosphinato)methyl]ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079025 ((2S)-2-ammonio-4-[({[(hydroxyphosphinato)methyl]ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50162816 (CHEMBL180570 | Medronic acid | Methylene diphsphon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079021 ((2S)-2-[(tert-butoxycarbonyl)amino]-5-[({[(hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50162816 (CHEMBL180570 | Medronic acid | Methylene diphsphon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50162816 (CHEMBL180570 | Medronic acid | Methylene diphsphon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine transcarbamylase, mitochondrial (Homo sapiens (Human)) | BDBM50079025 ((2S)-2-ammonio-4-[({[(hydroxyphosphinato)methyl]ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair |