Compile Data Set for Download or QSAR

Found 5 hits of kd data for polymerid = 50002080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50385498 (CHEMBL2040551) Show SMILES OC(=O)C(=O)CC(=O)C1(Cc2ccc(Cl)cc2)CCN(CC1)C(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 |(18.46,-2.91,;17.13,-3.68,;17.13,-5.22,;15.79,-2.91,;15.79,-1.37,;14.46,-3.68,;13.13,-2.91,;13.13,-1.37,;11.79,-3.68,;12.73,-4.9,;12.73,-6.44,;11.4,-7.21,;11.4,-8.75,;12.73,-9.52,;12.73,-11.06,;14.06,-8.75,;14.06,-7.21,;10.86,-4.9,;9.33,-4.7,;8.74,-3.28,;9.68,-2.06,;11.2,-2.26,;7.21,-3.08,;6.28,-4.3,;6.62,-1.66,;7.56,-.43,;6.97,.99,;5.44,1.19,;4.51,-.03,;5.1,-1.45,;2.97,-.03,;1.54,.56,;3.17,-1.56,;4.86,2.61,;5.79,3.83,;7.32,3.63,;8.26,4.86,;7.67,6.28,;8.61,7.5,;6.14,6.48,;5.2,5.26,;3.68,5.46,;2.74,4.24,;1.21,4.44,;.28,3.22,;-1.25,3.42,;.86,1.79,;2.39,1.59,;3.33,2.81,)| Show InChI InChI=1S/C37H28ClNO10/c38-22-4-1-20(2-5-22)19-37(32(43)18-29(42)36(47)48)11-13-39(14-12-37)34(44)21-3-8-25(28(15-21)35(45)46)33-26-9-6-23(40)16-30(26)49-31-17-24(41)7-10-27(31)33/h1-10,15-17,40H,11-14,18-19H2,(H,45,46)(H,47,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center Curated by ChEMBL					Assay Description Binding affinity to PA N-terminal domain (Direct)				ACS Chem Biol 7: 526-34 (2012) Article DOI: 10.1021/cb200439z BindingDB Entry DOI: 10.7270/Q2JQ121G
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50508954 (CHEMBL4217762) Show SMILES O=C1N\C(S\C1=C1/C(=O)Nc2ccccc12)=N/N=C1/C(=O)Nc2ccccc12 Show InChI InChI=1S/C19H11N5O3S/c25-16-13(9-5-1-3-7-11(9)20-16)15-18(27)22-19(28-15)24-23-14-10-6-2-4-8-12(10)21-17(14)26/h1-8H,(H,20,25)(H,21,23,26)(H,22,24,27)/b15-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
Shionogi & Company Curated by ChEMBL					Assay Description Binding affinity to Influenza A virus CEN expressed in Escherichia coli by isothermal titration calorimetry				J Med Chem 62: 8101-8114 (2019) Article DOI: 10.1021/acs.jmedchem.9b00861 BindingDB Entry DOI: 10.7270/Q2K35XZJ
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Binding affinity to PA cavity of recombinant Influenza A virus A/PR/8/34(H1N1) PA (239 to 716 residues) measured after 2 mins by SPR analysis				J Med Chem 59: 7699-718 (2016) Article DOI: 10.1021/acs.jmedchem.5b01474 BindingDB Entry DOI: 10.7270/Q21C1ZTF
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50190646 (Finaplix | RU-1697 | Trenbolone | Trenbolone Aceta...) Show SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CCC4=C3C=C[C@]12C)OC(C)=O |c:17,20,t:10| Show InChI InChI=1S/C20H24O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h9-11,17-19H,3-8H2,1-2H3/t17-,18+,19+,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.07E+4	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Binding affinity to PA cavity of recombinant Influenza A virus A/PR/8/34(H1N1) PA (239 to 716 residues) measured after 2 mins by SPR analysis				J Med Chem 59: 7699-718 (2016) Article DOI: 10.1021/acs.jmedchem.5b01474 BindingDB Entry DOI: 10.7270/Q21C1ZTF
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50088493 (Diclazuril | R-64433) Show SMILES Clc1ccc(cc1)C(C#N)c1c(Cl)cc(cc1Cl)-n1ncc(=O)[nH]c1=O Show InChI InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Binding affinity to PA cavity of recombinant Influenza A virus A/PR/8/34(H1N1) PA (239 to 716 residues) measured after 2 mins by SPR analysis				J Med Chem 59: 7699-718 (2016) Article DOI: 10.1021/acs.jmedchem.5b01474 BindingDB Entry DOI: 10.7270/Q21C1ZTF
					More data for this Ligand-Target Pair