BindingDB PrimarySearch

Found 14 hits of ic50 for UniProtKB: P04278
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Research Group Curated by ChEMBL					Assay Description Inhibition of hSHBG (human sex hormone binding globulin )				J Med Chem 33: 129-32 (1990) BindingDB Entry DOI: 10.7270/Q2FJ2HDH
Sterling Research Group Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM8885 ((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human SHBG				J Med Chem 49: 7466-78 (2006) Article DOI: 10.1021/jm060961+ BindingDB Entry DOI: 10.7270/Q23X87G2
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human SHBG				J Med Chem 49: 7466-78 (2006) Article DOI: 10.1021/jm060961+ BindingDB Entry DOI: 10.7270/Q23X87G2
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50200091 (8-hydroxy-7a-methyl-4,5,5a,5b,6,7,7a,8,9,10,10a,10...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human SHBG				J Med Chem 49: 7466-78 (2006) Article DOI: 10.1021/jm060961+ BindingDB Entry DOI: 10.7270/Q23X87G2
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50240916 ((-)-3,4-divanillyltetrahydrofuran \| (3R,4R)-3,4-Bi...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Bayreuth Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human serum SHBG				J Nat Prod 61: 119-21 (1998) Article DOI: 10.1021/np9701743 BindingDB Entry DOI: 10.7270/Q25M66M6
Universit£t Bayreuth Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50200092 (4-(4-(3-fluoro-4-hydroxyphenyl)hexan-3-yl)benzene-...) Show SMILES CCC(C(CC)c1ccc(O)c(F)c1)c1ccc(O)c(O)c1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human SHBG				J Med Chem 49: 7466-78 (2006) Article DOI: 10.1021/jm060961+ BindingDB Entry DOI: 10.7270/Q23X87G2
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50200093 (2-(4-hydroxyphenyl)-1-propyl-2,3-dihydro-1H-inden-...) Show SMILES CCCC1C(Cc2cc(O)ccc12)c1ccc(O)cc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human SHBG				J Med Chem 49: 7466-78 (2006) Article DOI: 10.1021/jm060961+ BindingDB Entry DOI: 10.7270/Q23X87G2
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50166034 (1-(2,4-Dihydroxy-phenyl)-2-(4-hydroxy-phenyl)-etha...) Show SMILES Oc1ccc(CC(=O)c2ccc(O)cc2O)cc1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)				J Med Chem 48: 3203-13 (2005) Article DOI: 10.1021/jm049087f BindingDB Entry DOI: 10.7270/Q2J67GFX
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50166033 (4-((1S,2S,5S,6S,9R)-5-Hydroxymethyl-6,8,9-trimethy...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)				J Med Chem 48: 3203-13 (2005) Article DOI: 10.1021/jm049087f BindingDB Entry DOI: 10.7270/Q2J67GFX
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50200090 (4-(4-hydroxy-3-(hydroxymethyl)-5-methylbenzyl)-2-(...) Show SMILES Cc1cc(Cc2cc(C)c(O)c(CO)c2)cc(CO)c1O Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human SHBG				J Med Chem 49: 7466-78 (2006) Article DOI: 10.1021/jm060961+ BindingDB Entry DOI: 10.7270/Q23X87G2
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50240921 ((-)-matairesinol \| (2R,3R)-2,3-Bis(4-hydroxy-3-met...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Bayreuth Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human serum SHBG				J Nat Prod 61: 119-21 (1998) Article DOI: 10.1021/np9701743 BindingDB Entry DOI: 10.7270/Q25M66M6
Universit£t Bayreuth Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50166035 (4-((1R,2R,5R,6R,9R)-5-Hydroxymethyl-6,8,9-trimethy...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)				J Med Chem 48: 3203-13 (2005) Article DOI: 10.1021/jm049087f BindingDB Entry DOI: 10.7270/Q2J67GFX
University of British Columbia Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50250505 ((-)-(2R,3R)-Secoisolariciresinol \| (-)-secoisolari...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Bayreuth Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human serum SHBG				J Nat Prod 61: 119-21 (1998) Article DOI: 10.1021/np9701743 BindingDB Entry DOI: 10.7270/Q25M66M6
Universit£t Bayreuth Curated by ChEMBL					More data for this Ligand-Target Pair
Sex hormone-binding globulin (Homo sapiens (Human))	BDBM50250487 ((+/-)-enterolactone \| CHEMBL465152) Show SMILES Oc1cccc(CC2COC(=O)C2Cc2cccc(O)c2)c1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Bayreuth Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human serum SHBG				J Nat Prod 61: 119-21 (1998) Article DOI: 10.1021/np9701743 BindingDB Entry DOI: 10.7270/Q25M66M6
Universit£t Bayreuth Curated by ChEMBL					More data for this Ligand-Target Pair