Found 26 hits of ic50 for UniProtKB: Q64602 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386308
(CHEMBL2047861)Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-5-3-7(11)9(13)12(14)8(5)4-6/h1-2,4,7,14H,3,11H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386310
(CHEMBL2049092)Show InChI InChI=1S/C10H12N2O3/c1-15-7-3-2-6-4-8(11)10(13)12(14)9(6)5-7/h2-3,5,8,14H,4,11H2,1H3/t8-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386311
(CHEMBL2049093)Show InChI InChI=1S/C9H9ClN2O2/c10-6-1-2-8-5(3-6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 258 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386292
(CHEMBL2047851)Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 263 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386309
(CHEMBL2047862)Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-7-5-8(11)10(13)12(14)9(7)4-6/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 368 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386312
(CHEMBL2049094)Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-9-7(4-6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 402 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386294
(CHEMBL2049095)Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-1-2-8-5(3-6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 488 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386303
(CHEMBL2047856)Show InChI InChI=1S/C9H9FN2O2/c10-6-3-1-2-5-4-7(11)9(13)12(14)8(5)6/h1-3,7,14H,4,11H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50324539
((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)Show SMILES C[C@H]1COc2c(N3CCN(N)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O |r| Show InChI InChI=1S/C17H19FN4O4/c1-9-8-26-16-13-10(15(23)11(17(24)25)7-22(9)13)6-12(18)14(16)20-2-4-21(19)5-3-20/h6-7,9H,2-5,8,19H2,1H3,(H,24,25)/t9-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Piemonte Orientale Amedeo Avogadro
Curated by ChEMBL
| Assay Description Inhibition of rat brain KAT2 |
J Med Chem 53: 5684-9 (2010)
Article DOI: 10.1021/jm100464k BindingDB Entry DOI: 10.7270/Q2HM58N6 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50324539
((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)Show SMILES C[C@H]1COc2c(N3CCN(N)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O |r| Show InChI InChI=1S/C17H19FN4O4/c1-9-8-26-16-13-10(15(23)11(17(24)25)7-22(9)13)6-12(18)14(16)20-2-4-21(19)5-3-20/h6-7,9H,2-5,8,19H2,1H3,(H,24,25)/t9-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Colorado College
Curated by ChEMBL
| Assay Description Inhibition of rat KAT-2 |
J Med Chem 58: 8762-82 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00461 BindingDB Entry DOI: 10.7270/Q2C82C3F |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386299
(CHEMBL2047852)Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386302
(CHEMBL2047855)Show InChI InChI=1S/C10H12N2O2/c1-6-7-4-2-3-5-8(7)12(14)10(13)9(6)11/h2-6,9,14H,11H2,1H3/t6-,9-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386295
(CHEMBL2049096)Show InChI InChI=1S/C9H9FN2O2/c10-6-2-1-3-8-5(6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386298
(CHEMBL2049099)Show InChI InChI=1S/C10H12N2O3/c1-15-9-4-2-3-8-6(9)5-7(11)10(13)12(8)14/h2-4,7,14H,5,11H2,1H3/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386307
(CHEMBL2047860)Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-3-1-2-5-4-7(14)9(16)15(17)8(5)6/h1-3,7,17H,4,14H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >6.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386296
(CHEMBL2049097)Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-3-8-5(6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >7.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386306
(CHEMBL2047859)Show InChI InChI=1S/C10H12N2O2/c1-6-3-2-4-7-5-8(11)10(13)12(14)9(6)7/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386304
(CHEMBL2047857)Show InChI InChI=1S/C10H12N2O3/c1-15-8-4-2-3-6-5-7(11)10(13)12(14)9(6)8/h2-4,7,14H,5,11H2,1H3/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386301
(CHEMBL2047854)Show InChI InChI=1S/C10H12N2O2/c1-10(11)6-7-4-2-3-5-8(7)12(14)9(10)13/h2-5,14H,6,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386300
(CHEMBL2047853)Show InChI InChI=1S/C10H12N2O2/c1-14-12-9-5-3-2-4-7(9)6-8(11)10(12)13/h2-5,8H,6,11H2,1H3/t8-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386293
(CHEMBL2049100)Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-2-1-3-8-5(6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386305
(CHEMBL2047858)Show InChI InChI=1S/C9H9ClN2O2/c10-6-3-1-2-5-4-7(11)9(13)12(14)8(5)6/h1-3,7,14H,4,11H2/t7-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50386297
(CHEMBL2049098)Show InChI InChI=1S/C10H12N2O2/c1-6-3-2-4-9-7(6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs |
ACS Med Chem Lett 3: 187-192 (2012)
Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50126149
(CHEMBL3629573)Show SMILES O=C1NC(=O)\C(S1)=C\c1cccc(c1)-c1ccc2CCN3c2c1CCC3=O Show InChI InChI=1S/C21H16N2O3S/c24-18-7-6-16-15(5-4-13-8-9-23(18)19(13)16)14-3-1-2-12(10-14)11-17-20(25)22-21(26)27-17/h1-5,10-11H,6-9H2,(H,22,25,26)/b17-11- | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Colorado College
Curated by ChEMBL
| Assay Description Inhibition of rat KAT-2 |
J Med Chem 58: 8762-82 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00461 BindingDB Entry DOI: 10.7270/Q2C82C3F |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50126148
(CHEMBL3629572)Show SMILES CCS(=O)(=O)c1ccc(cc1)C(=O)C[C@H](N)C(O)=O |r| Show InChI InChI=1S/C12H15NO5S/c1-2-19(17,18)9-5-3-8(4-6-9)11(14)7-10(13)12(15)16/h3-6,10H,2,7,13H2,1H3,(H,15,16)/t10-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Colorado College
Curated by ChEMBL
| Assay Description Inhibition of rat KAT-2 |
J Med Chem 58: 8762-82 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00461 BindingDB Entry DOI: 10.7270/Q2C82C3F |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Rattus norvegicus) | BDBM50126148
(CHEMBL3629572)Show SMILES CCS(=O)(=O)c1ccc(cc1)C(=O)C[C@H](N)C(O)=O |r| Show InChI InChI=1S/C12H15NO5S/c1-2-19(17,18)9-5-3-8(4-6-9)11(14)7-10(13)12(15)16/h3-6,10H,2,7,13H2,1H3,(H,15,16)/t10-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TES Pharma S.r.l.
Curated by ChEMBL
| Assay Description Inhibition of rat liver KAT2 using [3H]-kynurenine incubated for 2 hrs by liquid scintillation spectrometry method |
J Med Chem 61: 745-759 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01254 BindingDB Entry DOI: 10.7270/Q22J6F80 |
More data for this Ligand-Target Pair | |