Compile Data Set for Download or QSAR

Found 14 hits of ic50 for UniProtKB: P02710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023331 ((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...) Show SMILES C1CC2NC1CCc1ccncc21 Show InChI InChI=1S/C11H14N2/c1-2-9-3-4-11(13-9)10-7-12-6-5-8(1)10/h5-7,9,11,13H,1-4H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone | 1...) Show SMILES CC(=O)C1=CCCC2CCC1N2 |t:3,THB:1:3:11:9.8| Show InChI InChI=1S/C10H15NO/c1-7(12)9-4-2-3-8-5-6-10(9)11-8/h4,8,10-11H,2-3,5-6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone | 1...) Show SMILES CC(=O)C1=CCCC2CCC1N2 |t:3,THB:1:3:11:9.8| Show InChI InChI=1S/C10H15NO/c1-7(12)9-4-2-3-8-5-6-10(9)11-8/h4,8,10-11H,2-3,5-6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023331 ((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...) Show SMILES C1CC2NC1CCc1ccncc21 Show InChI InChI=1S/C11H14N2/c1-2-9-3-4-11(13-9)10-7-12-6-5-8(1)10/h5-7,9,11,13H,1-4H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023328 (3-Pyrrolidin-2-yl-pyridine | CHEMBL1132 | Nornicot...) Show SMILES C1CNC(C1)c1cccnc1 Show InChI InChI=1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023327 (3-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca-...) Show SMILES Cc1nccc2CCC3CCC(N3)c12 Show InChI InChI=1S/C12H16N2/c1-8-12-9(6-7-13-8)2-3-10-4-5-11(12)14-10/h6-7,10-11,14H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023327 (3-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca-...) Show SMILES Cc1nccc2CCC3CCC(N3)c12 Show InChI InChI=1S/C12H16N2/c1-8-12-9(6-7-13-8)2-3-10-4-5-11(12)14-10/h6-7,10-11,14H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023328 (3-Pyrrolidin-2-yl-pyridine | CHEMBL1132 | Nornicot...) Show SMILES C1CNC(C1)c1cccnc1 Show InChI InChI=1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023329 (13-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca...) Show SMILES CN1C2CCC1c1cnccc1CC2 Show InChI InChI=1S/C12H16N2/c1-14-10-3-2-9-6-7-13-8-11(9)12(14)5-4-10/h6-8,10,12H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50023329 (13-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca...) Show SMILES CN1C2CCC1c1cnccc1CC2 Show InChI InChI=1S/C12H16N2/c1-14-10-3-2-9-6-7-13-8-11(9)12(14)5-4-10/h6-8,10,12H,2-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) BindingDB Entry DOI: 10.7270/Q2B27T8K
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50125936 (3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic a...) Show SMILES C[C@H](c1ccccc1)n1cncc1C(=O)OCCC1(C)N=N1 |c:22| Show InChI InChI=1S/C16H18N4O2/c1-12(13-6-4-3-5-7-13)20-11-17-10-14(20)15(21)22-9-8-16(2)18-19-16/h3-7,10-12H,8-9H2,1-2H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibition of currents when compound wascoapplied with acetylcholine to recombinant Torpedo nAcChoR (from 6 oocytes)				J Med Chem 46: 1257-65 (2003) Article DOI: 10.1021/jm020465v BindingDB Entry DOI: 10.7270/Q24J0FVZ
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Torpedo californica)	BDBM50125935 ((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...) Show SMILES CCOC(=O)c1cncn1[C@H](C)c1ccccc1 |r| Show InChI InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description In vitro inhibition of 5-[125I]-A-85,380 binding to alpha2 beta4 nicotinic acetylcholine receptor (nAChR) in rat brain				J Med Chem 46: 1257-65 (2003) Article DOI: 10.1021/jm020465v BindingDB Entry DOI: 10.7270/Q24J0FVZ
					More data for this Ligand-Target Pair				3D Structure (crystal)