Found 831 hits of ic50 data for polymerid = 50002941,50006230,6167 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Galectin-3
(Homo sapiens (Human)) | BDBM50581785
(CHEMBL5081052)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1nccs1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541746
(US11267811, Example A78)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Br)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541746
(US11267811, Example A78)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Br)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541671
(US11267811, Example 313)Show SMILES Cc1nnc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Br)c(F)c2)n1-c1cc(Cl)ccc1C(F)(F)F |r,wU:10.10,12.15,5.4,7.7,wD:13.14,(8.08,-1.9,;6.5,-2.1,;5.6,-3.34,;4.13,-2.87,;4.13,-1.33,;2.8,-.56,;2.8,.98,;1.46,1.75,;1.46,3.29,;.13,4.06,;.13,.98,;-1.2,1.75,;.13,-.56,;1.46,-1.33,;1.46,-2.87,;-1.2,-1.33,;-2.67,-.85,;-3.57,-2.1,;-2.67,-3.34,;-1.2,-2.87,;-5.06,-1.95,;-5.96,-3.2,;-7.49,-3.05,;-8.39,-4.3,;-8.13,-1.65,;-9.66,-1.5,;-7.23,-.4,;-7.87,1.01,;-5.7,-.55,;5.6,-.85,;5.99,.64,;4.9,1.73,;5.3,3.21,;4.21,4.3,;6.79,3.61,;7.88,2.52,;7.52,1,;8.61,-.09,;9.7,-1.18,;9.7,1,;7.52,-1.18,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541728
(US11267811, Example A58)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541639
(US11267811, Example 250)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM620313
(US20230295182, Example 1.45 | US20230295182, Examp...)Show SMILES COC1=C(N2C[C@@H](NN2)c2ccc(Cl)c(F)c2F)C(O)=C(CO)O[C@@H]1CC1=NO[C@@]2(C1)CC[C@@H](CC2)NC(=O)OC(C)(C)C |wU:29.31,6.9,24.27,wD:33.40,c:2,t:21,29,(-1.33,-.88,;-2.23,-2.13,;-3.76,-1.97,;-4.39,-.56,;-3.48,.69,;-1.94,.69,;-1.47,2.15,;-2.71,3.06,;-3.96,2.15,;-0,2.63,;1.14,1.6,;2.61,2.07,;2.93,3.58,;4.39,4.05,;1.78,4.61,;2.1,6.11,;.32,4.13,;-.83,5.16,;-5.92,-.4,;-6.55,1.01,;-6.83,-1.65,;-8.36,-1.48,;-9.26,-2.73,;-6.2,-3.05,;-4.67,-3.21,;-4.04,-4.62,;-2.51,-4.78,;-1.74,-6.11,;-.23,-5.79,;-.07,-4.26,;-1.48,-3.64,;-.07,-2.72,;1.26,-1.95,;2.59,-2.72,;2.59,-4.26,;1.26,-5.03,;3.93,-1.95,;5.26,-2.72,;5.26,-4.26,;6.6,-1.95,;7.93,-2.72,;9.26,-1.95,;9.26,-3.49,;7.93,-4.26,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581762
(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)Show SMILES OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| MCE
PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM541743
(US11267811, Example A73)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2F)n(n1)-c1cc(Cl)ccc1Br |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541674
(US11267811, Example 318)Show SMILES Cc1nnc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Br)c(F)c2)n1-c1cc(Cl)cc2cccnc12 |r,wU:10.10,12.15,5.4,7.7,wD:13.14,(7.43,-1.82,;5.94,-2.1,;5.04,-3.34,;3.57,-2.87,;3.57,-1.33,;2.24,-.56,;2.24,.98,;.91,1.75,;.91,3.29,;-.43,4.06,;-.43,.98,;-1.76,1.75,;-.43,-.56,;.91,-1.33,;.91,-2.87,;-1.76,-1.33,;-3.23,-.85,;-4.13,-2.1,;-3.23,-3.34,;-1.76,-2.87,;-5.62,-1.95,;-6.52,-3.2,;-8.05,-3.05,;-8.95,-4.3,;-8.68,-1.65,;-9.9,-1.5,;-7.79,-.4,;-8.42,1.01,;-6.26,-.55,;5.04,-.85,;5.44,.64,;4.35,1.73,;4.75,3.21,;3.66,4.3,;6.23,3.61,;7.32,2.52,;8.81,2.92,;9.9,1.83,;9.5,.35,;8.01,-.05,;6.92,1.04,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541742
(US11267811, Example A72)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2F)n(n1)-c1cc(Cl)ccc1Cl |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541728
(US11267811, Example A58)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2F)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541712
(US11267811, Example A42)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n(n1)-c1cc(Cl)ccc1C(C)(C)C |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541669
(US11267811, Example 311)Show SMILES Cc1nnc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n1-c1cc(Cl)ccc1C(F)(F)F |r,wU:10.10,12.15,5.4,7.7,wD:13.14,(7.99,-1.86,;6.5,-2.1,;5.6,-3.34,;4.13,-2.87,;4.13,-1.33,;2.8,-.56,;2.8,.98,;1.46,1.75,;1.46,3.29,;.13,4.06,;.13,.98,;-1.2,1.75,;.13,-.56,;1.46,-1.33,;1.46,-2.87,;-1.2,-1.33,;-2.67,-.85,;-3.57,-2.1,;-2.67,-3.34,;-1.2,-2.87,;-5.06,-1.95,;-5.96,-3.2,;-7.49,-3.05,;-8.39,-4.3,;-8.13,-1.65,;-9.66,-1.5,;-7.23,-.4,;-7.87,1.01,;-5.7,-.55,;5.6,-.85,;5.99,.64,;4.9,1.73,;5.3,3.21,;4.21,4.3,;6.79,3.61,;7.88,2.52,;7.52,1,;8.61,-.09,;9.7,-1.18,;9.7,1,;7.52,-1.18,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581778
(CHEMBL5090468)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cnc(OC)nc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM620309
(US20230295182, Example 1.41 | US20230295182, Examp...)Show SMILES COC1=C(N2C[C@@H](NN2)c2ccc(F)c(F)c2F)C(O)=C(CO)O[C@@H]1CC1=NO[C@@]2(C1)CC[C@@H](CC2)NC(=O)OC(C)(C)C |wU:29.31,6.9,24.27,wD:33.40,c:2,t:21,29,(-1.33,-.88,;-2.23,-2.13,;-3.76,-1.97,;-4.39,-.56,;-3.48,.69,;-1.94,.69,;-1.47,2.15,;-2.71,3.06,;-3.96,2.15,;-0,2.63,;1.14,1.6,;2.61,2.07,;2.93,3.58,;4.39,4.05,;1.78,4.61,;2.1,6.11,;.32,4.13,;-.83,5.16,;-5.92,-.4,;-6.55,1.01,;-6.83,-1.65,;-8.36,-1.48,;-9.26,-2.73,;-6.2,-3.05,;-4.67,-3.21,;-4.04,-4.62,;-2.51,-4.78,;-1.74,-6.11,;-.23,-5.79,;-.07,-4.26,;-1.48,-3.64,;-.07,-2.72,;1.26,-1.95,;2.59,-2.72,;2.59,-4.26,;1.26,-5.03,;3.93,-1.95,;5.26,-2.72,;5.26,-4.26,;6.6,-1.95,;7.93,-2.72,;9.26,-1.95,;9.26,-3.49,;7.93,-4.26,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632517
((2R,3R,4S,5R,6R)-4-(4-(4-chloro-2,3-difluorophenyl...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(F)c1F)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632544
((2R,3R,4S,5R,6R)-2-((3,5-dichlorophenyl)((1S,2S)-2...)Show SMILES CC(=O)O[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(C)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(Cl)c1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 12.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632510
((2R,3R,4S,5R,6R)-4-(4-(4-bromo-2,3-difluorophenyl)...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Br)c(F)c1F)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Br)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50549955
(CHEMBL4779606)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(Cl)c1F)C(=O)N(C)c1ccc2ncsc2c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human His6-tagged Galectin-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by HTRF assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00671
BindingDB Entry DOI: 10.7270/Q2QV3R57 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541675
(US11267811, Example 319)Show SMILES Cc1nnc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n1-c1cc(Cl)cc2cccnc12 |r,wU:10.10,12.15,5.4,7.7,wD:13.14,(7.49,-1.82,;6,-2.1,;5.1,-3.34,;3.63,-2.87,;3.63,-1.33,;2.3,-.56,;2.3,.98,;.97,1.75,;.97,3.29,;-.37,4.06,;-.37,.98,;-1.7,1.75,;-.37,-.56,;.97,-1.33,;.97,-2.87,;-1.7,-1.33,;-3.17,-.85,;-4.07,-2.1,;-3.17,-3.34,;-1.7,-2.87,;-5.56,-1.95,;-6.46,-3.2,;-7.99,-3.05,;-8.89,-4.3,;-8.62,-1.65,;-9.96,-1.5,;-7.73,-.4,;-8.36,1.01,;-6.2,-.55,;5.1,-.85,;5.5,.64,;4.41,1.73,;4.81,3.21,;3.72,4.3,;6.29,3.61,;7.38,2.52,;8.87,2.92,;9.96,1.83,;9.56,.35,;8.07,-.05,;6.98,1.04,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632552
((2R,3R,4S,5R,6R)-4-(4-(4-chloro-3,5-difluorophenyl...)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(Cl)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(Cl)c1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632505
((2R,3R,4S,5R,6R)-N-(3-bromo-5-cyanophenyl)-4-(4-(2...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Br)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50549956
(CHEMBL4759243)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Br)c(F)c1F)C(=O)N(C)c1ccc2ncsc2c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human His6-tagged Galectin-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by HTRF assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00671
BindingDB Entry DOI: 10.7270/Q2QV3R57 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541740
(US11267811, Example A70)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c3ccccc3c2)n(n1)-c1ccc2ncsc2c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541639
(US11267811, Example 250)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2ccc(Cl)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM620311
(US20230295182, Example 1.43 | US20230295182, Examp...)Show SMILES COC1=C(N2C[C@@H](NN2)c2ccc(C)c(F)c2F)C(O)=C(CO)O[C@@H]1CC1=NO[C@@]2(C1)CC[C@@H](CC2)NC(=O)OC(C)(C)C |wU:29.31,6.9,24.27,wD:33.40,c:2,t:21,29,(-1.33,-.88,;-2.23,-2.13,;-3.76,-1.97,;-4.39,-.56,;-3.48,.69,;-1.94,.69,;-1.47,2.15,;-2.71,3.06,;-3.96,2.15,;-0,2.63,;1.14,1.6,;2.61,2.07,;2.93,3.58,;4.39,4.05,;1.78,4.61,;2.1,6.11,;.32,4.13,;-.83,5.16,;-5.92,-.4,;-6.55,1.01,;-6.83,-1.65,;-8.36,-1.48,;-9.26,-2.73,;-6.2,-3.05,;-4.67,-3.21,;-4.04,-4.62,;-2.51,-4.78,;-1.74,-6.11,;-.23,-5.79,;-.07,-4.26,;-1.48,-3.64,;-.07,-2.72,;1.26,-1.95,;2.59,-2.72,;2.59,-4.26,;1.26,-5.03,;3.93,-1.95,;5.26,-2.72,;5.26,-4.26,;6.6,-1.95,;7.93,-2.72,;9.26,-1.95,;9.26,-3.49,;7.93,-4.26,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632502
((2R,3R,4S,5R,6R)-N-(3,5-dichlorophenyl)-4-(4-(2,3-...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(Cl)c1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 15.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632547
((2R,3R,4S,5R,6R)-4-(4-(4-chloro-3,5-difluorophenyl...)Show SMILES CC(=O)O[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(Cl)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632478
((2R,3R,4S,5R,6R)-N-(3-bromo-5-cyanophenyl)-4-(4-(3...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(C)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Br)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541681
(US11267811, Example A11)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n(n1)-c1cc(Cl)cc2cccnc12 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541700
(US11267811, Example A30)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n(n1)-c1cc2sc(C)nc2cc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581782
(CHEMBL5093414)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cccc(n1)C(=O)OC)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM620359
(US20230295182, Example 2.09 | ethyl ((5r,8R)-3-(((...)Show SMILES CCOC(=O)N[C@H]1CC[C@@]2(CC(C[C@H]3O[C@H](CO)[C@H](O)[C@@H]([C@H]3OC)n3cc(nn3)-c3ccc(C)c(F)c3F)=NO2)CC1 |wU:9.42,21.22,13.12,wD:15.15,18.18,20.24,6.5,c:40,(9.26,-1.95,;7.93,-2.72,;6.6,-1.95,;5.26,-2.72,;5.26,-4.26,;3.93,-1.95,;2.59,-2.72,;1.26,-1.95,;-.07,-2.72,;-.07,-4.26,;-1.48,-3.64,;-2.51,-4.78,;-4.04,-4.62,;-4.67,-3.21,;-6.2,-3.05,;-6.83,-1.65,;-8.36,-1.48,;-9.26,-2.73,;-5.92,-.4,;-6.55,1.01,;-4.39,-.56,;-3.76,-1.97,;-2.23,-2.13,;-1.33,-.88,;-3.48,.69,;-1.94,.69,;-1.47,2.15,;-2.71,3.06,;-3.96,2.15,;-0,2.63,;1.14,1.6,;2.61,2.07,;2.93,3.58,;4.39,4.05,;1.78,4.61,;2.1,6.11,;.32,4.13,;-.83,5.16,;-1.74,-6.11,;-.23,-5.79,;1.26,-5.03,;2.59,-4.26,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632513
((2R,3R,4S,5R,6R)-N-(3-bromo-5-cyanophenyl)-4-(4-(3...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Br)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632606
((2R,3R,4S,5R,6R)-N-(3-bromo-5-cyanophenyl)-4-(4-(2...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(C)c(F)c1F)C(=O)N([C@H]1CC[C@@H]1O)c1cc(Br)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632476
((2R,3R,4S,5R,6R)-N-(3-chloro-5-cyanophenyl)-4-(4-(...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(C)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632519
((2R,3R,4S,5R,6R)-N-(3-bromo-5-cyanophenyl)-4-(4-(4...)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(F)c1F)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Br)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581775
(CHEMBL5087430)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cnccn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50549957
(CHEMBL4791572)Show SMILES CO[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(Cl)c(F)c1Cl)C(=O)N(C)c1ccc2ncsc2c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of recombinant human His6-tagged Galectin-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by HTRF assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00671
BindingDB Entry DOI: 10.7270/Q2QV3R57 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581772
(CHEMBL5076024)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ccccn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50581774
(CHEMBL5091613)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cncnc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM50581779
(CHEMBL5092373)Show SMILES [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1ncc(F)cn1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c02001
BindingDB Entry DOI: 10.7270/Q23X8BJ6 |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM50594519
(CHEMBL5206873)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(Cl)c(F)c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| PDB
Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00517
BindingDB Entry DOI: 10.7270/Q2DR30HS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Galectin-3
(Homo sapiens (Human)) | BDBM620361
(US20230295182, Example 2.11 | ethyl ((5r,8R)-3-(((...)Show SMILES CCOC(=O)N[C@H]1CC[C@@]2(CC(C[C@H]3O[C@H](CO)[C@H](O)[C@@H]([C@H]3OC)n3cc(nn3)-c3ccc(Cl)c(F)c3F)=NO2)CC1 |wU:9.42,21.22,13.12,wD:15.15,18.18,20.24,6.5,c:40,(9.26,-1.95,;7.93,-2.72,;6.6,-1.95,;5.26,-2.72,;5.26,-4.26,;3.93,-1.95,;2.59,-2.72,;1.26,-1.95,;-.07,-2.72,;-.07,-4.26,;-1.48,-3.64,;-2.51,-4.78,;-4.04,-4.62,;-4.67,-3.21,;-6.2,-3.05,;-6.83,-1.65,;-8.36,-1.48,;-9.26,-2.73,;-5.92,-.4,;-6.55,1.01,;-4.39,-.56,;-3.76,-1.97,;-2.23,-2.13,;-1.33,-.88,;-3.48,.69,;-1.94,.69,;-1.47,2.15,;-2.71,3.06,;-3.96,2.15,;-0,2.63,;1.14,1.6,;2.61,2.07,;2.93,3.58,;4.39,4.05,;1.78,4.61,;2.1,6.11,;.32,4.13,;-.83,5.16,;-1.74,-6.11,;-.23,-5.79,;1.26,-5.03,;2.59,-4.26,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632551
((2R,3R,4S,5R,6R)-N-(3-chloro-5-cyanophenyl)-4-(4-(...)Show SMILES Cc1c(F)cc(cc1F)-c1cn(nn1)[C@H]1[C@@H](O)[C@@H](CO)O[C@H]([C@@H]1O)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 19.3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632546
((2R,3R,4S,5R,6R)-4-(4-(4-chloro-3,5-difluorophenyl...)Show SMILES CC(=O)O[C@H]1[C@@H](O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1cc(F)c(Cl)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(Cl)c1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 19.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM632553
((2R,3R,4S,5R,6R)-4-(4-(4-chloro-3,5-difluorophenyl...)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(Cl)c(F)c1)C(=O)N([C@H]1CCC[C@@H]1O)c1cc(Cl)cc(c1)C#N | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541474
(US11267811, Example 68)Show SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c(F)c(F)c2)n(n1)-c1cc(Cl)ccc1Br |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
Galectin-3
(Homo sapiens (Human)) | BDBM541478
(US11267811, Example 72)Show SMILES CCc1ccc(Cl)cc1-n1nc(C)nc1[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D221TZ |
More data for this
Ligand-Target Pair | |
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