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Compile Data Set for Download or QSAR

Found 67 hits of ic50 data for polymerid = 50003017   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50065258
PNG
((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
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n/an/a 5n/an/an/an/an/an/a



Université de Haute-Alsace

Curated by ChEMBL


Assay Description
Inhibition of bovine alpha-L-fucosidase


Bioorg Med Chem Lett 16: 1172-4 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.100
BindingDB Entry DOI: 10.7270/Q2Q81CNB
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442341
PNG
(CHEMBL2442786)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccccc2F)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H19FN2O4/c1-7-12(19)14(21)13(20)10(16-7)6-11(18)17-9-5-3-2-4-8(9)15/h2-5,7,10,12-14,16,19-21H,6H2,1H3,(H,17,18)/t7-,10+,12+,13+,14+/m0/s1
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n/an/a 12n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442343
PNG
(CHEMBL2442784)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccc(C)cc2C)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C16H24N2O4/c1-8-4-5-11(9(2)6-8)18-13(19)7-12-15(21)16(22)14(20)10(3)17-12/h4-6,10,12,14-17,20-22H,7H2,1-3H3,(H,18,19)/t10-,12+,14+,15+,16+/m0/s1
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n/an/a 21n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442344
PNG
(CHEMBL2442783)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccc(C)cc2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H22N2O4/c1-8-3-5-10(6-4-8)17-12(18)7-11-14(20)15(21)13(19)9(2)16-11/h3-6,9,11,13-16,19-21H,7H2,1-2H3,(H,17,18)/t9-,11+,13+,14+,15+/m0/s1
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n/an/a 26n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442340
PNG
(CHEMBL2442787)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2cccc(F)c2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H19FN2O4/c1-7-12(19)14(21)13(20)10(16-7)6-11(18)17-9-4-2-3-8(15)5-9/h2-5,7,10,12-14,16,19-21H,6H2,1H3,(H,17,18)/t7-,10+,12+,13+,14+/m0/s1
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n/an/a 28n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442339
PNG
(CHEMBL2442788)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccc(F)cc2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H19FN2O4/c1-7-12(19)14(21)13(20)10(16-7)6-11(18)17-9-4-2-8(15)3-5-9/h2-5,7,10,12-14,16,19-21H,6H2,1H3,(H,17,18)/t7-,10+,12+,13+,14+/m0/s1
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n/an/a 30n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442345
PNG
(CHEMBL2442782)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2cccc(C)c2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H22N2O4/c1-8-4-3-5-10(6-8)17-12(18)7-11-14(20)15(21)13(19)9(2)16-11/h3-6,9,11,13-16,19-21H,7H2,1-2H3,(H,17,18)/t9-,11+,13+,14+,15+/m0/s1
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n/an/a 40n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442338
PNG
(CHEMBL2442773)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccc(F)cc2F)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H18F2N2O4/c1-6-12(20)14(22)13(21)10(17-6)5-11(19)18-9-3-2-7(15)4-8(9)16/h2-4,6,10,12-14,17,20-22H,5H2,1H3,(H,18,19)/t6-,10+,12+,13+,14+/m0/s1
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n/an/a 42n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442348
PNG
(CHEMBL2442779)
Show SMILES COc1ccc(NC(=O)C[C@H]2N[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)cc1 |r|
Show InChI InChI=1S/C15H22N2O5/c1-8-13(19)15(21)14(20)11(16-8)7-12(18)17-9-3-5-10(22-2)6-4-9/h3-6,8,11,13-16,19-21H,7H2,1-2H3,(H,17,18)/t8-,11+,13+,14+,15+/m0/s1
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n/an/a 43n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442346
PNG
(CHEMBL2442781)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccccc2C)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H22N2O4/c1-8-5-3-4-6-10(8)17-12(18)7-11-14(20)15(21)13(19)9(2)16-11/h3-6,9,11,13-16,19-21H,7H2,1-2H3,(H,17,18)/t9-,11+,13+,14+,15+/m0/s1
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n/an/a 47n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442350
PNG
(CHEMBL2442777)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2ccccc2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H20N2O4/c1-8-12(18)14(20)13(19)10(15-8)7-11(17)16-9-5-3-2-4-6-9/h2-6,8,10,12-15,18-20H,7H2,1H3,(H,16,17)/t8-,10+,12+,13+,14+/m0/s1
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n/an/a 47n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50065258
PNG
((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442347
PNG
(CHEMBL2442780)
Show SMILES CCCCNC(=O)C[C@H]1N[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H24N2O4/c1-3-4-5-13-9(15)6-8-11(17)12(18)10(16)7(2)14-8/h7-8,10-12,14,16-18H,3-6H2,1-2H3,(H,13,15)/t7-,8+,10+,11+,12+/m0/s1
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n/an/a 160n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442349
PNG
(CHEMBL2442778)
Show SMILES C[C@@H]1N[C@H](CC(=O)NCc2ccccc2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H22N2O4/c1-9-13(19)15(21)14(20)11(17-9)7-12(18)16-8-10-5-3-2-4-6-10/h2-6,9,11,13-15,17,19-21H,7-8H2,1H3,(H,16,18)/t9-,11+,13+,14+,15+/m0/s1
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n/an/a 170n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442351
PNG
(CHEMBL2442776)
Show SMILES C[C@@H]1N[C@H](CCCc2ccccc2)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H23NO3/c1-10-13(17)15(19)14(18)12(16-10)9-5-8-11-6-3-2-4-7-11/h2-4,6-7,10,12-19H,5,8-9H2,1H3/t10-,12+,13+,14+,15+/m0/s1
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n/an/a 190n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442342
PNG
(CHEMBL2442785)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2c(C)cc(C)cc2C)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C17H26N2O4/c1-8-5-9(2)14(10(3)6-8)19-13(20)7-12-16(22)17(23)15(21)11(4)18-12/h5-6,11-12,15-18,21-23H,7H2,1-4H3,(H,19,20)/t11-,12+,15+,16+,17+/m0/s1
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n/an/a 220n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442337
PNG
(CHEMBL2442774)
Show SMILES C[C@@H]1N[C@H](CC(=O)Nc2c(F)cc(F)cc2F)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H17F3N2O4/c1-5-12(21)14(23)13(22)9(18-5)4-10(20)19-11-7(16)2-6(15)3-8(11)17/h2-3,5,9,12-14,18,21-23H,4H2,1H3,(H,19,20)/t5-,9+,12+,13+,14+/m0/s1
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n/an/a 230n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50163439
PNG
((2S,3R,4S,5R)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Show SMILES OC[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m0/s1
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n/an/a 630n/an/an/an/an/an/a



Toyama Medical and Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibitory concentration against bovine alpha-L-fucosidase


J Med Chem 48: 2036-44 (2005)


Article DOI: 10.1021/jm0495881
BindingDB Entry DOI: 10.7270/Q2DF6S0M
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50242268
PNG
(2,5-Imino-1,2,5-trideoxy-L-glucitol | CHEMBL502230)
Show SMILES C[C@H]1N[C@@H](CO)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(2-8)7-3/h3-10H,2H2,1H3/t3-,4+,5+,6+/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometrically


J Nat Prod 65: 198-202 (2002)


BindingDB Entry DOI: 10.7270/Q2ZW1KN6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50442352
PNG
(CHEMBL2442775)
Show SMILES CCCCCC[C@H]1N[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H25NO3/c1-3-4-5-6-7-9-11(15)12(16)10(14)8(2)13-9/h8-16H,3-7H2,1-2H3/t8-,9+,10+,11+,12+/m0/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)


Article DOI: 10.1016/j.bmc.2013.08.028
BindingDB Entry DOI: 10.7270/Q2G73G5J
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50321922
PNG
((3S,4S,5R,6S)-3-(p-Phenylbenzoylaminomethyl)-6-met...)
Show SMILES C[C@@H]1NN[C@@H](CNC(=O)c2ccc(cc2)-c2ccccc2)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C19H23N3O3/c1-12-17(23)18(24)16(22-21-12)11-20-19(25)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-10,12,16-18,21-24H,11H2,1H3,(H,20,25)/t12-,16-,17+,18-/m0/s1
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n/an/a 8.60E+3n/an/an/an/an/an/a



University of Seville

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha L-fucosidase


Bioorg Med Chem 18: 4648-60 (2011)


Article DOI: 10.1016/j.bmc.2010.05.026
BindingDB Entry DOI: 10.7270/Q2G161TR
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551003
PNG
(CHEMBL4748590)
Show SMILES Cc1cc2\C(OC(=O)c2c(=O)[nH]1)=C\c1ccc(CO)n1CCc1c[nH]c2ccccc12
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n/an/a 1.29E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50278882
PNG
((2S,3S,4S,5S,6R)-2-((2R,3S,4S,5R,6R)-3,5-dihydroxy...)
Show SMILES OCC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H]1O |r|
Show InChI InChI=1S/C19H35NO14/c21-2-1-6-16(10(25)7(3-22)20-6)33-19-15(30)17(12(27)9(5-24)32-19)34-18-14(29)13(28)11(26)8(4-23)31-18/h6-30H,1-5H2/t6-,7-,8-,9-,10-,11-,12-,13+,14+,15+,16-,17+,18+,19+/m1/s1
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n/an/a 1.30E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release after 30 mins by spectrophotometry


J Nat Prod 65: 1875-81 (2002)


Article DOI: 10.1021/np020296h
BindingDB Entry DOI: 10.7270/Q2NC60Z4
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551001
PNG
(CHEMBL4745549)
Show SMILES OCc1ccc2CO[C@@H](Cn12)c1ccc(O)cc1 |r|
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n/an/a 2.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551005
PNG
(CHEMBL4757703)
Show SMILES Cc1cc2\C(OC(=O)c2c(=O)[nH]1)=C\c1ccc(CO)n1-c1ccc(O)cc1
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n/an/a 2.17E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50278884
PNG
((1R*,2R*,3R*,5R*,7S*,7a*R)-3-hydroxymethyl-5-methy...)
Show SMILES C[C@@H]1C[C@H](O)[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)N12 |r|
Show InChI InChI=1S/C9H17NO4/c1-4-2-6(12)7-9(14)8(13)5(3-11)10(4)7/h4-9,11-14H,2-3H2,1H3/t4-,5-,6+,7-,8-,9-/m1/s1
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n/an/a 2.30E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release after 30 mins by spectrophotometry


J Nat Prod 65: 1875-81 (2002)


Article DOI: 10.1021/np020296h
BindingDB Entry DOI: 10.7270/Q2NC60Z4
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50321921
PNG
((3S,4S,5R,6S)-3-Hydroxymethyl-6-methylhexahydropyr...)
Show SMILES C[C@@H]1NN[C@@H](CO)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H14N2O3/c1-3-5(10)6(11)4(2-9)8-7-3/h3-11H,2H2,1H3/t3-,4-,5+,6-/m0/s1
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n/an/a 3.00E+4n/an/an/an/an/an/a



University of Seville

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha L-fucosidase


Bioorg Med Chem 18: 4648-60 (2011)


Article DOI: 10.1016/j.bmc.2010.05.026
BindingDB Entry DOI: 10.7270/Q2G161TR
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551006
PNG
(CHEMBL4800248)
Show SMILES CCOC(=O)c1ccc(cc1)-n1c(CO)ccc1\C=C1/OC(=O)c2c1cc(C)[nH]c2=O
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n/an/a 3.04E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM11318
PNG
(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)
Show SMILES Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1
Show InChI InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
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n/an/a 3.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50005886
PNG
(1,8-Dihydroxy-3-methoxy-6-methylanthraquinone | 1,...)
Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1
Show InChI InChI=1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3
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n/an/a 3.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50085551
PNG
(1,8-Dihydroxy-3-hydroxymethyl-anthraquinone | 1,8-...)
Show SMILES OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
Show InChI InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2
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n/an/a 3.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM32021
PNG
(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)
Show SMILES OC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
Show InChI InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
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TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50242269
PNG
(2,5-dideoxy-2,5-imino-D-fucitol | CHEMBL458368)
Show SMILES C[C@H]1N[C@@H](CO)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(2-8)7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m1/s1
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n/an/a 3.50E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release by spectrophotometrically


J Nat Prod 65: 198-202 (2002)


BindingDB Entry DOI: 10.7270/Q2ZW1KN6
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551004
PNG
(CHEMBL4758678)
Show SMILES Cc1cc2\C(OC(=O)c2c(=O)[nH]1)=C\c1ccc(CO)n1-c1ccccc1
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n/an/a 3.84E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50065259
PNG
((2R,3R,4R,5R)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
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n/an/a 3.90E+4n/an/an/an/an/an/a



Toyama Medical and Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibitory concentration against alpha-L-fucosidase of bovine epididymis


J Med Chem 48: 2036-44 (2005)


Article DOI: 10.1021/jm0495881
BindingDB Entry DOI: 10.7270/Q2DF6S0M
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50550996
PNG
(CHEMBL4783560)
Show SMILES OC[C@@H]1N[C@H]([C@H](O)[C@H]1O)c1ccc(O)cc1 |r|
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n/an/a 4.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50550995
PNG
(L-RADICAMINE A)
Show SMILES COc1ccc(cc1O)[C@@H]1N[C@@H](CO)[C@H](O)[C@H]1O |r|
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n/an/a 4.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50259958
PNG
((2R,3S,4S,5S)-2-(2-hydroxyethyl)-5-(hydroxymethyl)...)
Show SMILES OCC[C@H]1N[C@@H](CO)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C7H15NO4/c9-2-1-4-6(11)7(12)5(3-10)8-4/h4-12H,1-3H2/t4-,5+,6+,7+/m1/s1
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n/an/a 5.00E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of bovine epididymis alpha-L-fucosidase at 1000 uM


J Nat Prod 61: 625-8 (1998)


Article DOI: 10.1021/np9705726
BindingDB Entry DOI: 10.7270/Q2F47NXN
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551002
PNG
(CHEMBL4750240)
Show SMILES Cc1cc2\C(OC(=O)c2c(=O)[nH]1)=C\c1ccc(CO)n1Cc1ccccc1
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n/an/a 5.11E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM19459
PNG
(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Show SMILES Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O
Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
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n/an/a 5.40E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM24783
PNG
(4H-chromen-4-one | chromone, 12)
Show SMILES O=c1ccoc2ccccc12
Show InChI InChI=1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H
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TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50360268
PNG
(CHEMBL1933098)
Show SMILES C[C@@H]1CNC[C@@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C7H15NO3/c1-4-2-8-3-5(9)7(11)6(4)10/h4-11H,2-3H2,1H3/t4-,5-,6-,7-/m1/s1
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n/an/a 6.40E+4n/an/an/an/an/an/a



UMR CNRS 7201

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 20: 641-9 (2012)


Article DOI: 10.1016/j.bmc.2010.09.053
BindingDB Entry DOI: 10.7270/Q2GB24HJ
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50550999
PNG
(CHEMBL4796653)
Show SMILES [O-][N+](=O)c1ccccc1\C=C1/C(=O)Nc2cc(Cl)ccc12
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n/an/a 6.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50551000
PNG
(CHEMBL4751456)
Show SMILES CC(C)c1ccc(\C=C2/C(=O)Nc3cc(Cl)ccc23)cc1
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n/an/a 6.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50550998
PNG
(CHEMBL4788384)
Show SMILES Oc1ccc(\C=C2/C(=O)Nc3cc(Cl)ccc23)cc1O
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n/an/a 6.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50550997
PNG
(CHEMBL4745678)
Show SMILES CC[C@H](O)[C@@H](O)[C@@H](O)[C@H](OS([O-])(=O)=O)[C@H](O)C[S@@+]1C[C@@H](O)[C@H](O)[C@H]1CO |r|
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PC cid
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UniChem
Article
PubMed
n/an/a 7.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50437448
PNG
(CHEMBL2409344)
Show SMILES CC[C@@H]1N[C@@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(3-10)9-4/h4-13H,2-3H2,1H3/t4-,5-,6-,7+,8+/m0/s1
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UniChem

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Article
PubMed
n/an/a 7.20E+4n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 21: 4803-12 (2013)


Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50279408
PNG
((2R,3S,4S,5S,6R)-2-((2R,3R,4R,5R)-4-hydroxy-2-(2-h...)
Show SMILES OCC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C13H25NO9/c15-2-1-5-12(8(18)6(3-16)14-5)23-13-11(21)10(20)9(19)7(4-17)22-13/h5-21H,1-4H2/t5-,6-,7-,8-,9-,10+,11+,12-,13+/m1/s1
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n/an/a 7.80E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release after 30 mins by spectrophotometry


J Nat Prod 65: 1875-81 (2002)


Article DOI: 10.1021/np020296h
BindingDB Entry DOI: 10.7270/Q2NC60Z4
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM50341204
PNG
((Z)-3-butylidenephthalide | CHEMBL1765390)
Show SMILES CCC\C=C1\OC(=O)c2ccccc12
Show InChI InChI=1S/C12H12O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h4-8H,2-3H2,1H3/b11-8+
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PubMed
n/an/a 8.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
Tissue alpha-L-fucosidase


(Bos taurus)
BDBM92460
PNG
(Casuarine)
Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H]2[C@H](O)[C@@H](O)CN12
Show InChI InChI=1S/C8H15NO5/c10-2-3-6(12)8(14)5-7(13)4(11)1-9(3)5/h3-8,10-14H,1-2H2/t3-,4+,5-,6-,7-,8-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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MMDB
PC cid
PC sid
PDB
UniChem

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Article
PubMed
n/an/a 8.20E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112034
BindingDB Entry DOI: 10.7270/Q2KW5KN9
More data for this
Ligand-Target Pair
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