Compile Data Set for Download or QSAR

Found 17 hits of ic50 data for polymerid = 50003122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23979 ((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCc1ccccc1 Show InChI InChI=1S/C20H24N2O/c21-19-14-17-11-4-5-12-18(17)15-20(19)22-23-13-7-6-10-16-8-2-1-3-9-16/h1-5,8-9,11-12,19H,6-7,10,13-15,21H2/b22-20-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23973 (3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...) Show SMILES NC1Cc2ccccc2CC1=O Show InChI InChI=1S/C10H11NO/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-4,9H,5-6,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23980 ((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O/c22-20-15-18-12-6-7-13-19(18)16-21(20)23-24-14-8-2-5-11-17-9-3-1-4-10-17/h1,3-4,6-7,9-10,12-13,20H,2,5,8,11,14-16,22H2/b23-21-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23984 (3-amino-1,2,3,4-tetrahydronaphthalene-2-phosphonic...) Show SMILES OP(O)(O)C1Cc2ccccc2CC1=N Show InChI InChI=1S/C10H14NO3P/c11-9-5-7-3-1-2-4-8(7)6-10(9)15(12,13)14/h1-4,10-15H,5-6H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23977 ((3Z)-3-[(2-phenylethoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCc1ccccc1 Show InChI InChI=1S/C18H20N2O/c19-17-12-15-8-4-5-9-16(15)13-18(17)20-21-11-10-14-6-2-1-3-7-14/h1-9,17H,10-13,19H2/b20-18-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23976 ((3Z)-3-[(benzyloxy)imino]-1,2,3,4-tetrahydronaphth...) Show SMILES NC1Cc2ccccc2C\C1=N\OCc1ccccc1 Show InChI InChI=1S/C17H18N2O/c18-16-10-14-8-4-5-9-15(14)11-17(16)19-20-12-13-6-2-1-3-7-13/h1-9,16H,10-12,18H2/b19-17-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23978 ((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCc1ccccc1 Show InChI InChI=1S/C19H22N2O/c20-18-13-16-10-4-5-11-17(16)14-19(18)21-22-12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18H,6,9,12-14,20H2/b21-19-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23982 (1-(3-amino-1,2,3,4-tetrahydronaphthalen-2-yl)ethan...) Show SMILES CC(=O)C1Cc2ccccc2CC1N Show InChI InChI=1S/C12H15NO/c1-8(14)11-6-9-4-2-3-5-10(9)7-12(11)13/h2-5,11-12H,6-7,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23988 (2-amino-1,2,3,4-tetrahydroisoquinolin-3-one | N-Su...) Show SMILES NN1Cc2ccccc2CC1=O Show InChI InChI=1S/C9H10N2O/c10-11-6-8-4-2-1-3-7(8)5-9(11)12/h1-4H,5-6,10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23975 ((3Z)-3-(methoxyimino)-1,2,3,4-tetrahydronaphthalen...) Show SMILES CO\N=C1\Cc2ccccc2CC1N Show InChI InChI=1S/C11H14N2O/c1-14-13-11-7-9-5-3-2-4-8(9)6-10(11)12/h2-5,10H,6-7,12H2,1H3/b13-11-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM50336495 (7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...) Show SMILES NC1CCc2ccccc2CC1=O Show InChI InChI=1S/C11H13NO/c12-10-6-5-8-3-1-2-4-9(8)7-11(10)13/h1-4,10H,5-7,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Haute Alsace Curated by ChEMBL					Assay Description Inhibition of Aeromonas proteolytica leucyl aminopeptidase using L-leucine para-notroanilide as substrate assessed as release of para-nitroaniline by...				Bioorg Med Chem 21: 6447-55 (2013) Article DOI: 10.1016/j.bmc.2013.08.044 BindingDB Entry DOI: 10.7270/Q2PR7XF2
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23981 ((2S)-1,2,3,4-Tetrahydro-naphthalen-2-ylamine | 1,2...) Show SMILES NC1CCc2ccccc2C1 Show InChI InChI=1S/C10H13N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4,10H,5-7,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23974 ((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...) Show SMILES ONC1Cc2ccccc2CC1=N Show InChI InChI=1S/C10H12N2O/c11-9-5-7-3-1-2-4-8(7)6-10(9)12-13/h1-4,10-13H,5-6H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23985 (3,4-dihydro-1H-2-benzopyran-3-one | isochromanone,...) Show SMILES O=C1Cc2ccccc2CO1 Show InChI InChI=1S/C9H8O2/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-4H,5-6H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM23989 (1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...) Show SMILES O=C1CCc2ccccc2C1 Show InChI InChI=1S/C10H10O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4H,5-7H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM50442432 (CHEMBL2443108) Show SMILES N[C@H]1[C@@H](O)Cc2ccccc2CC1=O |r| Show InChI InChI=1S/C11H13NO2/c12-11-9(13)5-7-3-1-2-4-8(7)6-10(11)14/h1-4,9,11,13H,5-6,12H2/t9-,11-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Haute Alsace Curated by ChEMBL					Assay Description Inhibition of Aeromonas proteolytica leucyl aminopeptidase using L-leucine para-notroanilide as substrate assessed as release of para-nitroaniline by...				Bioorg Med Chem 21: 6447-55 (2013) Article DOI: 10.1016/j.bmc.2013.08.044 BindingDB Entry DOI: 10.7270/Q2PR7XF2
					More data for this Ligand-Target Pair