Compile Data Set for Download or QSAR

Found 356 hits of ic50 for UniProtKB: Q9UJM8   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581194 (5-(4-(2-(3-chlorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1cccc(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581193 (5-(4-(2-(4-chlorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM50572931 (CHEMBL4855986) Show SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)-c2cccc(Oc3[nH]nnc3C(O)=O)c2)-c2nc(cs2)C(O)=O)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00196 BindingDB Entry DOI: 10.7270/Q2V128MV
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581140 (5-(4-(()ethynyl)phenoxy)-1H- 1,2,3-triazole-4-car...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1ccc2[nH]ncc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581172 (5-(4-((3- cyanophenyl)ethynyl)-3- fluorophenoxy)...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(C#Cc2cccc(c2)C#N)c(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581191 (5-(4-(2-(4-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581192 (5-(3-(2-(4-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581198 (5-(3-(2-(6-methylpyridin-3- yl)ethynyl)phenoxy)-1...) Show SMILES Cc1ccc(cn1)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581199 (5-(3-(2-(2-methylpyridin-4- yl)ethynyl)phenoxy)-1...) Show SMILES Cc1cc(ccn1)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581211 (5-(3-(2-(1H-indazol-5- yl)ethynyl)phenoxy)-1H-1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1ccc2[nH]ncc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581232 (5-(3-(2-(1H-indazol-4- yl)ethynyl)phenoxy)-1H-1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1cccc2[nH]ncc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581234 (5-(3-(2-(1H-indazol-6- yl)ethynyl)phenoxy)-1H-1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1ccc2cn[nH]c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581180 (5-(4-(2-(3-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581143 (5-(3-fluoro-4- (phenylethynyl)phenoxy)-1H- 1,2,3...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(C#Cc2ccccc2)c(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581148 (5-(3-((3- chlorophenyl)ethynyl)phenoxy)- 1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1cccc(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581155 (5-(3-(2-(1-methyl-1H-pyrazol- 4-yl)ethynyl)phenox...) Show SMILES Cn1cc(cn1)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581159 (5-(3-((1-methyl-2-oxo-1,2- dihydropyridin-4- yl)...) Show SMILES Cn1ccc(cc1=O)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581161 (5-(4-fluoro-3-(2- phenylethynyl)phenoxy)-1H- 1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(F)c(c1)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581164 (5-(4-methyl-3-(2- phenylethynyl)phenoxy)-1H- 1,2...) Show SMILES Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581170 (5-(3-((4- cyanophenyl)ethynyl)-4- fluorophenoxy)...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(F)c(c1)C#Cc1ccc(cc1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581171 (5-(4-((4- cyanophenyl)ethynyl)-3- fluorophenoxy)...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(C#Cc2ccc(cc2)C#N)c(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM50572933 (CHEMBL4861379) Show SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)-c2ccc(Sc3nn[nH]c3C(O)=O)cc2)-c2nc(cs2)C(O)=O)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00196 BindingDB Entry DOI: 10.7270/Q2V128MV
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM50572932 (CHEMBL4850573) Show SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)-c2ccc(Oc3nn[nH]c3C(O)=O)cc2)-c2nc(cs2)C(O)=O)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00196 BindingDB Entry DOI: 10.7270/Q2V128MV
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM560934 (5-(3- (benzo[d][1,3]dioxol- 5-yl)phenoxy)-1H- 1,2,...) Show SMILES C1Oc2ccc(cc2O1)-c1cccc(Oc2cnn[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy...				Citation and Details BindingDB Entry DOI: 10.7270/Q2D221VD
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581183 (5-(4-(2-(3- methoxyphenyl)ethynyl)phenoxy)- 1H-1...) Show SMILES COc1cccc(c1)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581219 (5-(3-(2-(1-methyl-1H-indazol- 4-yl)ethynyl)phenox...) Show SMILES Cn1ncc2c(cccc12)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581220 (5-(4-(2-(1-methyl-1H-indazol- 5-yl)ethynyl)phenox...) Show SMILES Cn1ncc2cc(ccc12)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581221 (5-(3-(2-(1-methyl-1H-indazol- 5-yl)ethynyl)phenox...) Show SMILES Cn1ncc2cc(ccc12)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581222 (5-(4-(2-(1-methyl-1H-indazol- 6-yl)ethynyl)phenox...) Show SMILES Cn1ncc2ccc(cc12)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581223 (5-(3-(2-(1-methyl-1H-indazol- 6-yl)ethynyl)phenox...) Show SMILES Cn1ncc2ccc(cc12)C#Cc1cccc(Oc2[nH]nnc2C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581229 (5-(4-(2-(1-methyl-1H-indazol- 7-yl)ethynyl)phenox...) Show SMILES Cn1ncc2cccc(C#Cc3ccc(Oc4[nH]nnc4C(O)=O)cc3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581230 (5-(3-(2-(1-methyl-1H-indazol- 7-yl)ethynyl)phenox...) Show SMILES Cn1ncc2cccc(C#Cc3cccc(Oc4[nH]nnc4C(O)=O)c3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581231 (5-(4-(2-(1H-indazol-4- yl)ethynyl)phenoxy)-1H-1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1cccc2[nH]ncc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581233 (5-(4-(2-(1H-indazol-6- yl)ethynyl)phenoxy)-1H-1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#Cc1ccc2cn[nH]c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581246 (5-(3-(2-(thiazol-2- yl)ethynyl)phenoxy)-1H-1,2,3-...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1nccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581151 (5-(4-((1-methyl-6-oxo-1,6- dihydropyridin-3- yl)...) Show SMILES Cn1cc(ccc1=O)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581158 (5-(4-((1-methyl-2-oxo-1,2- dihydropyridin-4- yl)...) Show SMILES Cn1ccc(cc1=O)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581160 (5-(3-fluoro-5-(2- phenylethynyl)phenoxy)-1H- 1,2...) Show SMILES OC(=O)c1nn[nH]c1Oc1cc(F)cc(c1)C#Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581165 (5-(4-(trifluoromethyl)-3-(2- phenylethynyl)phenox...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(c(c1)C#Cc1ccccc1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581168 (5-(4-fluoro-3-(2-(4- (methylsulfonyl)phenyl)ethyn...) Show SMILES CS(=O)(=O)c1ccc(cc1)C#Cc1cc(Oc2[nH]nnc2C(O)=O)ccc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581169 (5-(4-fluoro-3-(2-(3- (methylsulfonyl)phenyl)ethyn...) Show SMILES CS(=O)(=O)c1cccc(c1)C#Cc1cc(Oc2[nH]nnc2C(O)=O)ccc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581173 (5-(4-((3- cyanophenyl)ethynyl)-3- fluorophenoxy)...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(F)c(c1)C#Cc1cccc(c1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581174 (5-(3-fluoro-4-(2-(4- (methylsulfonyl)phenyl)ethyn...) Show SMILES CS(=O)(=O)c1ccc(cc1)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581175 (5-(3-fluoro-4-(2-(3- (methylsulfonyl)phenyl)ethyn...) Show SMILES CS(=O)(=O)c1cccc(c1)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581179 (4-(3-((3-cyanophenyl) ethynyl)-5-fluorophenoxy)- ...) Show SMILES OC(=O)c1nn[nH]c1Oc1cc(F)cc(c1)C#Cc1cccc(c1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581181 (5-(3-(2-(3-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581195 (5-(3-(2-(4-chlorophenyl) ethynyl)phenoxy)-1H-1,2,...) Show SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581257 (5-(4-(3-(4-fluorophenyl)prop- 1-ynyl)phenoxy)-1H-...) Show SMILES OC(=O)c1nn[nH]c1Oc1ccc(cc1)C#CCc1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM581218 (5-(4-(2-(1-methyl-1H-indazol- 4-yl)ethynyl)phenox...) Show SMILES Cn1ncc2c(cccc12)C#Cc1ccc(Oc2[nH]nnc2C(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T157GG
					More data for this Ligand-Target Pair
2-Hydroxyacid oxidase 1 (Homo sapiens (Human))	BDBM560931 (5-((3',5'-dichloro-[1,1'- biphenyl]-3-yl)oxy)- 1H-...) Show SMILES Clc1cc(Cl)cc(c1)-c1cccc(Oc2cnn[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy...				Citation and Details BindingDB Entry DOI: 10.7270/Q2D221VD
					More data for this Ligand-Target Pair

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