Compile Data Set for Download or QSAR

Found 14 hits of ec50 for UniProtKB: Q63371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50199173 (((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O Show InChI InChI=1S/C9H13BrN2O12P2/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(23-8)2-22-26(20,21)24-25(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at rat P2Y6 receptor assessed as IP accumulation by SPA				J Med Chem 49: 7076-87 (2006) Article DOI: 10.1021/jm060848j BindingDB Entry DOI: 10.7270/Q2SN09RW
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50199173 (((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O Show InChI InChI=1S/C9H13BrN2O12P2/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(23-8)2-22-26(20,21)24-25(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay				J Med Chem 53: 1673-85 (2010) Article DOI: 10.1021/jm901450d BindingDB Entry DOI: 10.7270/Q2ZW1MWR
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50118239 (CHEMBL130266 | UDP | Uridine diphosphate | uridine...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation ...				Eur J Med Chem 44: 1525-36 (2009) Article DOI: 10.1016/j.ejmech.2008.07.015 BindingDB Entry DOI: 10.7270/Q2W37X7P
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50118239 (CHEMBL130266 | UDP | Uridine diphosphate | uridine...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364065 (CHEMBL1950676) Show SMILES [BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H27BN4O19P3/c19-43(32,37-5-7-11(26)13(28)15(39-7)22-3-1-9(24)20-17(22)30)41-45(35,36)42-44(33,34)38-6-8-12(27)14(29)16(40-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,20,24,30)(H,21,25,31)/q-1/p-2/t7-,8-,11-,12-,13-,14-,15-,16-,43?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364065 (CHEMBL1950676) Show SMILES [BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H27BN4O19P3/c19-43(32,37-5-7-11(26)13(28)15(39-7)22-3-1-9(24)20-17(22)30)41-45(35,36)42-44(33,34)38-6-8-12(27)14(29)16(40-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,20,24,30)(H,21,25,31)/q-1/p-2/t7-,8-,11-,12-,13-,14-,15-,16-,43?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364069 (CHEMBL1950673) Show SMILES [BH3-]P(=O)(OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C19H29BN7O20P4/c20-48(34,45-49(35,36)41-3-8-12(30)14(32)18(44-8)27-6-24-10-15(21)22-5-23-16(10)27)46-51(39,40)47-50(37,38)42-4-7-11(29)13(31)17(43-7)26-2-1-9(28)25-19(26)33/h1-2,5-8,11-14,17-18,29-32H,3-4H2,20H3,(H,35,36)(H,37,38)(H,39,40)(H2,21,22,23)(H,25,28,33)/q-1/p-3/t7-,8-,11-,12-,13-,14-,17-,18-,48?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364069 (CHEMBL1950673) Show SMILES [BH3-]P(=O)(OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C19H29BN7O20P4/c20-48(34,45-49(35,36)41-3-8-12(30)14(32)18(44-8)27-6-24-10-15(21)22-5-23-16(10)27)46-51(39,40)47-50(37,38)42-4-7-11(29)13(31)17(43-7)26-2-1-9(28)25-19(26)33/h1-2,5-8,11-14,17-18,29-32H,3-4H2,20H3,(H,35,36)(H,37,38)(H,39,40)(H2,21,22,23)(H,25,28,33)/q-1/p-3/t7-,8-,11-,12-,13-,14-,17-,18-,48?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364073 (CHEMBL1950672) Show SMILES [BH3-]P(=O)(OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H28BN4O22P4/c19-46(32,43-47(33,34)39-5-7-11(26)13(28)15(41-7)22-3-1-9(24)20-17(22)30)44-49(37,38)45-48(35,36)40-6-8-12(27)14(29)16(42-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,37,38)(H,20,24,30)(H,21,25,31)/q-1/p-3/t7-,8-,11-,12-,13-,14-,15-,16-,46?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364073 (CHEMBL1950672) Show SMILES [BH3-]P(=O)(OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H28BN4O22P4/c19-46(32,43-47(33,34)39-5-7-11(26)13(28)15(41-7)22-3-1-9(24)20-17(22)30)44-49(37,38)45-48(35,36)40-6-8-12(27)14(29)16(42-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,37,38)(H,20,24,30)(H,21,25,31)/q-1/p-3/t7-,8-,11-,12-,13-,14-,15-,16-,46?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364070 (CHEMBL1950674) Show SMILES [BH3-]P(=O)(OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C19H29BN7O20P4/c20-48(34,45-49(35,36)41-3-7-11(29)13(31)17(43-7)26-2-1-9(28)25-19(26)33)46-51(39,40)47-50(37,38)42-4-8-12(30)14(32)18(44-8)27-6-24-10-15(21)22-5-23-16(10)27/h1-2,5-8,11-14,17-18,29-32H,3-4H2,20H3,(H,35,36)(H,37,38)(H,39,40)(H2,21,22,23)(H,25,28,33)/q-1/p-3/t7-,8-,11-,12-,13-,14-,17-,18-,48?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364070 (CHEMBL1950674) Show SMILES [BH3-]P(=O)(OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C19H29BN7O20P4/c20-48(34,45-49(35,36)41-3-7-11(29)13(31)17(43-7)26-2-1-9(28)25-19(26)33)46-51(39,40)47-50(37,38)42-4-8-12(30)14(32)18(44-8)27-6-24-10-15(21)22-5-23-16(10)27/h1-2,5-8,11-14,17-18,29-32H,3-4H2,20H3,(H,35,36)(H,37,38)(H,39,40)(H2,21,22,23)(H,25,28,33)/q-1/p-3/t7-,8-,11-,12-,13-,14-,17-,18-,48?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364066 (CHEMBL1950678) Show SMILES [BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H28BN4O22P4/c19-46(32,39-5-7-11(26)13(28)15(41-7)22-3-1-9(24)20-17(22)30)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(27)14(29)16(42-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,37,38)(H,20,24,30)(H,21,25,31)/q-1/p-3/t7-,8-,11-,12-,13-,14-,15-,16-,46?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.61E+4	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair
P2Y purinoceptor 6 (Rattus norvegicus)	BDBM50364066 (CHEMBL1950678) Show SMILES [BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C18H28BN4O22P4/c19-46(32,39-5-7-11(26)13(28)15(41-7)22-3-1-9(24)20-17(22)30)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(27)14(29)16(42-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,37,38)(H,20,24,30)(H,21,25,31)/q-1/p-3/t7-,8-,11-,12-,13-,14-,15-,16-,46?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.61E+4	n/a	n/a	n/a	n/a
Bar-Ilan University Curated by ChEMBL					Assay Description Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...				J Med Chem 55: 437-48 (2012) Article DOI: 10.1021/jm2013198 BindingDB Entry DOI: 10.7270/Q2Z60PJT
					More data for this Ligand-Target Pair