Compile Data Set for Download or QSAR

Found 42 hits of ic50 for UniProtKB: Q9H422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563555 (CHEMBL4750420) Show SMILES c1n[nH]cc1-c1ccc2occ(-c3ccc4ccccc4c3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50172243 (CHEMBL3103192) Show SMILES CN(CCN)c1ccc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)cc1NC(C)=O Show InChI InChI=1S/C21H25N9O/c1-13(31)25-17-9-16(5-6-18(17)29(2)8-7-22)26-19-10-20(27-15-3-4-15)30-21(28-19)14(11-23)12-24-30/h5-6,9-10,12,15,27H,3-4,7-8,22H2,1-2H3,(H,25,31)(H,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Hipk3 (unknown origin) by quantitative PCR				ACS Med Chem Lett 7: 300-5 (2016) Article DOI: 10.1021/acsmedchemlett.5b00452 BindingDB Entry DOI: 10.7270/Q2C53NRM
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human HIPK3 in presence of ATP at Km concentration by radiometric filter-binding assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112770 BindingDB Entry DOI: 10.7270/Q2DN48PP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant HIPK3 by radiometric assay				J Med Chem 54: 635-54 (2011) Article DOI: 10.1021/jm101251q BindingDB Entry DOI: 10.7270/Q2J67H7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563541 (CHEMBL4743730) Show SMILES CC(=C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563556 (CHEMBL4743939) Show SMILES COc1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM17055 ((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...) Show SMILES CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21 |r,t:10| Show InChI InChI=1S/C28H28N4O3/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HIPK3 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HIPK3 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50242737 ((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1 |r| Show InChI InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HIPK3 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HIPK3 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563538 (CHEMBL4797457) Show SMILES Cn1cc(cn1)-c1cccc(c1)-c1coc2ccc(nc12)-c1cnn(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563554 (CHEMBL4790030) Show SMILES c1n[nH]cc1-c1ccc2occ(-c3ccccc3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563539 (CHEMBL4762964) Show SMILES Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3cc[nH]n3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50560704 (CHEMBL4754195) Show SMILES Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3ccncc3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50560704 (CHEMBL4754195) Show SMILES Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3ccncc3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HIPK3 by radiometric assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00898 BindingDB Entry DOI: 10.7270/Q2GQ72GZ
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563537 (CHEMBL4789951) Show SMILES Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3cn[nH]c3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HIPK3 using MBP as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563534 (CHEMBL4778153) Show SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563535 (CHEMBL4791451) Show SMILES Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)C3CCNCC3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563540 (CHEMBL4740998) Show SMILES CC1(CC1)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	441	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563533 (CHEMBL4777288) Show SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	476	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563536 (CHEMBL4741919) Show SMILES CN1CCC(CC1)c1cccc(c1)-c1coc2ccc(nc12)-c1cnn(C)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	692	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human HIPK3 using MBP as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563551 (CHEMBL4777533) Show SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1nn[nH]n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563544 (CHEMBL4778370) Show SMILES c1n[nH]cc1-c1ccc2occ(-c3ccc(cc3)-c3ccccc3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	807	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563543 (CHEMBL4794825) Show SMILES CC(C)Cc1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563553 (CHEMBL4795812) Show SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cnn(CCN2CCOCC2)c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563552 (CHEMBL4747520) Show SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cnsc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563550 (CHEMBL4793177) Show SMILES Cn1ccc(n1)-c1ccc2occ(-c3ccc(cc3)C(C)(C)C)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563548 (CHEMBL4790254) Show SMILES Cn1cc(nn1)-c1ccc2occ(-c3ccc(cc3)C(C)(C)C)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563547 (CHEMBL4747210) Show SMILES Cn1cc(cn1)-c1ccc2occ(-c3ccc(cc3)C(C)(C)C)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563546 (CHEMBL4758047) Show SMILES C1C2CC3CC1CC(C2)(C3)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 |TLB:0:1:9:6.5.4,0:5:8.1.2:9,4:3:8:6.0.5,THB:4:5:8:2.3.9| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563545 (CHEMBL4777540) Show SMILES C1CCC(CC1)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563542 (CHEMBL4789373) Show SMILES C(c1ccccc1)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50563549 (CHEMBL4800422) Show SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cc[nH]n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113299 BindingDB Entry DOI: 10.7270/Q2KD22MP
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50135286 (CHEMBL3745885) Show SMILES Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1F Show InChI InChI=1S/C22H15F2N5O3S/c1-29-20-13(9-19(21(29)30)33(31,32)18-5-2-14(23)10-16(18)24)11-26-22(28-20)27-15-3-4-17-12(8-15)6-7-25-17/h2-11,25H,1H3,(H,26,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human HIPK3 using MBP as substrate				Bioorg Med Chem 24: 521-44 (2016) Article DOI: 10.1016/j.bmc.2015.11.045 BindingDB Entry DOI: 10.7270/Q24Q7WT8
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50001733 (CHEMBL3133821) Show SMILES Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1 Show InChI InChI=1S/C17H13N3O/c21-12-5-3-4-11(10-12)19-15-8-9-18-17-16(15)13-6-1-2-7-14(13)20-17/h1-10,21H,(H2,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of human HIPK3				Bioorg Med Chem Lett 24: 1948-51 (2014) Article DOI: 10.1016/j.bmcl.2014.03.002 BindingDB Entry DOI: 10.7270/Q2TM7CN0
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50519662 (CHEMBL4438748) Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1 Show InChI InChI=1S/C26H23N3O5/c1-29(2)20-8-6-17(7-9-20)26(32)28-19-5-3-4-18(14-19)27-25(31)16-34-21-10-11-22-23(30)12-13-33-24(22)15-21/h3-15H,16H2,1-2H3,(H,27,31)(H,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant HIPK3 (161 to 562 residues) using myelin basic protein as substrate after 40 mins by [gamma-33ATP] radiometric assay				J Med Chem 62: 10691-10710 (2019) Article DOI: 10.1021/acs.jmedchem.9b01143 BindingDB Entry DOI: 10.7270/Q2MC93FG
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM13533 (1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ansaris Curated by ChEMBL					Assay Description Inhibition of HIPK3				Bioorg Med Chem Lett 21: 7155-65 (2011) Article DOI: 10.1016/j.bmcl.2011.09.078 BindingDB Entry DOI: 10.7270/Q2NC61NH
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50359359 (CHEMBL1929238) Show SMILES CN(C)CCN1CCN(CCC1=O)C(=O)c1cc(sc1NC(=O)Nc1cccc(Cl)c1Cl)C(C)(C)C Show InChI InChI=1S/C25H33Cl2N5O3S/c1-25(2,3)19-15-16(22(36-19)29-24(35)28-18-8-6-7-17(26)21(18)27)23(34)32-10-9-20(33)31(13-14-32)12-11-30(4)5/h6-8,15H,9-14H2,1-5H3,(H2,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ansaris Curated by ChEMBL					Assay Description Inhibition of HIPK3				Bioorg Med Chem Lett 21: 7155-65 (2011) Article DOI: 10.1016/j.bmcl.2011.09.078 BindingDB Entry DOI: 10.7270/Q2NC61NH
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	BDBM50537742 (CHEMBL4634634 | US11179389, Compound 1-14) Show SMILES C[C@@H]1C[C@H]1C(=O)N1CCN(C[C@H]1C)c1cnc(C#N)c(n1)-c1cnn(C)c1 |r| Show InChI InChI=1S/C19H23N7O/c1-12-6-15(12)19(27)26-5-4-25(10-13(26)2)17-9-21-16(7-20)18(23-17)14-8-22-24(3)11-14/h8-9,11-13,15H,4-6,10H2,1-3H3/t12-,13-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged HIPK3 catalytic domain expressed in baculovirus expression system using serine/threonine-9 peptide as subs...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126715 BindingDB Entry DOI: 10.7270/Q2HM5CZG
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 3 (Homo sapiens (Human))	CHEMBL5288779 Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair