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Compile Data Set for Download or QSAR

Found 289 hits of ic50 for UniProtKB: Q92831   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512964
PNG
(CHEMBL4574669)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc2OCCOc2c1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C21H25N5O3/c1-25-11-14(13-3-4-17-18(10-13)29-8-7-28-17)9-15(12-25)23-21-24-16-5-6-22-19(16)20(27)26(21)2/h3-6,10,14-15,22H,7-9,11-12H2,1-2H3,(H,23,24)/t14-,15+/m0/s1
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n/an/a 7n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512976
PNG
(CHEMBL4543497)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc(Oc2ccccc2)cc1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C25H27N5O2/c1-29-15-18(17-8-10-21(11-9-17)32-20-6-4-3-5-7-20)14-19(16-29)27-25-28-22-12-13-26-23(22)24(31)30(25)2/h3-13,18-19,26H,14-16H2,1-2H3,(H,27,28)/t18-,19+/m0/s1
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n/an/a 10n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234932
PNG
(CHEMBL4103402 | US10239861, Example 20)
Show SMILES CC(C)C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C15H25ClN4O/c1-10(2)5-11-6-12(9-19(3)8-11)18-13-7-17-20(4)15(21)14(13)16/h7,10-12,18H,5-6,8-9H2,1-4H3/t11-,12+/m0/s1
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n/an/a 12.7n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234932
PNG
(CHEMBL4103402 | US10239861, Example 20)
Show SMILES CC(C)C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C15H25ClN4O/c1-10(2)5-11-6-12(9-19(3)8-11)18-13-7-17-20(4)15(21)14(13)16/h7,10-12,18H,5-6,8-9H2,1-4H3/t11-,12+/m0/s1
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of biotinylated small molecule ligand from His/FLAG-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) after 15 mins by Alph...

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234932
PNG
(CHEMBL4103402 | US10239861, Example 20)
Show SMILES CC(C)C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C15H25ClN4O/c1-10(2)5-11-6-12(9-19(3)8-11)18-13-7-17-20(4)15(21)14(13)16/h7,10-12,18H,5-6,8-9H2,1-4H3/t11-,12+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated ligand binding to FLAG epitope-fused/His-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) measured after 15 ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512967
PNG
(CHEMBL4449143)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc(OCc2ccccc2)cc1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C26H29N5O2/c1-30-15-20(19-8-10-22(11-9-19)33-17-18-6-4-3-5-7-18)14-21(16-30)28-26-29-23-12-13-27-24(23)25(32)31(26)2/h3-13,20-21,27H,14-17H2,1-2H3,(H,28,29)/t20-,21+/m0/s1
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n/an/a 14n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512958
PNG
(CHEMBL4439202)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc(OC(F)(F)F)cc1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C20H22F3N5O2/c1-27-10-13(12-3-5-15(6-4-12)30-20(21,22)23)9-14(11-27)25-19-26-16-7-8-24-17(16)18(29)28(19)2/h3-8,13-14,24H,9-11H2,1-2H3,(H,25,26)/t13-,14+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM311486
PNG
(CHEM-US-00192 | US10155764, Example 65B)
Show SMILES C[C@@H](Nc1nn(C)c(=O)c2cccnc12)[C@H](N(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C19H23N5O/c1-13(17(23(2)3)14-9-6-5-7-10-14)21-18-16-15(11-8-12-20-16)19(25)24(4)22-18/h5-13,17H,1-4H3,(H,21,22)/t13-,17+/m1/s1
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n/an/a 19n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of biotinylated small molecule ligand from His/FLAG-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) after 15 mins by Alph...

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM311486
PNG
(CHEM-US-00192 | US10155764, Example 65B)
Show SMILES C[C@@H](Nc1nn(C)c(=O)c2cccnc12)[C@H](N(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C19H23N5O/c1-13(17(23(2)3)14-9-6-5-7-10-14)21-18-16-15(11-8-12-20-16)19(25)24(4)22-18/h5-13,17H,1-4H3,(H,21,22)/t13-,17+/m1/s1
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n/an/a 19n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated ligand binding to FLAG epitope-fused/His-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) measured after 15 ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371542
PNG
(4-chloro-5-(((3R,5S)-1,5-dimethylpiperidin-3-yl)am...)
Show SMILES C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-9(7-16(2)6-8)15-10-5-14-17(3)12(18)11(10)13/h5,8-9,15H,4,6-7H2,1-3H3/t8-,9+/m0/s1
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n/an/a 21.5n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512960
PNG
(CHEMBL4545594)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1cccc(Br)c1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C19H22BrN5O/c1-24-10-13(12-4-3-5-14(20)8-12)9-15(11-24)22-19-23-16-6-7-21-17(16)18(26)25(19)2/h3-8,13,15,21H,9-11H2,1-2H3,(H,22,23)/t13-,15+/m0/s1
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n/an/a 22n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512965
PNG
(CHEMBL4453637)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1cccc(c1)-c1ccccc1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C25H27N5O/c1-29-15-20(19-10-6-9-18(13-19)17-7-4-3-5-8-17)14-21(16-29)27-25-28-22-11-12-26-23(22)24(31)30(25)2/h3-13,20-21,26H,14-16H2,1-2H3,(H,27,28)/t20-,21+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512966
PNG
(CHEMBL4570924)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc(O)cc1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C19H23N5O2/c1-23-10-13(12-3-5-15(25)6-4-12)9-14(11-23)21-19-22-16-7-8-20-17(16)18(26)24(19)2/h3-8,13-14,20,25H,9-11H2,1-2H3,(H,21,22)/t13-,14+/m0/s1
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n/an/a 30n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512954
PNG
(CHEMBL4527339)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc(Cl)c(c1)C(F)(F)F)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C20H21ClF3N5O/c1-28-9-12(11-3-4-15(21)14(8-11)20(22,23)24)7-13(10-28)26-19-27-16-5-6-25-17(16)18(30)29(19)2/h3-6,8,12-13,25H,7,9-10H2,1-2H3,(H,26,27)/t12-,13+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512968
PNG
(CHEMBL4454700)
Show SMILES COc1ccc(cc1)[C@H]1C[C@H](CN(C)C1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C20H25N5O2/c1-24-11-14(13-4-6-16(27-3)7-5-13)10-15(12-24)22-20-23-17-8-9-21-18(17)19(26)25(20)2/h4-9,14-15,21H,10-12H2,1-3H3,(H,22,23)/t14-,15+/m0/s1
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n/an/a 32n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371577
PNG
((S)-4-chloro-2-methyl-5-((1-methylazepan-3-yl)amin...)
Show SMILES CN1CCCC[C@@H](C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-16-6-4-3-5-9(8-16)15-10-7-14-17(2)12(18)11(10)13/h7,9,15H,3-6,8H2,1-2H3/t9-/m0/s1
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n/an/a 32.9n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371546
PNG
(US10239861, Example 26)
Show SMILES C[C@@H]1CC[C@H](CN1C)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-5-9(7-16(8)2)15-10-6-14-17(3)12(18)11(10)13/h6,8-9,15H,4-5,7H2,1-3H3/t8-,9-/m1/s1
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n/an/a 34.8n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512959
PNG
(CHEMBL4454766)
Show SMILES CCCCc1ccc(cc1)[C@H]1C[C@H](CN(C)C1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C23H31N5O/c1-4-5-6-16-7-9-17(10-8-16)18-13-19(15-27(2)14-18)25-23-26-20-11-12-24-21(20)22(29)28(23)3/h7-12,18-19,24H,4-6,13-15H2,1-3H3,(H,25,26)/t18-,19+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512980
PNG
(CHEMBL4570969)
Show SMILES C[C@H](Nc1nn2c(C)nnc2c2ccccc12)[C@@H](N(C)C)c1ccccc1 |r|
Show InChI InChI=1S/C21H24N6/c1-14(19(26(3)4)16-10-6-5-7-11-16)22-20-17-12-8-9-13-18(17)21-24-23-15(2)27(21)25-20/h5-14,19H,1-4H3,(H,22,25)/t14-,19+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371541
PNG
((racemic)-4-chloro-5-(((3RS,5SR)-1,5-dimethylpiper...)
Show SMILES CC1CC(CN(C)C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-9(7-16(2)6-8)15-10-5-14-17(3)12(18)11(10)13/h5,8-9,15H,4,6-7H2,1-3H3
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n/an/a 36.5n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
Show InChI InChI=1S/C17H21BrN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1
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n/an/a 40n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assay

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512975
PNG
(CHEMBL4471748)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C19H23N5O/c1-23-11-14(13-6-4-3-5-7-13)10-15(12-23)21-19-22-16-8-9-20-17(16)18(25)24(19)2/h3-9,14-15,20H,10-12H2,1-2H3,(H,21,22)/t14-,15+/m0/s1
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n/an/a 41n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512979
PNG
(CHEMBL4457684)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc2ccccc2c1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C23H25N5O/c1-27-13-18(17-8-7-15-5-3-4-6-16(15)11-17)12-19(14-27)25-23-26-20-9-10-24-21(20)22(29)28(23)2/h3-11,18-19,24H,12-14H2,1-2H3,(H,25,26)/t18-,19+/m0/s1
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371549
PNG
(US10239861, Example 29)
Show SMILES C[C@H]1CC[C@H](CN1C)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-5-9(7-16(8)2)15-10-6-14-17(3)12(18)11(10)13/h6,8-9,15H,4-5,7H2,1-3H3/t8-,9+/m0/s1
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n/an/a 48.5n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234932
PNG
(CHEMBL4103402 | US10239861, Example 20)
Show SMILES CC(C)C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C15H25ClN4O/c1-10(2)5-11-6-12(9-19(3)8-11)18-13-7-17-20(4)15(21)14(13)16/h7,10-12,18H,5-6,8-9H2,1-4H3/t11-,12+/m0/s1
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n/an/a 49.6n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371533
PNG
(4-bromo-2-methyl-5-((1-methylazepan-3-yl)amino)pyr...)
Show SMILES CN1CCCCC(C1)Nc1cnn(C)c(=O)c1Br
Show InChI InChI=1S/C12H19BrN4O/c1-16-6-4-3-5-9(8-16)15-10-7-14-17(2)12(18)11(10)13/h7,9,15H,3-6,8H2,1-2H3
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n/an/a 51n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234945
PNG
(CHEMBL4061142 | US10239861, Example 59)
Show SMILES CN1CCC[C@@H](C1)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C11H17ClN4O/c1-15-5-3-4-8(7-15)14-9-6-13-16(2)11(17)10(9)12/h6,8,14H,3-5,7H2,1-2H3/t8-/m0/s1
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n/an/a 51.2n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
Show InChI InChI=1S/C17H21BrN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1
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n/an/a 60n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of Halo-tagged histone H3.3 from NanoLuc-tagged full length human PCAF bromodomain expressed in HEK293 cells after 18 hrs by NanoBRET as...

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371545
PNG
(4-chloro-5-((1,6-dimethylpiperidin-3-yl)amino)-2-m...)
Show SMILES CC1CCC(CN1C)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-5-9(7-16(8)2)15-10-6-14-17(3)12(18)11(10)13/h6,8-9,15H,4-5,7H2,1-3H3
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n/an/a 60n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371521
PNG
(4-chloro-2-methyl-5-((1-methylazepan-3-yl)amino)py...)
Show SMILES CN1CCCCC(C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-16-6-4-3-5-9(8-16)15-10-7-14-17(2)12(18)11(10)13/h7,9,15H,3-6,8H2,1-2H3
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n/an/a 62n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
Show InChI InChI=1S/C17H21BrN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1
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n/an/a 63n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of Halo-tagged histone H3.3 from NanoLuc-tagged full length human PCAF bromodomain expressed in HEK293 cells after 18 hrs by NanoBRET as...

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234931
PNG
(CHEMBL4088595)
Show SMILES C[C@H](Nc1nn(C)c(=O)n(C)c1=O)[C@@H](N(C)C)c1ccc(cc1)S(=O)(=O)c1ccccc1 |r|
Show InChI InChI=1S/C22H27N5O4S/c1-15(23-20-21(28)26(4)22(29)27(5)24-20)19(25(2)3)16-11-13-18(14-12-16)32(30,31)17-9-7-6-8-10-17/h6-15,19H,1-5H3,(H,23,24)/t15-,19+/m0/s1
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n/an/a 70n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated ligand binding to FLAG epitope-fused/His-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) measured after 15 ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234931
PNG
(CHEMBL4088595)
Show SMILES C[C@H](Nc1nn(C)c(=O)n(C)c1=O)[C@@H](N(C)C)c1ccc(cc1)S(=O)(=O)c1ccccc1 |r|
Show InChI InChI=1S/C22H27N5O4S/c1-15(23-20-21(28)26(4)22(29)27(5)24-20)19(25(2)3)16-11-13-18(14-12-16)32(30,31)17-9-7-6-8-10-17/h6-15,19H,1-5H3,(H,23,24)/t15-,19+/m0/s1
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n/an/a 70n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of biotinylated small molecule ligand from His/FLAG-tagged PCAF bromodomain (719 to 832 residues) (unknown origin) after 15 mins by Alph...

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512962
PNG
(CHEMBL4565832)
Show SMILES [H][C@]12CCC[C@]([H])(C[C@@H](C1)Nc1nc3cc[nH]c3c(=O)n1C)N2C |r,TLB:23:22:3.2.4:8.7.9|
Show InChI InChI=1S/C16H23N5O/c1-20-11-4-3-5-12(20)9-10(8-11)18-16-19-13-6-7-17-14(13)15(22)21(16)2/h6-7,10-12,17H,3-5,8-9H2,1-2H3,(H,18,19)/t10-,11+,12-
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n/an/a 73n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234939
PNG
(CHEMBL4084253)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C17H21ClN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1
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n/an/a 79n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assay

J Med Chem 60: 695-709 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01566
BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50234943
PNG
(CHEMBL4099456 | US10239861, Example 3)
Show SMILES CN1CCCC(C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C11H17ClN4O/c1-15-5-3-4-8(7-15)14-9-6-13-16(2)11(17)10(9)12/h6,8,14H,3-5,7H2,1-2H3
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n/an/a 85n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371527
PNG
((R)-5-((1-benzylpiperidin-3-yl)amino)-4-chloro-2-m...)
Show SMILES Cn1ncc(N[C@@H]2CCCN(Cc3ccccc3)C2)c(Cl)c1=O
Show InChI InChI=1S/C17H21ClN4O/c1-21-17(23)16(18)15(10-19-21)20-14-8-5-9-22(12-14)11-13-6-3-2-4-7-13/h2-4,6-7,10,14,20H,5,8-9,11-12H2,1H3/t14-/m1/s1
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n/an/a 85.6n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371564
PNG
(4-chloro-5-[[1-[[3-(difluoromethoxy)phenyl]methyl]...)
Show SMILES Cn1ncc(NC2CCCN(Cc3cccc(OC(F)F)c3)C2)c(Cl)c1=O
Show InChI InChI=1S/C18H21ClF2N4O2/c1-24-17(26)16(19)15(9-22-24)23-13-5-3-7-25(11-13)10-12-4-2-6-14(8-12)27-18(20)21/h2,4,6,8-9,13,18,23H,3,5,7,10-11H2,1H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371559
PNG
((R)-4-chloro-2-methyl-5-((2,3,4,5-tetrahydro-1H-be...)
Show SMILES Cn1ncc(Cl)c(N[C@@H]2Cc3ccccc3CNC2=O)c1=O |r|
Show InChI InChI=1S/C15H15ClN4O2/c1-20-15(22)13(11(16)8-18-20)19-12-6-9-4-2-3-5-10(9)7-17-14(12)21/h2-5,8,12,19H,6-7H2,1H3,(H,17,21)/t12-/m1/s1
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512964
PNG
(CHEMBL4574669)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccc2OCCOc2c1)Nc1nc2cc[nH]c2c(=O)n1C |r|
Show InChI InChI=1S/C21H25N5O3/c1-25-11-14(13-3-4-17-18(10-13)29-8-7-28-17)9-15(12-25)23-21-24-16-5-6-22-19(16)20(27)26(21)2/h3-6,10,14-15,22H,7-9,11-12H2,1-2H3,(H,23,24)/t14-,15+/m0/s1
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n/an/a 118n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of Halo-tagged histone H3.3 binding to N-terminal Nano luciferase-fused full-length PCAF (unknown origin) expressed in HEK293T cells co-ex...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM50512961
PNG
(CHEMBL4541223)
Show SMILES [H][C@]12CCC[C@]([H])(C[C@H](C1)Nc1nc3cc[nH]c3c(=O)n1C)N2 |r|
Show InChI InChI=1S/C15H21N5O/c1-20-14(21)13-12(5-6-16-13)19-15(20)18-11-7-9-3-2-4-10(8-11)17-9/h5-6,9-11,16-17H,2-4,7-8H2,1H3,(H,18,19)/t9-,10+,11-
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Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of biotinylated peptide binding to human GST-tagged PCAF bromodomain expressed in Escherichia coli Rosetta (DE3) measured after 15 hrs by ...

J Med Chem 62: 4526-4542 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00096
BindingDB Entry DOI: 10.7270/Q2862KS8
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371576
PNG
(4-chloro-5-[[1-[(4-fluorophenyl)methyl]-3-piperidy...)
Show SMILES Cn1ncc(NC2CCCN(Cc3ccc(F)cc3)C2)c(Cl)c1=O
Show InChI InChI=1S/C17H20ClFN4O/c1-22-17(24)16(18)15(9-20-22)21-14-3-2-8-23(11-14)10-12-4-6-13(19)7-5-12/h4-7,9,14,21H,2-3,8,10-11H2,1H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371547
PNG
(US10239861, Example 27)
Show SMILES C[C@@H]1CC[C@@H](CN1C)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-5-9(7-16(8)2)15-10-6-14-17(3)12(18)11(10)13/h6,8-9,15H,4-5,7H2,1-3H3/t8-,9+/m1/s1
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371552
PNG
(4-chloro-5-((1-isopropylpiperidin-3-yl)amino)-2-me...)
Show SMILES CC(C)N1CCCC(C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C13H21ClN4O/c1-9(2)18-6-4-5-10(8-18)16-11-7-15-17(3)13(19)12(11)14/h7,9-10,16H,4-6,8H2,1-3H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371554
PNG
(US10239861, Example 34 | racemic-5-((1-benzylpiper...)
Show SMILES Cn1ncc(NC2CCCN(Cc3ccccc3)C2)c(Cl)c1=O
Show InChI InChI=1S/C17H21ClN4O/c1-21-17(23)16(18)15(10-19-21)20-14-8-5-9-22(12-14)11-13-6-3-2-4-7-13/h2-4,6-7,10,14,20H,5,8-9,11-12H2,1H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371560
PNG
(4-chloro-2-methyl-5-((1-methylazocan-3-yl)amino)py...)
Show SMILES CN1CCCCCC(C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C13H21ClN4O/c1-17-7-5-3-4-6-10(9-17)16-11-8-15-18(2)13(19)12(11)14/h8,10,16H,3-7,9H2,1-2H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371521
PNG
(4-chloro-2-methyl-5-((1-methylazepan-3-yl)amino)py...)
Show SMILES CN1CCCCC(C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-16-6-4-3-5-9(8-16)15-10-7-14-17(2)12(18)11(10)13/h7,9,15H,3-6,8H2,1-2H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371544
PNG
(4-chloro-2-methyl-5-((1-methyl-5-phenylpiperidin-3...)
Show SMILES CN1CC(CC(C1)c1ccccc1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C17H21ClN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371578
PNG
((R)-4-chloro-2-methyl-5-((1-methylazepan-3-yl)amin...)
Show SMILES CN1CCCC[C@H](C1)Nc1cnn(C)c(=O)c1Cl
Show InChI InChI=1S/C12H19ClN4O/c1-16-6-4-3-5-9(8-16)15-10-7-14-17(2)12(18)11(10)13/h7,9,15H,3-6,8H2,1-2H3/t9-/m1/s1
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371548
PNG
(US10239861, Example 28)
Show SMILES C[C@H]1CC[C@@H](CN1C)Nc1cnn(C)c(=O)c1Cl |r|
Show InChI InChI=1S/C12H19ClN4O/c1-8-4-5-9(7-16(8)2)15-10-6-14-17(3)12(18)11(10)13/h6,8-9,15H,4-5,7H2,1-3H3/t8-,9-/m0/s1
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GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair
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