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Compile Data Set for Download or QSAR

Found 8 hits of ec50 data for polymerid = 50003913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304337
PNG
(2-(2-Nitro-naphtho[2,1-b]furan-1-yl)-ethanol | 2-(...)
Show SMILES OCCc1c(oc2ccc3ccccc3c12)[N+]([O-])=O
Show InChI InChI=1S/C14H11NO4/c16-8-7-11-13-10-4-2-1-3-9(10)5-6-12(13)19-14(11)15(17)18/h1-6,16H,7-8H2
PDB
MMDB

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PubMed
n/an/an/an/a 1.22E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304338
PNG
(1-Methyl-2-nitro-naphtho[2,1-b]furan | 1-methyl-2-...)
Show SMILES Cc1c(oc2ccc3ccccc3c12)[N+]([O-])=O
Show InChI InChI=1S/C13H9NO3/c1-8-12-10-5-3-2-4-9(10)6-7-11(12)17-13(8)14(15)16/h2-7H,1H3
PDB
MMDB

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PubMed
n/an/an/an/a 1.28E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM22594
PNG
(7-methoxy-4-nitro-5-oxatricyclo[7.4.0.0^{2,6}]trid...)
Show SMILES COc1cc2ccccc2c2cc(oc12)[N+]([O-])=O
Show InChI InChI=1S/C13H9NO4/c1-17-11-6-8-4-2-3-5-9(8)10-7-12(14(15)16)18-13(10)11/h2-7H,1H3
PDB
MMDB

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PubMed
n/an/an/an/a 1.47E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304336
PNG
(2-Nitro-naphtho[2,1-b]furan-7-ol | 2-nitronaphtho[...)
Show SMILES Oc1ccc2c3cc(oc3ccc2c1)[N+]([O-])=O
Show InChI InChI=1S/C12H7NO4/c14-8-2-3-9-7(5-8)1-4-11-10(9)6-12(17-11)13(15)16/h1-6,14H
PDB
MMDB

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n/an/an/an/a 1.95E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304340
PNG
(2-Nitro-naphtho[2,1-b]furan | 2-nitronaphtho[2,1-b...)
Show SMILES [O-][N+](=O)c1cc2c(ccc3ccccc23)o1
Show InChI InChI=1S/C12H7NO3/c14-13(15)12-7-10-9-4-2-1-3-8(9)5-6-11(10)16-12/h1-7H
PDB
MMDB

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PubMed
n/an/an/an/a 2.09E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304339
PNG
(8-Methoxy-2-nitro-naphtho[2,1-b]furan | 8-methoxy-...)
Show SMILES COc1ccc2ccc3oc(cc3c2c1)[N+]([O-])=O
Show InChI InChI=1S/C13H9NO4/c1-17-9-4-2-8-3-5-12-11(10(8)6-9)7-13(18-12)14(15)16/h2-7H,1H3
PDB
MMDB

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PubMed
n/an/an/an/a 2.33E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304341
PNG
(7-Methoxy-2-nitro-naphtho[2,1-b]furan | 7-methoxy-...)
Show SMILES COc1ccc2c3cc(oc3ccc2c1)[N+]([O-])=O
Show InChI InChI=1S/C13H9NO4/c1-17-9-3-4-10-8(6-9)2-5-12-11(10)7-13(18-12)14(15)16/h2-7H,1H3
PDB
MMDB

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KEGG

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Purchase

CHEMBL
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UniChem

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Article
PubMed
n/an/an/an/a 2.57E+3n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair
Hepatocyte nuclear factor 4-alpha


(Homo sapiens (Human))
BDBM50304342
PNG
(CHEMBL611816 | naphtho[2,1-b]furan-2-carboxamide)
Show SMILES NC(=O)c1cc2c(ccc3ccccc23)o1
Show InChI InChI=1S/C13H9NO2/c14-13(15)12-7-10-9-4-2-1-3-8(9)5-6-11(10)16-12/h1-7H,(H2,14,15)
PDB
MMDB

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KEGG

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CHEMBL
PC cid
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UniChem

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Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Universit£ de Rennes 1

Curated by ChEMBL


Assay Description
Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells cotransfected with LexADBD assessed as increase i...


Bioorg Med Chem 17: 7021-30 (2009)

More data for this
Ligand-Target Pair