Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50446088 (CHEMBL3108870) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Competitive inhibition Trypanosoma brucei PFK using fructose-6-phosphate as substrate by Line-weaver Burk plot analysis | ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50446088 (CHEMBL3108870) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Mixed type inhibition Trypanosoma brucei PFK using ATP as substrate by Line-weaver Burk plot analysis | ACS Med Chem Lett 5: 12-7 (2014) Article DOI: 10.1021/ml400259d BindingDB Entry DOI: 10.7270/Q2X34ZX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50320388 (CHEMBL1083627 | polysin) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Yaound£ I Curated by ChEMBL | Assay Description Competitive reversible inhibition of Trypanosoma brucei PFK expressed in Escherichia coli using fructose-6-phosphate by spectrophotometry analysis | Bioorg Med Chem Lett 20: 3495-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.145 BindingDB Entry DOI: 10.7270/Q2HH6K8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) | BDBM50320385 ((4aR,6aR,12bS)-4,4,6a,12b-Tetramethyl-1,4a,5,6,6a,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Yaound£ I Curated by ChEMBL | Assay Description Competitive reversible inhibition of Trypanosoma brucei PFK expressed in Escherichia coli using fructose-6-phosphate by spectrophotometry analysis | Bioorg Med Chem Lett 20: 3495-8 (2010) Article DOI: 10.1016/j.bmcl.2010.04.145 BindingDB Entry DOI: 10.7270/Q2HH6K8B | |||||||||||
More data for this Ligand-Target Pair |