Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50569664 (CHEMBL4859451) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00096 BindingDB Entry DOI: 10.7270/Q2B2802B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50598494 (CHEMBL5171022) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00172 BindingDB Entry DOI: 10.7270/Q29G5RT0 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548828 (WO2022098806, Compound 2-89) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529791 (US11203591, Example 198) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548859 (WO2022098806, Compound 2-120) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548847 (WO2022098806, Compound 2-108) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548834 (WO2022098806, Compound 2-180 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548817 (WO2022098806, Compound 2-78) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548823 (WO2022098806, Compound 2-84) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548829 (WO2022098806, Compound 2-179 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548850 (WO2022098806, Compound 2-111) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548860 (WO2022098806, Compound 2-121) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548727 (WO2022098806, Compound 1-123) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529832 (US11203591, Example 238) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50569663 (CHEMBL4870155) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00096 BindingDB Entry DOI: 10.7270/Q2B2802B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548897 (WO2022098806, Compound 2-158) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548863 (WO2022098806, Compound 2-124 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548914 (WO2022098806, Compound 2-175) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548846 (WO2022098806, Compound 2-107 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548815 (WO2022098806, Compound 2-76) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548818 (WO2022098806, Compound 2-79) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529862 (US11203591, Example 268) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548821 (WO2022098806, Compound 2-82) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548824 (WO2022098806, Compound 2-85) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548867 (WO2022098806, Compound 2-128) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50569665 (CHEMBL4864568) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00096 BindingDB Entry DOI: 10.7270/Q2B2802B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50569667 (CHEMBL4848845) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00096 BindingDB Entry DOI: 10.7270/Q2B2802B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548909 (WO2022098806, Compound 2-170) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM509018 (US11071730, Example 125) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa... | Citation and Details BindingDB Entry DOI: 10.7270/Q2RR22CJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548820 (WO2022098806, Compound 2-81) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548822 (WO2022098806, Compound 2-83) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548825 (WO2022098806, Compound 2-86) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548829 (WO2022098806, Compound 2-179 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548830 (WO2022098806, Compound 2-91 | WO2022098806, Compou...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548835 (WO2022098806, Compound 2-102 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548856 (WO2022098806, Compound 2-117) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548858 (WO2022098806, Compound 2-119) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548763 (WO2022098806, Compound 2-114 | WO2022098806, Compo...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548878 (WO2022098806, Compound 2-139) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548728 (WO2022098806, Compound 1-124) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548738 (WO2022098806, Compound 1-134) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529840 (US11203591, Example 246) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529843 (US11203591, Example 249) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529845 (US11203591, Example 251) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529868 (US11203591, Example 274) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548722 (WO2022098806, Compound 1-118) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529833 (US11203591, Example 239) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM529602 (US11203591, Example 17) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ten nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well ProxiPlate (PerkinElmer #6008289). Five m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2833W6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM548922 (WO2022098806, Compound 2-183) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022098806 | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0RJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human)) | BDBM50598492 (CHEMBL5205694) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00172 BindingDB Entry DOI: 10.7270/Q29G5RT0 | ||||||||||||
More data for this Ligand-Target Pair |
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