Compile Data Set for Download or QSAR

Found 681 hits of ec50 data for polymerid = 50004101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96777 (MLS001181838 | N-[4-(phenylcarbamoylamino)phenyl]a...) Show SMILES CC(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C15H15N3O2/c1-11(19)16-13-7-9-14(10-8-13)18-15(20)17-12-5-3-2-4-6-12/h2-10H,1H3,(H,16,19)(H2,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>1.5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96729 (2-[5-[[anilino(oxo)methyl]amino]-1,3,4-thiadiazol-...) Show SMILES O=C(Cc1nnc(NC(=O)Nc2ccccc2)s1)Nc1ccccc1 Show InChI InChI=1S/C17H15N5O2S/c23-14(18-12-7-3-1-4-8-12)11-15-21-22-17(25-15)20-16(24)19-13-9-5-2-6-10-13/h1-10H,11H2,(H,18,23)(H2,19,20,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50581608 (CHEMBL5082760) Show SMILES NC[C@@H]1OCCc2ccsc12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM106582 (CHEMBL2206890 | US8586617, 23) Show SMILES CC(C)N(Cc1cnc[nH]1)c1cccc(Cl)c1 Show InChI InChI=1S/C13H16ClN3/c1-10(2)17(8-12-7-15-9-16-12)13-5-3-4-11(14)6-13/h3-7,9-10H,8H2,1-2H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.60	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 mins				Bioorg Med Chem Lett 22: 5244-8 (2012) Article DOI: 10.1016/j.bmcl.2012.06.060 BindingDB Entry DOI: 10.7270/Q2W0973B
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM106574 (CHEMBL2206404 | US8586617, 7) Show SMILES CC(C)N(Cc1cnc[nH]1)c1ccccc1 Show InChI InChI=1S/C13H17N3/c1-11(2)16(9-12-8-14-10-15-12)13-6-4-3-5-7-13/h3-8,10-11H,9H2,1-2H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 mins				Bioorg Med Chem Lett 22: 5244-8 (2012) Article DOI: 10.1016/j.bmcl.2012.06.060 BindingDB Entry DOI: 10.7270/Q2W0973B
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50227513 (2-(thiophen-2-yl)ethanamine | CHEMBL252803) Show SMILES NCCc1cccs1 Show InChI InChI=1S/C6H9NS/c7-4-3-6-2-1-5-8-6/h1-2,5H,3-4,7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	8.30	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM122294 (US8729113, 1) Show SMILES NC1=N[C@@H](CCOc2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C11H14N2O2/c12-11-13-9(8-15-11)6-7-14-10-4-2-1-3-5-10/h1-5,9H,6-8H2,(H2,12,13)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158488 (CHEMBL3781675) Show SMILES Cc1cc(Cl)ccc1[C@H]1COC(N)=N1 |r,c:13| Show InChI InChI=1S/C10H11ClN2O/c1-6-4-7(11)2-3-8(6)9-5-14-10(12)13-9/h2-4,9H,5H2,1H3,(H2,12,13)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109573 (US8604061, 369) Show SMILES NC1=N[C@H](CO1)c1ccc(Cl)cc1C1CC1 |r,t:1| Show InChI InChI=1S/C12H13ClN2O/c13-8-3-4-9(10(5-8)7-1-2-7)11-6-16-12(14)15-11/h3-5,7,11H,1-2,6H2,(H2,14,15)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM10758 (14C-phenylethylamine | 2-phenylethan-1-amine | CHE...) Show SMILES NCCc1ccccc1 Show InChI InChI=1S/C8H11N/c9-7-6-8-4-2-1-3-5-8/h1-5H,6-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158472 (CHEMBL3780993) Show SMILES NC1=N[C@@]2(CO1)CCc1cccc(Cl)c1C2 |r,t:1| Show InChI InChI=1S/C12H13ClN2O/c13-10-3-1-2-8-4-5-12(6-9(8)10)7-16-11(14)15-12/h1-3H,4-7H2,(H2,14,15)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158471 (CHEMBL3781694) Show SMILES Cc1c(F)cccc1[C@H]1COC(N)=N1 |r,c:13| Show InChI InChI=1S/C10H11FN2O/c1-6-7(3-2-4-8(6)11)9-5-14-10(12)13-9/h2-4,9H,5H2,1H3,(H2,12,13)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109488 (US8604061, 232) Show SMILES NC1=N[C@@H](CCc2cccc(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13ClN2O/c12-9-3-1-2-8(6-9)4-5-10-7-15-11(13)14-10/h1-3,6,10H,4-5,7H2,(H2,13,14)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109524 (US8604061, 292) Show SMILES CC[C@@H](C[C@H]1COC(N)=N1)c1ccccc1 |r,c:8| Show InChI InChI=1S/C13H18N2O/c1-2-10(11-6-4-3-5-7-11)8-12-9-16-13(14)15-12/h3-7,10,12H,2,8-9H2,1H3,(H2,14,15)/t10-,12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109455 (US8604061, 192) Show SMILES NC1=N[C@H](CO1)c1cccc(Cl)c1 |r,t:1| Show InChI InChI=1S/C9H9ClN2O/c10-7-3-1-2-6(4-7)8-5-13-9(11)12-8/h1-4,8H,5H2,(H2,11,12)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM106586 (CHEMBL2206375 | US8586617, 28) Show SMILES CC(C)N(Cc1cnc[nH]1)c1ccc(Cl)cc1 Show InChI InChI=1S/C13H16ClN3/c1-10(2)17(8-12-7-15-9-16-12)13-5-3-11(14)4-6-13/h3-7,9-10H,8H2,1-2H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 mins				Bioorg Med Chem Lett 22: 5244-8 (2012) Article DOI: 10.1016/j.bmcl.2012.06.060 BindingDB Entry DOI: 10.7270/Q2W0973B
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109348 (US8604061, 4) Show SMILES NC1=N[C@H](CO1)c1ccccc1Cl |r,t:1| Show InChI InChI=1S/C9H9ClN2O/c10-7-4-2-1-3-6(7)8-5-13-9(11)12-8/h1-4,8H,5H2,(H2,11,12)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96823 (7-methyl-N-(2-phenylethyl)-8-(3,4,5-trimethoxyphen...) Show SMILES COc1cc(cc(OC)c1OC)C1C(C)C(NCCc2ccccc2)Oc2cc3OCOc3cc12 Show InChI InChI=1S/C28H31NO6/c1-17-26(19-12-24(30-2)27(32-4)25(13-19)31-3)20-14-22-23(34-16-33-22)15-21(20)35-28(17)29-11-10-18-8-6-5-7-9-18/h5-9,12-15,17,26,28-29H,10-11,16H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	23.9	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50581616 (CHEMBL4555465) Show SMILES NCCc1ccsc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109570 (US8604061, 364) Show SMILES CCc1cc(Cl)ccc1[C@H]1COC(N)=N1 |r,c:14| Show InChI InChI=1S/C11H13ClN2O/c1-2-7-5-8(12)3-4-9(7)10-6-15-11(13)14-10/h3-5,10H,2,6H2,1H3,(H2,13,14)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158476 (CHEMBL3781589) Show SMILES CN(C[C@H]1COC(N)=N1)c1cccc(Cl)c1 |r,c:7| Show InChI InChI=1S/C11H14ClN3O/c1-15(6-9-7-16-11(13)14-9)10-4-2-3-8(12)5-10/h2-5,9H,6-7H2,1H3,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158480 (CHEMBL3780421) Show SMILES NC1=N[C@@H](CCCc2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C12H16N2O/c13-12-14-11(9-15-12)8-4-7-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H2,13,14)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109379 (US8604061, 80 (S)) Show SMILES NC1=N[C@@H](CCc2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C11H14N2O/c12-11-13-10(8-14-11)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,12,13)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158477 (CHEMBL3780932) Show SMILES CCN(C[C@H]1COC(N)=N1)c1cccc(Cl)c1 |r,c:8| Show InChI InChI=1S/C12H16ClN3O/c1-2-16(7-10-8-17-12(14)15-10)11-5-3-4-9(13)6-11/h3-6,10H,2,7-8H2,1H3,(H2,14,15)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96768 (4-[(2-phenylethylamino)methylidene]-1-cyclohexa-2,...) Show SMILES Oc1ccc(C=NCCc2ccccc2)cc1 |w:6.6| Show InChI InChI=1S/C15H15NO/c17-15-8-6-14(7-9-15)12-16-11-10-13-4-2-1-3-5-13/h1-9,12,17H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	30.6	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109388 (US8604061, 91) Show SMILES NC1=N[C@H](CO1)c1ccc(Cl)c(Cl)c1 |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-6-2-1-5(3-7(6)11)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96571 (2-methyl-6-(2-phenylethylamino)oxane-3,4,5-triol |...) Show SMILES CC1OC(NCCc2ccccc2)C(O)C(O)C1O Show InChI InChI=1S/C14H21NO4/c1-9-11(16)12(17)13(18)14(19-9)15-8-7-10-5-3-2-4-6-10/h2-6,9,11-18H,7-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	36.6	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM106583 (CHEMBL2206381 | US8586617, 25) Show SMILES COc1cccc(c1)N(Cc1cnc[nH]1)C(C)C Show InChI InChI=1S/C14H19N3O/c1-11(2)17(9-12-8-15-10-16-12)13-5-4-6-14(7-13)18-3/h4-8,10-11H,9H2,1-3H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 mins				Bioorg Med Chem Lett 22: 5244-8 (2012) Article DOI: 10.1016/j.bmcl.2012.06.060 BindingDB Entry DOI: 10.7270/Q2W0973B
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM250359 (US10501411, Example 269 | US11312711, Example 3 | ...) Show SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C18H18F3N3O3/c19-18(20,21)11-27-16-6-3-13(9-23-16)17(25)24-14-4-1-12(2-5-14)15-10-22-7-8-26-15/h1-6,9,15,22H,7-8,10-11H2,(H,24,25)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	37.7	n/a	n/a	n/a	n/a
TBA					Assay Description For the construction of expression plasmids the coding sequences of human TAAR1 were amplified from genomic DNA essentially as described by Lindemann...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q243FD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM250359 (US10501411, Example 269 | US11312711, Example 3 | ...) Show SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C18H18F3N3O3/c19-18(20,21)11-27-16-6-3-13(9-23-16)17(25)24-14-4-1-12(2-5-14)15-10-22-7-8-26-15/h1-6,9,15,22H,7-8,10-11H2,(H,24,25)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	37.7	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For the construction of expression plasmids the coding sequences of human TAAR 1 were amplified from genomic DNA essentially as described by Lindeman...				US Patent US10508107 (2019) BindingDB Entry DOI: 10.7270/Q2RR21M8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50581604 (SEP-363856 | SEP-856 | Sep-363856 | ULOTARONT | Ul...) Show SMILES CNC[C@@H]1OCCc2ccsc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM106608 (CHEMBL2206388 | US8586617, 113) Show SMILES COc1cccc(n1)N(Cc1cnc[nH]1)C(C)C Show InChI InChI=1S/C13H18N4O/c1-10(2)17(8-11-7-14-9-15-11)12-5-4-6-13(16-12)18-3/h4-7,9-10H,8H2,1-3H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 mins				Bioorg Med Chem Lett 22: 5244-8 (2012) Article DOI: 10.1016/j.bmcl.2012.06.060 BindingDB Entry DOI: 10.7270/Q2W0973B
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM109487 (US8604061, 231) Show SMILES C[C@@]1(COC(N)=N1)c1ccc(Br)cc1 |r,c:5| Show InChI InChI=1S/C10H11BrN2O/c1-10(6-14-9(12)13-10)7-2-4-8(11)5-3-7/h2-5H,6H2,1H3,(H2,12,13)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96655 ((6E)-4-chloranyl-6-[(2-phenylethylamino)methyliden...) Show SMILES Oc1ccc(Cl)cc1C=NCCc1ccccc1 |w:9.10| Show InChI InChI=1S/C15H14ClNO/c16-14-6-7-15(18)13(10-14)11-17-9-8-12-4-2-1-3-5-12/h1-7,10-11,18H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	42.5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50262799 (2-(2,6-dichlorophenyl)ethylamine | CHEMBL510649) Show SMILES NCCc1c(Cl)cccc1Cl Show InChI InChI=1S/C8H9Cl2N/c9-7-2-1-3-8(10)6(7)4-5-11/h1-3H,4-5,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...				Bioorg Med Chem 16: 7415-23 (2008) Article DOI: 10.1016/j.bmc.2008.06.009 BindingDB Entry DOI: 10.7270/Q2DR2V92
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50581606 (CHEMBL5094122) Show SMILES CNCC1OCCc2ccsc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50262753 (2-(2-bromopheneyl)ethylamine | CHEMBL447753) Show SMILES NCCc1ccccc1Br Show InChI InChI=1S/C8H10BrN/c9-8-4-2-1-3-7(8)5-6-10/h1-4H,5-6,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...				Bioorg Med Chem 16: 7415-23 (2008) Article DOI: 10.1016/j.bmc.2008.06.009 BindingDB Entry DOI: 10.7270/Q2DR2V92
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM422652 (5-Ethyl-4-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]...) Show SMILES CCc1[nH]nc(C(=O)Nc2ccc(cc2)[C@H]2CNCCO2)c1C |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	n/a	58.5	n/a	n/a	n/a	n/a
TBA					Assay Description For the construction of expression plasmids the coding sequences of human TAAR1 were amplified from genomic DNA essentially as described by Lindemann...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q243FD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM422652 (5-Ethyl-4-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]...) Show SMILES CCc1[nH]nc(C(=O)Nc2ccc(cc2)[C@H]2CNCCO2)c1C |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	n/a	n/a	58.5	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For the construction of expression plasmids the coding sequences of human TAAR 1 were amplified from genomic DNA essentially as described by Lindeman...				US Patent US10508107 (2019) BindingDB Entry DOI: 10.7270/Q2RR21M8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158431 (CHEMBL3779993) Show SMILES CCN(C[C@H]1COC(N)=N1)c1ccccc1 |r,c:8| Show InChI InChI=1S/C12H17N3O/c1-2-15(11-6-4-3-5-7-11)8-10-9-16-12(13)14-10/h3-7,10H,2,8-9H2,1H3,(H2,13,14)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM250298 (US10501411, Example 208 | US11312711, Example 12 |...) Show SMILES Clc1ccc(cn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C16H16ClN3O2/c17-15-6-3-12(9-19-15)16(21)20-13-4-1-11(2-5-13)14-10-18-7-8-22-14/h1-6,9,14,18H,7-8,10H2,(H,20,21)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	61.9	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For the construction of expression plasmids the coding sequences of human TAAR 1 were amplified from genomic DNA essentially as described by Lindeman...				US Patent US10508107 (2019) BindingDB Entry DOI: 10.7270/Q2RR21M8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM250298 (US10501411, Example 208 | US11312711, Example 12 |...) Show SMILES Clc1ccc(cn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C16H16ClN3O2/c17-15-6-3-12(9-19-15)16(21)20-13-4-1-11(2-5-13)14-10-18-7-8-22-14/h1-6,9,14,18H,7-8,10H2,(H,20,21)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	61.9	n/a	n/a	n/a	n/a
TBA					Assay Description For the construction of expression plasmids the coding sequences of human TAAR1 were amplified from genomic DNA essentially as described by Lindemann...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q243FD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM96596 (2-(2-Phenylamino-quinazolin-4-ylamino)-ethanol | 2...) Show SMILES OCCNc1nc(Nc2ccccc2)nc2ccccc12 Show InChI InChI=1S/C16H16N4O/c21-11-10-17-15-13-8-4-5-9-14(13)19-16(20-15)18-12-6-2-1-3-7-12/h1-9,21H,10-11H2,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	63.4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50581613 (CHEMBL5077361) Show SMILES NCC1OCCCc2ccsc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00527 BindingDB Entry DOI: 10.7270/Q25X2DSH
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50241031 (2-(2-fluorophenyl)ethanamine | 2-(2-fluorophenyl)e...) Show SMILES NCCc1ccccc1F Show InChI InChI=1S/C8H10FN/c9-8-4-2-1-3-7(8)5-6-10/h1-4H,5-6,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...				Bioorg Med Chem 16: 7415-23 (2008) Article DOI: 10.1016/j.bmc.2008.06.009 BindingDB Entry DOI: 10.7270/Q2DR2V92
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM473797 ((4S)-4-(3-fluoro-2-methylphenyl)-N-[(4S)-4-(3-fluo...) Show SMILES Cc1c(F)cccc1[C@H]1COC(NC2=N[C@H](CO2)c2cccc(F)c2C)=N1 |r,c:28,t:14| Show InChI InChI=1S/C20H19F2N3O2/c1-11-13(5-3-7-15(11)21)17-9-26-19(23-17)25-20-24-18(10-27-20)14-6-4-8-16(22)12(14)2/h3-8,17-18H,9-10H2,1-2H3,(H,23,24,25)/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	65.5	n/a	n/a	n/a	n/a
PURDUE PHARMA L.P. US Patent					Assay Description EC50 (the effective concentration of an agonist that produces half of the maximal effect) and Emax (the maximal cAMP level generated by the biding of...				US Patent US10858326 (2020) BindingDB Entry DOI: 10.7270/Q2R78J9J
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM422671 (US10508107, Example 5 | US11312711, Example 5) Show SMILES Clc1cc(ccn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C16H16ClN3O2/c17-15-9-12(5-6-19-15)16(21)20-13-3-1-11(2-4-13)14-10-18-7-8-22-14/h1-6,9,14,18H,7-8,10H2,(H,20,21)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	65.6	n/a	n/a	n/a	n/a
TBA					Assay Description For the construction of expression plasmids the coding sequences of human TAAR1 were amplified from genomic DNA essentially as described by Lindemann...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Q243FD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM422671 (US10508107, Example 5 | US11312711, Example 5) Show SMILES Clc1cc(ccn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C16H16ClN3O2/c17-15-9-12(5-6-19-15)16(21)20-13-3-1-11(2-4-13)14-10-18-7-8-22-14/h1-6,9,14,18H,7-8,10H2,(H,20,21)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	65.6	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For the construction of expression plasmids the coding sequences of human TAAR 1 were amplified from genomic DNA essentially as described by Lindeman...				US Patent US10508107 (2019) BindingDB Entry DOI: 10.7270/Q2RR21M8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158487 (CHEMBL3781461) Show SMILES Cc1ccccc1[C@H]1COC(N)=N1 |r,c:12| Show InChI InChI=1S/C10H12N2O/c1-7-4-2-3-5-8(7)9-6-13-10(11)12-9/h2-5,9H,6H2,1H3,(H2,11,12)/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM50158481 (CHEMBL3781899) Show SMILES NC1=N[C@H](CO1)c1ccccc1 |r,t:1| Show InChI InChI=1S/C9H10N2O/c10-9-11-8(6-12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H2,10,11)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Roche Innovation Center Basel Curated by ChEMBL					Assay Description Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer				ACS Med Chem Lett 7: 192-7 (2016) Article DOI: 10.1021/acsmedchemlett.5b00449 BindingDB Entry DOI: 10.7270/Q2NP2687
					More data for this Ligand-Target Pair

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