Compile Data Set for Download or QSAR

Found 13 hits of ec50 for UniProtKB: Q99759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54961 (6-(3-ethoxyphenyl)-3-thiophen-2-yl-[1,2,4]triazolo...) Show SMILES CCOc1cccc(c1)-c1nn2c(nnc2s1)-c1cccs1 Show InChI InChI=1S/C15H12N4OS2/c1-2-20-11-6-3-5-10(9-11)14-18-19-13(12-7-4-8-21-12)16-17-15(19)22-14/h3-9H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM38325 (6-(3,4-dimethoxyphenyl)-3-(2-pyridinyl)-[1,2,4]tri...) Show SMILES COc1ccc(cc1OC)-c1nn2c(nnc2s1)-c1ccccn1 Show InChI InChI=1S/C16H13N5O2S/c1-22-12-7-6-10(9-13(12)23-2)15-20-21-14(18-19-16(21)24-15)11-5-3-4-8-17-11/h3-9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54951 ((6Z)-3-(2-furanyl)-6-(2-pyrrolylidene)-5H-[1,2,4]t...) Show SMILES c1c[nH]c(c1)-c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C11H7N5OS/c1-3-7(12-5-1)10-15-16-9(8-4-2-6-17-8)13-14-11(16)18-10/h1-6,12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54952 (6-cycloheptyl-3-(2-furanyl)-[1,2,4]triazolo[3,4-b]...) Show SMILES C1CCCC(CC1)c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C14H16N4OS/c1-2-4-7-10(6-3-1)13-17-18-12(11-8-5-9-19-11)15-16-14(18)20-13/h5,8-10H,1-4,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54953 (3-(2-furanyl)-6-(2-methoxy-4-nitrophenyl)-[1,2,4]t...) Show SMILES COc1cc(ccc1-c1nn2c(nnc2s1)-c1ccco1)[N+]([O-])=O Show InChI InChI=1S/C14H9N5O4S/c1-22-11-7-8(19(20)21)4-5-9(11)13-17-18-12(10-3-2-6-23-10)15-16-14(18)24-13/h2-7H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54954 (6-cyclohexyl-3-(2-pyridinyl)-[1,2,4]triazolo[3,4-b...) Show SMILES C1CCC(CC1)c1nn2c(nnc2s1)-c1ccccn1 Show InChI InChI=1S/C14H15N5S/c1-2-6-10(7-3-1)13-18-19-12(16-17-14(19)20-13)11-8-4-5-9-15-11/h4-5,8-10H,1-3,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54956 (6-cycloheptyl-3-(2-pyridinyl)-[1,2,4]triazolo[3,4-...) Show SMILES C1CCCC(CC1)c1nn2c(nnc2s1)-c1ccccn1 Show InChI InChI=1S/C15H17N5S/c1-2-4-8-11(7-3-1)14-19-20-13(17-18-15(20)21-14)12-9-5-6-10-16-12/h5-6,9-11H,1-4,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54957 (6-(2-methoxy-4-nitro-phenyl)-3-(2-pyridyl)-[1,2,4]...) Show SMILES COc1cc(ccc1-c1nn2c(nnc2s1)-c1ccccn1)[N+]([O-])=O Show InChI InChI=1S/C15H10N6O3S/c1-24-12-8-9(21(22)23)5-6-10(12)14-19-20-13(17-18-15(20)25-14)11-4-2-3-7-16-11/h2-8H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54958 (6-(3-methoxyphenyl)-3-(2-pyridinyl)-[1,2,4]triazol...) Show SMILES COc1cccc(c1)-c1nn2c(nnc2s1)-c1ccccn1 Show InChI InChI=1S/C15H11N5OS/c1-21-11-6-4-5-10(9-11)14-19-20-13(17-18-15(20)22-14)12-7-2-3-8-16-12/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54959 (3-(2-furyl)-6-m-phenetyl-[1,2,4]triazolo[3,4-b][1,...) Show SMILES CCOc1cccc(c1)-c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C15H12N4O2S/c1-2-20-11-6-3-5-10(9-11)14-18-19-13(12-7-4-8-21-12)16-17-15(19)22-14/h3-9H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54960 (3-(4-pyridyl)-6-(2-thenyl)-[1,2,4]triazolo[3,4-b][...) Show SMILES C(c1cccs1)c1nn2c(nnc2s1)-c1ccncc1 Show InChI InChI=1S/C13H9N5S2/c1-2-10(19-7-1)8-11-17-18-12(15-16-13(18)20-11)9-3-5-14-6-4-9/h1-7H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54950 (6-cyclohexyl-3-(2-furanyl)-[1,2,4]triazolo[3,4-b][...) Show SMILES C1CCC(CC1)c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C13H14N4OS/c1-2-5-9(6-3-1)12-16-17-11(10-7-4-8-18-10)14-15-13(17)19-12/h4,7-9H,1-3,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 3 (Homo sapiens (Human))	BDBM54955 ((6Z)-3-(2-pyridinyl)-6-(2-pyrrolylidene)-5H-[1,2,4...) Show SMILES c1c[nH]c(c1)-c1nn2c(nnc2s1)-c1ccccn1 Show InChI InChI=1S/C12H8N6S/c1-2-6-13-8(4-1)10-15-16-12-18(10)17-11(19-12)9-5-3-7-14-9/h1-7,14H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair