Compile Data Set for Download or QSAR

Found 15 hits of ic50 for UniProtKB: P03373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273882 (2-[3-chloro-3-phenylprop-2-enylidene]hydrazinecarb...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]=[#6](Cl)-c1ccccc1 |w:6.5,4.3| Show InChI InChI=1S/C10H11ClN4/c11-9(6-7-14-15-10(12)13)8-4-2-1-3-5-8/h1-7H,(H4,12,13,15)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273849 (1-Chloro-5,7-dimethyl-3,4-dihydronaphthalene-2-car...) Show SMILES [#6]-c1cc(-[#6])c2-[#6]-[#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c2c1 |w:9.8,t:14| Show InChI InChI=1S/C14H17ClN4/c1-8-5-9(2)11-4-3-10(7-18-19-14(16)17)13(15)12(11)6-8/h5-7H,3-4H2,1-2H3,(H4,16,17,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273851 (2-[(3-chloro-1H-inden-2-yl)methylene]hydrazinecarb...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](Cl)-c2ccccc2-[#6]-1 |w:5.5,c:6| Show InChI InChI=1S/C11H11ClN4/c12-10-8(6-15-16-11(13)14)5-7-3-1-2-4-9(7)10/h1-4,6H,5H2,(H4,13,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50253469 (1-Chloro-3,4-dihydronaphthalene-2-carboxaldehyde g...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](Cl)-c2ccccc2-[#6]-[#6]-1 |w:5.5,c:6| Show InChI InChI=1S/C12H13ClN4/c13-11-9(7-16-17-12(14)15)6-5-8-3-1-2-4-10(8)11/h1-4,7H,5-6H2,(H4,14,15,17)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273883 (CHEMBL460174 | beta-Chloro-alpha-methylcinnamaldeh...) Show SMILES [#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c1ccccc1 |w:2.1,1.0| Show InChI InChI=1S/C11H13ClN4/c1-8(7-15-16-11(13)14)10(12)9-5-3-2-4-6-9/h2-7H,1H3,(H4,13,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273850 (1-Chloro-3-dihydro-4-methylnaphthalene-2-carboxald...) Show SMILES [#6]-[#6]-1-[#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c2ccccc-12 |w:4.3,t:9| Show InChI InChI=1S/C13H15ClN4/c1-8-6-9(7-17-18-13(15)16)12(14)11-5-3-2-4-10(8)11/h2-5,7-8H,6H2,1H3,(H4,15,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273848 (1-Chloro-6-methoxy-3,4-dihydronaphthalene-2-carbox...) Show SMILES [#6]-[#8]-c1ccc2-[#6](Cl)=[#6](-[#6]-[#6]-c2c1)-[#6]=[#7]\[#7]=[#6](\[#7])-[#7] |w:13.14,c:7| Show InChI InChI=1S/C13H15ClN4O/c1-19-10-4-5-11-8(6-10)2-3-9(12(11)14)7-17-18-13(15)16/h4-7H,2-3H2,1H3,(H4,15,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273854 (1-Methoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...) Show SMILES [#6]-[#8]-[#6]-1=[#6](-[#6]-[#6]-c2ccccc-12)-[#6]=[#7]\[#7]=[#6](\[#7])-[#7] |w:12.13,t:2| Show InChI InChI=1S/C13H16N4O/c1-18-12-10(8-16-17-13(14)15)7-6-9-4-2-3-5-11(9)12/h2-5,8H,6-7H2,1H3,(H4,14,15,17)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273852 (9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](Cl)-c2ccccc2-[#6]-[#6]-[#6]-1 |w:5.5,c:6| Show InChI InChI=1S/C13H15ClN4/c14-12-10(8-17-18-13(15)16)6-3-5-9-4-1-2-7-11(9)12/h1-2,4,7-8H,3,5-6H2,(H4,15,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273880 (1-Phenoxy-3,4-dihydronaphthalene-2-carboxaldehyde ...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](-[#8]-c2ccccc2)-c2ccccc2-[#6]-[#6]-1 |w:5.5,c:6| Show InChI InChI=1S/C18H18N4O/c19-18(20)22-21-12-14-11-10-13-6-4-5-9-16(13)17(14)23-15-7-2-1-3-8-15/h1-9,12H,10-11H2,(H4,19,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273847 (1-Chloro-7-methoxy-3,4-dihydronaphthalene-2-carbox...) Show SMILES [#6]-[#8]-c1ccc2-[#6]-[#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c2c1 |w:9.8,t:14| Show InChI InChI=1S/C13H15ClN4O/c1-19-10-5-4-8-2-3-9(7-17-18-13(15)16)12(14)11(8)6-10/h4-7H,2-3H2,1H3,(H4,15,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50240439 (2-(1-Naphthalenylmethylene) hydrazinecarboximidami...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1cccc2ccccc12 |w:5.5| Show InChI InChI=1S/C12H12N4/c13-12(14)16-15-8-10-6-3-5-9-4-1-2-7-11(9)10/h1-8H,(H4,13,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50240438 (2-(2-Naphthalenylmethylene)hydrazinecarboximidamid...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1ccc2ccccc2c1 |w:5.5| Show InChI InChI=1S/C12H12N4/c13-12(14)16-15-8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H,(H4,13,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273853 (1-Bromo-3,4-dihydronaphthalene-2-carboxaldehyde gu...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](Br)-c2ccccc2-[#6]-[#6]-1 |w:5.5,c:6| Show InChI InChI=1S/C12H13BrN4/c13-11-9(7-16-17-12(14)15)6-5-8-3-1-2-4-10(8)11/h1-4,7H,5-6H2,(H4,14,15,17)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair
Gag polyprotein (Avian erythroblastosis virus (strain ES4))	BDBM50273881 (1-(1,1,1,-Trifluoromethyl)-3,4-dihydronaphthalene-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](-c2ccccc2-[#6]-[#6]-1)C(F)(F)F |w:5.5,t:6| Show InChI InChI=1S/C13H13F3N4/c14-13(15,16)11-9(7-19-20-12(17)18)6-5-8-3-1-2-4-10(8)11/h1-4,7H,5-6H2,(H4,17,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Urbana-Champaign Curated by ChEMBL					Assay Description Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...				Bioorg Med Chem 16: 10075-84 (2008) Article DOI: 10.1016/j.bmc.2008.10.007 BindingDB Entry DOI: 10.7270/Q28915Q2
					More data for this Ligand-Target Pair