Compile Data Set for Download or QSAR

Found 52 hits of ic50 for UniProtKB: P11168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152749 (CHEMBL3781913) Show SMILES COc1ccccc1N1CCCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-30-21-11-6-5-10-20(21)27-12-7-13-28(15-14-27)22-19-16-26-29(23(19)25-17-24-22)18-8-3-2-4-9-18/h2-6,8-11,16-17H,7,12-15H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155715 (CHEMBL3781149) Show SMILES Oc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H28Br2ClN5O/c27-19-12-18-6-5-17-13-20(29)14-21(28)23(17)25(24(18)32-15-19)34-10-2-1-4-22(34)26(35)31-7-3-9-33-11-8-30-16-33/h8,11-16,22,25H,1-7,9-10H2,(H,31,35)/t22-,25?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155656 (CHEMBL3781331) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C(N)=O Show InChI InChI=1S/C23H23N7O2/c1-32-20-8-7-16(21(24)31)13-19(20)28-9-11-29(12-10-28)22-18-14-27-30(23(18)26-15-25-22)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3,(H2,24,31)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155680 (CHEMBL3780717) Show SMILES N#Cc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H19N7/c23-14-17-5-4-8-19(13-17)27-9-11-28(12-10-27)21-20-15-26-29(22(20)25-16-24-21)18-6-2-1-3-7-18/h1-8,13,15-16H,9-12H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155585 (CHEMBL3780372) Show SMILES COc1ccncc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H21N7O/c1-29-19-7-8-22-14-18(19)26-9-11-27(12-10-26)20-17-13-25-28(21(17)24-15-23-20)16-5-3-2-4-6-16/h2-8,13-15H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152765 (CHEMBL3780756) Show SMILES COc1ccccc1N1CCN(CC1)c1ccnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H23N5O/c1-29-22-10-6-5-9-21(22)27-15-13-26(14-16-27)20-11-12-24-23-19(20)17-25-28(23)18-7-3-2-4-8-18/h2-12,17H,13-16H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155753 (CHEMBL3780470) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cc(F)ccc1OC Show InChI InChI=1S/C23H23FN6O2/c1-31-20-6-4-3-5-18(20)28-9-11-29(12-10-28)22-17-14-27-30(23(17)26-15-25-22)19-13-16(24)7-8-21(19)32-2/h3-8,13-15H,9-12H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155679 (CHEMBL3780772) Show SMILES COc1cccc(c1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-18-7-5-6-17(14-18)29-23-19(15-26-29)22(24-16-25-23)28-12-10-27(11-13-28)20-8-3-4-9-21(20)31-2/h3-9,14-16H,10-13H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155583 (CHEMBL3781835) Show SMILES COc1cccnc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H21N7O/c1-29-18-8-5-9-22-21(18)27-12-10-26(11-13-27)19-17-14-25-28(20(17)24-15-23-19)16-6-3-2-4-7-16/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152826 (CHEMBL3781347) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1C Show InChI InChI=1S/C23H24N6O/c1-17-7-3-4-8-19(17)29-23-18(15-26-29)22(24-16-25-23)28-13-11-27(12-14-28)20-9-5-6-10-21(20)30-2/h3-10,15-16H,11-14H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152824 (CHEMBL3781548) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1F Show InChI InChI=1S/C22H21FN6O/c1-30-20-9-5-4-8-19(20)27-10-12-28(13-11-27)21-16-14-26-29(22(16)25-15-24-21)18-7-3-2-6-17(18)23/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155674 (CHEMBL3780459) Show SMILES Fc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H19FN6/c22-18-8-4-5-9-19(18)26-10-12-27(13-11-26)20-17-14-25-28(21(17)24-15-23-20)16-6-2-1-3-7-16/h1-9,14-15H,10-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152825 (CHEMBL3780235) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-20-9-5-3-7-18(20)27-11-13-28(14-12-27)22-17-15-26-29(23(17)25-16-24-22)19-8-4-6-10-21(19)31-2/h3-10,15-16H,11-14H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155591 (CHEMBL3781654) Show SMILES COc1cccc(F)c1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-19-9-5-8-18(23)20(19)27-10-12-28(13-11-27)21-17-14-26-29(22(17)25-15-24-21)16-6-3-2-4-7-16/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155682 (CHEMBL3781994) Show SMILES Fc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H19FN6/c22-16-5-4-8-18(13-16)26-9-11-27(12-10-26)20-19-14-25-28(21(19)24-15-23-20)17-6-2-1-3-7-17/h1-8,13-15H,9-12H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155587 (CHEMBL3780764) Show SMILES COc1ncccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H21N7O/c1-29-21-18(8-5-9-22-21)26-10-12-27(13-11-26)19-17-14-25-28(20(17)24-15-23-19)16-6-3-2-4-7-16/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152743 (CHEMBL3781308) Show SMILES COc1ccccc1N1CCN(CC1C)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-17-15-27(12-13-28(17)20-10-6-7-11-21(20)30-2)22-19-14-26-29(23(19)25-16-24-22)18-8-4-3-5-9-18/h3-11,14,16-17H,12-13,15H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155681 (CHEMBL3781827) Show SMILES COc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6O/c1-29-19-9-5-8-18(14-19)26-10-12-27(13-11-26)21-20-15-25-28(22(20)24-16-23-21)17-6-3-2-4-7-17/h2-9,14-16H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155672 (CHEMBL3781183) Show SMILES COc1cc(ccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-13-17(14-24)7-8-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155752 (CHEMBL3780527) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C1CCCC1 Show InChI InChI=1S/C21H26N6O/c1-28-19-9-5-4-8-18(19)25-10-12-26(13-11-25)20-17-14-24-27(16-6-2-3-7-16)21(17)23-15-22-20/h4-5,8-9,14-16H,2-3,6-7,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155754 (CHEMBL3780729) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C(C)c1ccccc1 Show InChI InChI=1S/C24H26N6O/c1-18(19-8-4-3-5-9-19)30-24-20(16-27-30)23(25-17-26-24)29-14-12-28(13-15-29)21-10-6-7-11-22(21)31-2/h3-11,16-18H,12-15H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152744 (CHEMBL3781633) Show SMILES COc1ccccc1N1CCN(C(C)C1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-17-15-27(20-10-6-7-11-21(20)30-2)12-13-28(17)22-19-14-26-29(23(19)25-16-24-22)18-8-4-3-5-9-18/h3-11,14,16-17H,12-13,15H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155749 (CHEMBL3781625) Show SMILES COc1ccc(cc1)-n1ncc2c(ncnc12)N1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-18-9-7-17(8-10-18)29-23-19(15-26-29)22(24-16-25-23)28-13-11-27(12-14-28)20-5-3-4-6-21(20)31-2/h3-10,15-16H,11-14H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152774 (CHEMBL3781384) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(nnc12)-c1ccccc1 Show InChI InChI=1S/C168H254N44O52/c1-17-89(10)137(165(260)188-93(14)144(239)197-118(72-99-75-180-104-38-25-24-37-102(99)104)155(250)199-114(68-86(4)5)156(251)208-135(87(6)7)163(258)196-106(40-26-29-58-169)146(241)181-77-125(221)189-107(42-32-61-179-168(174)175)150(245)191-105(140(173)235)39-28-31-60-177-128(224)83-264-66-65-263-64-62-178-124(220)57-63-212-129(225)52-53-130(212)226)210-157(252)116(69-96-33-20-18-21-34-96)200-152(247)112(50-56-133(231)232)195-151(246)108(41-27-30-59-170)192-142(237)91(12)185-141(236)90(11)187-149(244)111(47-51-123(172)219)190-126(222)78-182-148(243)110(49-55-132(229)230)194-153(248)113(67-85(2)3)198-154(249)115(71-98-43-45-101(218)46-44-98)201-160(255)120(80-213)204-162(257)122(82-215)205-164(259)136(88(8)9)209-159(254)119(74-134(233)234)202-161(256)121(81-214)206-167(262)139(95(16)217)211-158(253)117(70-97-35-22-19-23-36-97)203-166(261)138(94(15)216)207-127(223)79-183-147(242)109(48-54-131(227)228)193-143(238)92(13)186-145(240)103(171)73-100-76-176-84-184-100/h18-25,33-38,43-46,52-53,75-76,84-95,103,105-122,135-139,180,213-218H,17,26-32,39-42,47-51,54-74,77-83,169-171H2,1-16H3,(H2,172,219)(H2,173,235)(H,176,184)(H,177,224)(H,178,220)(H,181,241)(H,182,243)(H,183,242)(H,185,236)(H,186,240)(H,187,244)(H,188,260)(H,189,221)(H,190,222)(H,191,245)(H,192,237)(H,193,238)(H,194,248)(H,195,246)(H,196,258)(H,197,239)(H,198,249)(H,199,250)(H,200,247)(H,201,255)(H,202,256)(H,203,261)(H,204,257)(H,205,259)(H,206,262)(H,207,223)(H,208,251)(H,209,254)(H,210,252)(H,211,253)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H4,174,175,179)/t89-,90-,91-,92-,93-,94+,95+,103-,105?,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,135-,136-,137-,138-,139-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152776 (CHEMBL3780785) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(cnc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6O/c1-29-19-10-6-5-9-18(19)26-11-13-27(14-12-26)21-20-22(24-15-23-21)28(16-25-20)17-7-3-2-4-8-17/h2-10,15-16H,11-14H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155757 (CHEMBL3780845) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccncc1 Show InChI InChI=1S/C21H21N7O/c1-29-19-5-3-2-4-18(19)26-10-12-27(13-11-26)20-17-14-25-28(21(17)24-15-23-20)16-6-8-22-9-7-16/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152766 (CHEMBL3781757) Show SMILES COc1ccccc1N1CCN(CC1)c1nccc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H23N5O/c1-29-22-10-6-5-9-21(22)26-13-15-27(16-14-26)23-19-17-25-28(20(19)11-12-24-23)18-7-3-2-4-8-18/h2-12,17H,13-16H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155684 (CHEMBL3781094) Show SMILES N#Cc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H19N7/c23-14-17-6-4-5-9-20(17)27-10-12-28(13-11-27)21-19-15-26-29(22(19)25-16-24-21)18-7-2-1-3-8-18/h1-9,15-16H,10-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155756 (CHEMBL3781797) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccnc1 Show InChI InChI=1S/C21H21N7O/c1-29-19-7-3-2-6-18(19)26-9-11-27(12-10-26)20-17-14-25-28(21(17)24-15-23-20)16-5-4-8-22-13-16/h2-8,13-15H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155748 (CHEMBL3781535) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ncccc1F Show InChI InChI=1S/C21H20FN7O/c1-30-18-7-3-2-6-17(18)27-9-11-28(12-10-27)19-15-13-26-29(20(15)25-14-24-19)21-16(22)5-4-8-23-21/h2-8,13-14H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155755 (CHEMBL3780349) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccn1 Show InChI InChI=1S/C21H21N7O/c1-29-18-7-3-2-6-17(18)26-10-12-27(13-11-26)20-16-14-25-28(21(16)24-15-23-20)19-8-4-5-9-22-19/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155678 (CHEMBL3780534) Show SMILES COc1ccc(cc1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6O/c1-29-19-9-7-17(8-10-19)26-11-13-27(14-12-26)21-20-15-25-28(22(20)24-16-23-21)18-5-3-2-4-6-18/h2-10,15-16H,11-14H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155747 (CHEMBL3781194) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-5-3-2-4-20(21)28-10-12-29(13-11-28)22-19-15-27-30(23(19)26-16-25-22)18-8-6-17(14-24)7-9-18/h2-9,15-16H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155751 (CHEMBL3780460) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C22H20F2N6O/c1-31-20-5-3-2-4-19(20)28-6-8-29(9-7-28)21-18-13-27-30(22(18)26-14-25-21)17-11-15(23)10-16(24)12-17/h2-5,10-14H,6-9H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155714 (CHEMBL3781157) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H25Br2ClN4O/c27-19-10-18-7-6-17-11-20(29)12-21(28)23(17)25(24(18)31-15-19)33-9-2-1-5-22(33)26(34)32-14-16-4-3-8-30-13-16/h3-4,8,10-13,15,22,25H,1-2,5-7,9,14H2,(H,32,34)/t22-,25?/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155685 (CHEMBL3780403) Show SMILES FC(F)(F)Oc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H19F3N6O/c23-22(24,25)32-19-9-5-4-8-18(19)29-10-12-30(13-11-29)20-17-14-28-31(21(17)27-15-26-20)16-6-2-1-3-7-16/h1-9,14-15H,10-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155683 (CHEMBL3781573) Show SMILES FC(F)(F)c1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H19F3N6/c23-22(24,25)18-8-4-5-9-19(18)29-10-12-30(13-11-29)20-17-14-28-31(21(17)27-15-26-20)16-6-2-1-3-7-16/h1-9,14-15H,10-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155584 (CHEMBL1551510) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccc(C)cc1 Show InChI InChI=1S/C23H24N6O/c1-17-7-9-18(10-8-17)29-23-19(15-26-29)22(24-16-25-23)28-13-11-27(12-14-28)20-5-3-4-6-21(20)30-2/h3-10,15-16H,11-14H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155676 (CHEMBL3781161) Show SMILES COc1c(F)cccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-18(23)8-5-9-19(20)27-10-12-28(13-11-27)21-17-14-26-29(22(17)25-15-24-21)16-6-3-2-4-7-16/h2-9,14-15H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155675 (CHEMBL3781447) Show SMILES COc1c(cccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-17(14-24)6-5-9-20(21)28-10-12-29(13-11-28)22-19-15-27-30(23(19)26-16-25-22)18-7-3-2-4-8-18/h2-9,15-16H,10-13H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155673 (CHEMBL3780972) Show SMILES COc1cc(F)ccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-13-16(23)7-8-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155670 (CHEMBL3780144) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-7-17(14-24)13-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155671 (CHEMBL3780239) Show SMILES COc1ccc(F)cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-8-7-16(23)13-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50155582 (CHEMBL3781086) Show SMILES OC1CCCCC1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H26N6O/c28-19-9-5-4-8-18(19)25-10-12-26(13-11-25)20-17-14-24-27(21(17)23-15-22-20)16-6-2-1-3-7-16/h1-3,6-7,14-15,18-19,28H,4-5,8-13H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152740 (CHEMBL3781668) Show SMILES COc1ccccc1C1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H23N5O/c1-29-21-10-6-5-9-19(21)17-11-13-27(14-12-17)22-20-15-26-28(23(20)25-16-24-22)18-7-3-2-4-8-18/h2-10,15-17H,11-14H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152746 (CHEMBL3780119) Show SMILES [H][C@@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@@]([H])(CN1c1ccccc1OC)C2 |r| Show InChI InChI=1S/C23H22N6O/c1-30-21-10-6-5-9-20(21)27-13-18-11-17(27)14-28(18)22-19-12-26-29(23(19)25-15-24-22)16-7-3-2-4-8-16/h2-10,12,15,17-18H,11,13-14H2,1H3/t17-,18-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152745 (CHEMBL3780730) Show SMILES [H][C@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@]([H])(CN1c1ccccc1OC)C2 |r| Show InChI InChI=1S/C23H22N6O/c1-30-21-10-6-5-9-20(21)27-13-18-11-17(27)14-28(18)22-19-12-26-29(23(19)25-15-24-22)16-7-3-2-4-8-16/h2-10,12,15,17-18H,11,13-14H2,1H3/t17-,18-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152771 (CHEMBL3781893) Show SMILES COc1ccccc1N1CCN(CC1)c1nnnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C168H254N44O52/c1-17-89(10)137(165(260)188-93(14)144(239)197-118(72-99-75-180-104-38-25-24-37-102(99)104)155(250)199-114(68-86(4)5)156(251)208-135(87(6)7)163(258)196-106(40-26-29-58-169)146(241)181-77-125(221)189-107(42-32-61-179-168(174)175)150(245)191-105(140(173)235)39-28-31-60-177-128(224)83-264-66-65-263-64-62-178-124(220)57-63-212-129(225)52-53-130(212)226)210-157(252)116(69-96-33-20-18-21-34-96)200-152(247)112(50-56-133(231)232)195-151(246)108(41-27-30-59-170)192-142(237)91(12)185-141(236)90(11)187-149(244)111(47-51-123(172)219)190-126(222)78-182-148(243)110(49-55-132(229)230)194-153(248)113(67-85(2)3)198-154(249)115(71-98-43-45-101(218)46-44-98)201-160(255)120(80-213)204-162(257)122(82-215)205-164(259)136(88(8)9)209-159(254)119(74-134(233)234)202-161(256)121(81-214)206-167(262)139(95(16)217)211-158(253)117(70-97-35-22-19-23-36-97)203-166(261)138(94(15)216)207-127(223)79-183-147(242)109(48-54-131(227)228)193-143(238)92(13)186-145(240)103(171)73-100-76-176-84-184-100/h18-25,33-38,43-46,52-53,75-76,84-95,103,105-122,135-139,180,213-218H,17,26-32,39-42,47-51,54-74,77-83,169-171H2,1-16H3,(H2,172,219)(H2,173,235)(H,176,184)(H,177,224)(H,178,220)(H,181,241)(H,182,243)(H,183,242)(H,185,236)(H,186,240)(H,187,244)(H,188,260)(H,189,221)(H,190,222)(H,191,245)(H,192,237)(H,193,238)(H,194,248)(H,195,246)(H,196,258)(H,197,239)(H,198,249)(H,199,250)(H,200,247)(H,201,255)(H,202,256)(H,203,261)(H,204,257)(H,205,259)(H,206,262)(H,207,223)(H,208,251)(H,209,254)(H,210,252)(H,211,253)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H4,174,175,179)/t89-,90-,91-,92+,93-,94+,95+,103-,105?,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,135-,136-,137-,138-,139-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152823 (CHEMBL3780054) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(-c3ccccc3)c(=O)[nH]c12 Show InChI InChI=1S/C22H22N6O2/c1-30-18-10-6-5-9-17(18)26-11-13-27(14-12-26)20-19-21(24-15-23-20)28(22(29)25-19)16-7-3-2-4-8-16/h2-10,15H,11-14H2,1H3,(H,25,29)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152827 (CHEMBL3781741) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(F)c1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-8-3-2-7-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-6-4-5-16(23)13-17/h2-8,13-15H,9-12H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair

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