Found 33 hits of ic50 data for polymerid = 50004536 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM445524
(2-{7-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-10-11-24-25(16-22)35(26-17-23(30(2,3)36)18-31-27(24)26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM445528
(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-fluoro-5-[...)Show SMILES Cc1nnn(C)c1-c1ccc2c3ncc(cc3n([C@@H](C3CCOCC3)c3ccccc3)c2c1F)C(C)(C)O |r,wU:18.19,(5.87,4.29,;5.87,2.75,;7.24,2.05,;7,.53,;5.48,.29,;4.71,-1.04,;4.78,1.66,;3.3,2.06,;2.82,3.52,;1.31,3.84,;.28,2.7,;-1.26,2.7,;-2.29,3.84,;-3.79,3.52,;-4.27,2.06,;-3.24,.92,;-1.73,1.24,;-.49,.33,;-.49,-1.21,;.85,-1.98,;2.18,-1.21,;3.51,-1.98,;3.51,-3.52,;2.18,-4.29,;.85,-3.52,;-1.82,-1.98,;-3.15,-1.21,;-4.49,-1.98,;-4.49,-3.52,;-3.15,-4.29,;-1.82,-3.52,;.76,1.24,;2.27,.92,;2.74,-.55,;-5.76,1.66,;-6.85,2.75,;-6.16,.17,;-7.24,1.26,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-27(35(4)34-33-18)22-10-11-23-26-24(16-21(17-32-26)30(2,3)37)36(29(23)25(22)31)28(19-8-6-5-7-9-19)20-12-14-38-15-13-20/h5-11,16-17,20,28,37H,12-15H2,1-4H3/t28-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50579853
(CHEMBL5075294)Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](CCC)c3ncccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.18,(54.77,-34.94,;56.32,-34.94,;57.07,-36.27,;55.78,-36.06,;57.04,-33.58,;58.57,-33.38,;58.84,-31.86,;57.49,-31.13,;57.28,-29.61,;56.38,-32.2,;54.86,-31.93,;53.87,-33.1,;52.35,-32.82,;51.14,-33.77,;51.2,-35.31,;49.89,-36.12,;48.54,-35.4,;47.23,-36.21,;52.55,-36.03,;53.85,-35.22,;55.21,-35.93,;55.27,-37.48,;53.96,-38.3,;52.6,-37.57,;51.29,-38.38,;49.87,-32.9,;48.39,-33.26,;47.33,-32.16,;47.76,-30.69,;49.25,-30.33,;50.3,-31.44,;51.84,-31.37,;52.83,-30.2,;54.34,-30.47,;55.33,-29.29,;45.84,-32.53,;45.41,-34.01,;44.34,-32.93,;44.77,-31.42,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM297146
(2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM445527
(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...)Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(5.87,4.1,;5.87,2.56,;7.24,1.86,;7,.34,;5.48,.1,;4.71,-1.23,;4.78,1.47,;3.3,1.87,;2.27,.73,;.76,1.05,;-.49,.14,;-.49,-1.4,;.85,-2.17,;2.18,-1.4,;3.51,-2.17,;3.51,-3.71,;2.18,-4.48,;.85,-3.71,;-1.82,-2.17,;-3.15,-1.4,;-4.49,-2.17,;-4.49,-3.71,;-3.15,-4.48,;-1.82,-3.71,;-1.73,1.05,;-3.24,.73,;-4.27,1.87,;-3.79,3.33,;-2.29,3.65,;-1.26,2.51,;.28,2.51,;1.31,3.65,;2.82,3.33,;3.85,4.48,;-5.76,1.47,;-6.85,2.56,;-6.16,-.02,;-7.24,1.07,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM445527
(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...)Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(5.87,4.1,;5.87,2.56,;7.24,1.86,;7,.34,;5.48,.1,;4.71,-1.23,;4.78,1.47,;3.3,1.87,;2.27,.73,;.76,1.05,;-.49,.14,;-.49,-1.4,;.85,-2.17,;2.18,-1.4,;3.51,-2.17,;3.51,-3.71,;2.18,-4.48,;.85,-3.71,;-1.82,-2.17,;-3.15,-1.4,;-4.49,-2.17,;-4.49,-3.71,;-3.15,-4.48,;-1.82,-3.71,;-1.73,1.05,;-3.24,.73,;-4.27,1.87,;-3.79,3.33,;-2.29,3.65,;-1.26,2.51,;.28,2.51,;1.31,3.65,;2.82,3.33,;3.85,4.48,;-5.76,1.47,;-6.85,2.56,;-6.16,-.02,;-7.24,1.07,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50579851
(CHEMBL5084198)Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ncccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.22,(13.75,-33.71,;15.3,-33.71,;16.06,-35.04,;14.76,-34.83,;16.03,-32.35,;17.55,-32.15,;17.83,-30.63,;16.47,-29.9,;16.26,-28.37,;15.36,-30.97,;13.85,-30.69,;12.85,-31.87,;11.34,-31.59,;10.13,-32.54,;10.18,-34.08,;8.87,-34.89,;7.52,-34.16,;6.22,-34.97,;6.26,-36.51,;7.62,-37.24,;8.93,-36.43,;11.54,-34.8,;12.84,-33.99,;14.19,-34.7,;14.25,-36.25,;12.94,-37.06,;11.58,-36.34,;10.27,-37.15,;8.85,-31.67,;7.37,-32.03,;6.32,-30.93,;6.75,-29.46,;8.23,-29.1,;9.29,-30.2,;10.82,-30.14,;11.81,-28.97,;13.32,-29.24,;14.31,-28.06,;4.82,-31.3,;4.39,-32.78,;3.32,-31.69,;3.75,-30.19,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50579852
(CHEMBL5090513)Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3cc(C)on3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.22,(33.12,-33.94,;34.66,-33.94,;35.42,-35.27,;34.12,-35.06,;35.39,-32.58,;36.91,-32.38,;37.19,-30.86,;35.83,-30.13,;35.62,-28.61,;34.72,-31.2,;33.21,-30.93,;32.21,-32.1,;30.7,-31.82,;29.49,-32.77,;29.54,-34.31,;28.23,-35.12,;26.88,-34.39,;25.58,-35.2,;25.62,-36.74,;26.98,-37.47,;28.29,-36.66,;30.9,-35.03,;31.11,-36.55,;32.63,-36.82,;33.3,-38.2,;33.35,-35.46,;32.29,-34.35,;28.21,-31.9,;26.73,-32.26,;25.68,-31.16,;26.11,-29.69,;27.6,-29.33,;28.65,-30.44,;30.18,-30.37,;31.17,-29.2,;32.68,-29.47,;33.67,-28.29,;24.18,-31.53,;23.75,-33.01,;22.68,-31.92,;23.12,-30.42,)| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM445515
(2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-9-fluoro-5-[...)Show SMILES Cc1nnn(C)c1-c1cc(F)c2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)21-14-23(31)26-24(15-21)36(25-16-22(30(2,3)37)17-32-27(25)26)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM331520
(2-{11-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-y...)Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cn1)C(C)(C)O |r| Show InChI InChI=1S/C29H32N6O2/c1-18-27(34(4)33-32-18)23-15-24-22(17-30-23)26-25(14-21(16-31-26)29(2,3)36)35(24)28(19-8-6-5-7-9-19)20-10-12-37-13-11-20/h5-9,14-17,20,28,36H,10-13H2,1-4H3/t28-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM445584
(US10683290, Example 77)Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1Cl)C(C)(C)O |r,wD:11.11,(4.65,-1.19,;5.42,.14,;6.95,.3,;7.27,1.81,;5.94,2.58,;6.34,4.07,;4.79,1.55,;3.29,1.87,;2.26,.73,;.75,1.05,;-.5,.14,;-.5,-1.4,;-1.83,-2.17,;-3.16,-1.4,;-4.5,-2.17,;-4.5,-3.71,;-3.16,-4.48,;-1.83,-3.71,;.84,-2.17,;.84,-3.71,;2.17,-4.48,;3.51,-3.71,;3.51,-2.17,;2.17,-1.4,;-1.74,1.05,;-3.25,.73,;-4.28,1.87,;-3.8,3.33,;-2.3,3.65,;-1.27,2.51,;.27,2.51,;1.31,3.65,;2.81,3.33,;3.84,4.48,;-5.78,1.55,;-6.81,2.69,;-7.27,1.15,;-6.26,.09,)| Show InChI InChI=1S/C30H32ClN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of c-MYC (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128376
BindingDB Entry DOI: 10.7270/Q2KS6WD7 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463126
(CHEMBL4238599)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)[N+]([O-])=O)-c1ccco1 Show InChI InChI=1S/C22H15N3O4/c23-22(26)16-5-3-14(4-6-16)17-12-19(15-7-9-18(10-8-15)25(27)28)24-20(13-17)21-2-1-11-29-21/h1-13H,(H2,23,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463135
(CHEMBL4243878)Show SMILES N#Cc1ccc(cc1)-c1cc(cc(n1)-c1ccco1)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C23H14N6O/c24-14-15-3-5-17(6-4-15)20-12-19(13-21(25-20)22-2-1-11-30-22)16-7-9-18(10-8-16)23-26-28-29-27-23/h1-13H,(H,26,27,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463127
(CHEMBL4237402)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)-c1cnco1)-c1ccco1 Show InChI InChI=1S/C25H17N3O3/c26-25(29)19-9-3-16(4-10-19)20-12-21(28-22(13-20)23-2-1-11-30-23)17-5-7-18(8-6-17)24-14-27-15-31-24/h1-15H,(H2,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463138
(CHEMBL4240401)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1ccco1 Show InChI InChI=1S/C23H15N3O2/c24-14-15-3-5-17(6-4-15)20-12-19(13-21(26-20)22-2-1-11-28-22)16-7-9-18(10-8-16)23(25)27/h1-13H,(H2,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463128
(CHEMBL4249055)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)-c1nccs1)-c1ccco1 Show InChI InChI=1S/C25H17N3O2S/c26-24(29)18-7-3-16(4-8-18)20-14-21(28-22(15-20)23-2-1-12-30-23)17-5-9-19(10-6-17)25-27-11-13-31-25/h1-15H,(H2,26,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463140
(CHEMBL4240109)Show SMILES N#Cc1ccc(cc1)-c1cc(cc(n1)-c1ccco1)-c1ccccc1 Show InChI InChI=1S/C22H14N2O/c23-15-16-8-10-18(11-9-16)20-13-19(17-5-2-1-3-6-17)14-21(24-20)22-7-4-12-25-22/h1-14H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463131
(CHEMBL4248559)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(n1)-c1ccco1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H14N4O2/c23-13-14-3-5-15(6-4-14)18-12-19(16-7-9-17(10-8-16)21(24)27)26-22(25-18)20-2-1-11-28-20/h1-12H,(H2,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463134
(CHEMBL4246868)Show SMILES CS(=O)(=O)NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1ccco1 Show InChI InChI=1S/C24H17N3O4S/c1-32(29,30)27-24(28)19-10-8-17(9-11-19)20-13-21(18-6-4-16(15-25)5-7-18)26-22(14-20)23-3-2-12-31-23/h2-14H,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463139
(CHEMBL4243533)Show InChI InChI=1S/C13H9N3O/c14-8-12-7-11(5-6-16-12)9-1-3-10(4-2-9)13(15)17/h1-7H,(H2,15,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463130
(CHEMBL4247460)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1cncs1 Show InChI InChI=1S/C22H14N4OS/c23-11-14-1-3-16(4-2-14)19-9-18(10-20(26-19)21-12-25-13-28-21)15-5-7-17(8-6-15)22(24)27/h1-10,12-13H,(H2,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM93880
(4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-benzoi...)Show SMILES OC(=O)c1ccc(Nc2ccc([N+]([O-])=O)c3nonc23)cc1 Show InChI InChI=1S/C13H8N4O5/c18-13(19)7-1-3-8(4-2-7)14-9-5-6-10(17(20)21)12-11(9)15-22-16-12/h1-6,14H,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimer... |
Bioorg Med Chem Lett 23: 370-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.013
BindingDB Entry DOI: 10.7270/Q2WM1FPM |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463141
(CHEMBL4244986)Show SMILES Cn1nncc1-c1cc(cc(n1)-c1ccc(cc1)C#N)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C22H16N6O/c1-28-21(13-25-27-28)20-11-18(15-6-8-17(9-7-15)22(24)29)10-19(26-20)16-4-2-14(12-23)3-5-16/h2-11,13H,1H3,(H2,24,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463129
(CHEMBL4245253)Show SMILES Cn1ccnc1-c1cc(cc(n1)-c1ccc(cc1)C#N)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C23H17N5O/c1-28-11-10-26-23(28)21-13-19(16-6-8-18(9-7-16)22(25)29)12-20(27-21)17-4-2-15(14-24)3-5-17/h2-13H,1H3,(H2,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50431277
((Z)-3,4,3'',5''-Tetramethoxystilbene | (Z)-3,4,3',...)Show InChI InChI=1S/C18H20O4/c1-19-15-9-14(10-16(12-15)20-2)6-5-13-7-8-17(21-3)18(11-13)22-4/h5-12H,1-4H3/b6-5- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi
Curated by ChEMBL
| Assay Description
Inhibition of Myc signaling pathway in human HeLa cells assessed as inhibition of PMA induced luciferase treated 30 mins before induction |
J Nat Prod 76: 679-84 (2013)
Article DOI: 10.1021/np300893n
BindingDB Entry DOI: 10.7270/Q2ZW1N83 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi
Curated by ChEMBL
| Assay Description
Inhibition of Myc signaling pathway in human HeLa cells assessed as inhibition of PMA induced luciferase treated 30 mins before induction |
J Nat Prod 76: 679-84 (2013)
Article DOI: 10.1021/np300893n
BindingDB Entry DOI: 10.7270/Q2ZW1N83 |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463124
(CHEMBL4248050)Show SMILES COc1ccc(cc1)-c1cc(nc(n1)-c1ccccc1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C24H19N3O2/c1-29-20-13-11-17(12-14-20)22-15-21(16-7-9-18(10-8-16)23(25)28)26-24(27-22)19-5-3-2-4-6-19/h2-15H,1H3,(H2,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463136
(CHEMBL4248116)Show SMILES c1coc(c1)-c1cc(cc(n1)-c1ccc(cc1)-c1nccs1)-c1nccs1 Show InChI InChI=1S/C21H13N3OS2/c1-2-19(25-9-1)18-13-16(21-23-8-11-27-21)12-17(24-18)14-3-5-15(6-4-14)20-22-7-10-26-20/h1-13H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463133
(CHEMBL4240576)Show SMILES NNC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1ccco1 Show InChI InChI=1S/C23H16N4O2/c24-14-15-3-5-17(6-4-15)20-12-19(13-21(26-20)22-2-1-11-29-22)16-7-9-18(10-8-16)23(28)27-25/h1-13H,25H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463132
(CHEMBL4250683)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1cccc(F)c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C25H16FN3O/c26-22-3-1-2-20(12-22)24-14-21(17-8-10-19(11-9-17)25(28)30)13-23(29-24)18-6-4-16(15-27)5-7-18/h1-14H,(H2,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463125
(CHEMBL4242611)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(n1)-c1cc[n+]([O-])cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H15N5O2/c24-14-15-1-3-16(4-2-15)20-13-21(17-5-7-18(8-6-17)22(25)29)27-23(26-20)19-9-11-28(30)12-10-19/h1-13H,(H2,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50463137
(CHEMBL4241092)Show SMILES NC(=O)c1ccc(cc1)-c1cc(nc(c1)-c1ccc(cc1)C#N)-c1cnco1 Show InChI InChI=1S/C22H14N4O2/c23-11-14-1-3-16(4-2-14)19-9-18(10-20(26-19)21-12-25-13-28-21)15-5-7-17(8-6-15)22(24)27/h1-10,12-13H,(H2,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity to ATG-Myc (unknown origin) expressed in CEF cells assessed as inhibition of microtumor formation |
Bioorg Med Chem 26: 4234-4239 (2018)
Article DOI: 10.1016/j.bmc.2018.07.019
BindingDB Entry DOI: 10.7270/Q2FJ2KDB |
More data for this
Ligand-Target Pair | |
Myc proto-oncogene protein
(Homo sapiens (Human)) | BDBM50423921
(CHEMBL2312756)Show SMILES [O-][N+](=O)c1ccc(Nc2ccccc2-c2ccccc2)c2nonc12 Show InChI InChI=1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.46E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland
Curated by ChEMBL
| Assay Description
Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimer... |
Bioorg Med Chem Lett 23: 370-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.013
BindingDB Entry DOI: 10.7270/Q2WM1FPM |
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Ligand-Target Pair | |
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