Compile Data Set for Download or QSAR

Found 35 hits of ic50 for UniProtKB: P22985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50320491 (2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...) Show SMILES CC(C)COc1ccc(cc1C#N)-c1nc(C)c(s1)C(O)=O Show InChI InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of rat xanthine oxidase				Bioorg Med Chem Lett 24: 1315-21 (2014) Article DOI: 10.1016/j.bmcl.2014.01.050 BindingDB Entry DOI: 10.7270/Q2V69M3N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50449104 (CHEMBL3127117) Show SMILES Nc1nc(c(Cl)c(=O)[nH]1)-c1ccc(OCC2CCOC2)c(OC(F)(F)F)c1 Show InChI InChI=1S/C16H15ClF3N3O4/c17-12-13(22-15(21)23-14(12)24)9-1-2-10(11(5-9)27-16(18,19)20)26-7-8-3-4-25-6-8/h1-2,5,8H,3-4,6-7H2,(H3,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of rat xanthine oxidase				Bioorg Med Chem Lett 24: 1315-21 (2014) Article DOI: 10.1016/j.bmcl.2014.01.050 BindingDB Entry DOI: 10.7270/Q2V69M3N
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333138 (2-((4-methoxyphenoxy)methyl)-7-methyl-5H-[1,3,4]th...) Show SMILES COc1ccc(OCc2nn3c(nc(C)cc3=O)s2)cc1 Show InChI InChI=1S/C14H13N3O3S/c1-9-7-13(18)17-14(15-9)21-12(16-17)8-20-11-5-3-10(19-2)4-6-11/h3-7H,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	289	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333141 (7-methyl-2-(o-tolyloxymethyl)-5H-[1,3,4]thiadiazol...) Show SMILES Cc1cc(=O)n2nc(COc3ccccc3C)sc2n1 Show InChI InChI=1S/C14H13N3O2S/c1-9-5-3-4-6-11(9)19-8-12-16-17-13(18)7-10(2)15-14(17)20-12/h3-7H,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	362	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333140 (2-((2-bromophenoxy)methyl)-7-methyl-5H-[1,3,4]thia...) Show SMILES Cc1cc(=O)n2nc(COc3ccccc3Br)sc2n1 Show InChI InChI=1S/C13H10BrN3O2S/c1-8-6-12(18)17-13(15-8)20-11(16-17)7-19-10-5-3-2-4-9(10)14/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	413	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333139 (2-((4-chlorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...) Show SMILES Cc1cc(=O)n2nc(COc3ccc(Cl)cc3)sc2n1 Show InChI InChI=1S/C13H10ClN3O2S/c1-8-6-12(18)17-13(15-8)20-11(16-17)7-19-10-4-2-9(14)3-5-10/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	449	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333137 (7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo[3...) Show SMILES Cc1cc(=O)n2nc(COc3ccccc3)sc2n1 Show InChI InChI=1S/C13H11N3O2S/c1-9-7-12(17)16-13(14-9)19-11(15-16)8-18-10-5-3-2-4-6-10/h2-7H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	555	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333147 (2-((2-fluorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...) Show SMILES Cc1cc(=O)n2nc(COc3ccccc3F)sc2n1 Show InChI InChI=1S/C13H10FN3O2S/c1-8-6-12(18)17-13(15-8)20-11(16-17)7-19-10-5-3-2-4-9(10)14/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333143 (2-((4-chloro-3-methylphenoxy)methyl)-7-methyl-5H-[...) Show SMILES Cc1cc(=O)n2nc(COc3ccc(Cl)c(C)c3)sc2n1 Show InChI InChI=1S/C14H12ClN3O2S/c1-8-5-10(3-4-11(8)15)20-7-12-17-18-13(19)6-9(2)16-14(18)21-12/h3-6H,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	623	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM35440 (ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...) Show SMILES O=c1[nH]cnc2n[nH]cc12 Show InChI InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	753	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333133 (7-methyl-2-(p-tolyloxymethyl)-5H-[1,3,4]thiadiazol...) Show SMILES Cc1ccc(OCc2nn3c(nc(C)cc3=O)s2)cc1 Show InChI InChI=1S/C14H13N3O2S/c1-9-3-5-11(6-4-9)19-8-12-16-17-13(18)7-10(2)15-14(17)20-12/h3-7H,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333144 (7-methyl-2-(m-tolyloxymethyl)-5H-[1,3,4]thiadiazol...) Show SMILES Cc1cccc(OCc2nn3c(nc(C)cc3=O)s2)c1 Show InChI InChI=1S/C14H13N3O2S/c1-9-4-3-5-11(6-9)19-8-12-16-17-13(18)7-10(2)15-14(17)20-12/h3-7H,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333146 (2-((2,4-dimethylphenoxy)methyl)-7-methyl-5H-[1,3,4...) Show SMILES Cc1ccc(OCc2nn3c(nc(C)cc3=O)s2)c(C)c1 Show InChI InChI=1S/C15H15N3O2S/c1-9-4-5-12(10(2)6-9)20-8-13-17-18-14(19)7-11(3)16-15(18)21-13/h4-7H,8H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333142 (2-((2-chlorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...) Show SMILES Cc1cc(=O)n2nc(COc3ccccc3Cl)sc2n1 Show InChI InChI=1S/C13H10ClN3O2S/c1-8-6-12(18)17-13(15-8)20-11(16-17)7-19-10-5-3-2-4-9(10)14/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333136 (2-((3-fluorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...) Show SMILES Cc1cc(=O)n2nc(COc3cccc(F)c3)sc2n1 Show InChI InChI=1S/C13H10FN3O2S/c1-8-5-12(18)17-13(15-8)20-11(16-17)7-19-10-4-2-3-9(14)6-10/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333145 (7-methyl-2-((4-nitrophenoxy)methyl)-5H-[1,3,4]thia...) Show SMILES Cc1cc(=O)n2nc(COc3ccc(cc3)[N+]([O-])=O)sc2n1 Show InChI InChI=1S/C13H10N4O4S/c1-8-6-12(18)16-13(14-8)22-11(15-16)7-21-10-4-2-9(3-5-10)17(19)20/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333135 (2-((3-bromophenoxy)methyl)-7-methyl-5H-[1,3,4]thia...) Show SMILES Cc1cc(=O)n2nc(COc3cccc(Br)c3)sc2n1 Show InChI InChI=1S/C13H10BrN3O2S/c1-8-5-12(18)17-13(15-8)20-11(16-17)7-19-10-4-2-3-9(14)6-10/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM35440 (ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...) Show SMILES O=c1[nH]cnc2n[nH]cc12 Show InChI InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50333134 (2-((3-chlorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...) Show SMILES Cc1cc(=O)n2nc(COc3cccc(Cl)c3)sc2n1 Show InChI InChI=1S/C13H10ClN3O2S/c1-8-5-12(18)17-13(15-8)20-11(16-17)7-19-10-4-2-3-9(14)6-10/h2-6H,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Mysore Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase by spectrophotometry				Bioorg Med Chem 19: 211-20 (2011) Article DOI: 10.1016/j.bmc.2010.11.034 BindingDB Entry DOI: 10.7270/Q26H4HPB
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423923 (CHEMBL2313040) Show SMILES CN(C)c1ccc(cc1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1SCc1ccccc1 |c:12| Show InChI InChI=1S/C31H26Cl2N4S3/c1-36(2)24-14-10-22(11-15-24)28-17-26(25-16-29(33)40-30(25)38-18-20-6-4-3-5-7-20)35-37(28)31-34-27(19-39-31)21-8-12-23(32)13-9-21/h3-16,19,28H,17-18H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423922 (CHEMBL2313041) Show SMILES CN(C)c1ccc(cc1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1S(N)(=O)=O |c:12| Show InChI InChI=1S/C24H21Cl2N5O2S3/c1-30(2)17-9-5-15(6-10-17)21-12-19(18-11-22(26)35-23(18)36(27,32)33)29-31(21)24-28-20(13-34-24)14-3-7-16(25)8-4-14/h3-11,13,21H,12H2,1-2H3,(H2,27,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423924 (CHEMBL2313039) Show SMILES CN(C)c1ccc(cc1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1Cl |c:12| Show InChI InChI=1S/C24H19Cl3N4S2/c1-30(2)17-9-5-15(6-10-17)21-12-19(18-11-22(26)33-23(18)27)29-31(21)24-28-20(13-32-24)14-3-7-16(25)8-4-14/h3-11,13,21H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423932 (CHEMBL2313031) Show SMILES CCCCc1nc(Cl)c([nH]1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1SCc1ccccc1 |c:13| Show InChI InChI=1S/C30H26Cl3N5S3/c1-2-3-9-26-35-27(28(33)36-26)24-15-22(21-14-25(32)41-29(21)39-16-18-7-5-4-6-8-18)37-38(24)30-34-23(17-40-30)19-10-12-20(31)13-11-19/h4-8,10-14,17,24H,2-3,9,15-16H2,1H3,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM35440 (ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...) Show SMILES O=c1[nH]cnc2n[nH]cc12 Show InChI InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacy School of Wenzhou Medical College Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometry				J Med Chem 52: 7732-52 (2009) Article DOI: 10.1021/jm900735p BindingDB Entry DOI: 10.7270/Q2CF9R2X
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423931 (CHEMBL2313032) Show SMILES CCCCc1nc(Cl)c([nH]1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1S(N)(=O)=O |c:13| Show InChI InChI=1S/C23H21Cl3N6O2S3/c1-2-3-4-19-29-20(21(26)30-19)17-10-15(14-9-18(25)36-22(14)37(27,33)34)31-32(17)23-28-16(11-35-23)12-5-7-13(24)8-6-12/h5-9,11,17H,2-4,10H2,1H3,(H,29,30)(H2,27,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423933 (CHEMBL2313030) Show SMILES CCCCc1nc(Cl)c([nH]1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1Cl |c:13| Show InChI InChI=1S/C23H19Cl4N5S2/c1-2-3-4-19-29-20(21(26)30-19)17-10-15(14-9-18(25)34-22(14)27)31-32(17)23-28-16(11-33-23)12-5-7-13(24)8-6-12/h5-9,11,17H,2-4,10H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423929 (CHEMBL2313034) Show SMILES Clc1cc(C2=NN(C(C2)c2ccc(Cl)cc2)c2nc(cs2)-c2ccc(Cl)cc2)c(SCc2ccccc2)s1 |t:4| Show InChI InChI=1S/C29H20Cl3N3S3/c30-21-10-6-19(7-11-21)25-17-37-29(33-25)35-26(20-8-12-22(31)13-9-20)15-24(34-35)23-14-27(32)38-28(23)36-16-18-4-2-1-3-5-18/h1-14,17,26H,15-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423928 (CHEMBL2313035) Show SMILES NS(=O)(=O)c1sc(Cl)cc1C1=NN(C(C1)c1ccc(Cl)cc1)c1nc(cs1)-c1ccc(Cl)cc1 |t:11| Show InChI InChI=1S/C22H15Cl3N4O2S3/c23-14-5-1-12(2-6-14)18-11-32-22(27-18)29-19(13-3-7-15(24)8-4-13)10-17(28-29)16-9-20(25)33-21(16)34(26,30)31/h1-9,11,19H,10H2,(H2,26,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423930 (CHEMBL2313033) Show SMILES Clc1cc(C2=NN(C(C2)c2ccc(Cl)cc2)c2nc(cs2)-c2ccc(Cl)cc2)c(Cl)s1 |t:4| Show InChI InChI=1S/C22H13Cl4N3S2/c23-14-5-1-12(2-6-14)18-11-30-22(27-18)29-19(13-3-7-15(24)8-4-13)10-17(28-29)16-9-20(25)31-21(16)26/h1-9,11,19H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423926 (CHEMBL2313037) Show SMILES Fc1ccc(cc1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1SCc1ccccc1 |c:10| Show InChI InChI=1S/C29H20Cl2FN3S3/c30-21-10-6-19(7-11-21)25-17-37-29(33-25)35-26(20-8-12-22(32)13-9-20)15-24(34-35)23-14-27(31)38-28(23)36-16-18-4-2-1-3-5-18/h1-14,17,26H,15-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423927 (CHEMBL2313036) Show SMILES Fc1ccc(cc1)C1CC(=NN1c1nc(cs1)-c1ccc(Cl)cc1)c1cc(Cl)sc1Cl |c:10| Show InChI InChI=1S/C22H13Cl3FN3S2/c23-14-5-1-12(2-6-14)18-11-30-22(27-18)29-19(13-3-7-15(26)8-4-13)10-17(28-29)16-9-20(24)31-21(16)25/h1-9,11,19H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50423925 (CHEMBL2313038) Show SMILES NS(=O)(=O)c1sc(Cl)cc1C1=NN(C(C1)c1ccc(F)cc1)c1nc(cs1)-c1ccc(Cl)cc1 |t:11| Show InChI InChI=1S/C22H15Cl2FN4O2S3/c23-14-5-1-12(2-6-14)18-11-32-22(27-18)29-19(13-3-7-15(25)8-4-13)10-17(28-29)16-9-20(24)33-21(16)34(26,30)31/h1-9,11,19H,10H2,(H2,26,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Swami Ramanand Teerth Marathwada University Curated by ChEMBL					Assay Description Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...				Bioorg Med Chem 21: 365-72 (2012) Article DOI: 10.1016/j.bmc.2012.09.060 BindingDB Entry DOI: 10.7270/Q2RV0Q0R
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50378419 (CHEMBL570882) Show SMILES CCOC(=O)COc1cc(O)c2c(c1)oc(-c1ccc3OC(CO)C(Oc3c1)c1ccc(OCC(=O)OCC)c(OC)c1)c(O)c2=O Show InChI InChI=1S/C33H32O14/c1-4-41-27(36)15-43-19-12-20(35)29-25(13-19)47-33(31(39)30(29)38)18-7-9-22-24(11-18)46-32(26(14-34)45-22)17-6-8-21(23(10-17)40-3)44-16-28(37)42-5-2/h6-13,26,32,34-35,39H,4-5,14-16H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacy School of Wenzhou Medical College Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometry				J Med Chem 52: 7732-52 (2009) Article DOI: 10.1021/jm900735p BindingDB Entry DOI: 10.7270/Q2CF9R2X
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM60989 ((3S)-2-[(2S,3S)-2-(hydroxymethyl)-3-(3-methoxy-4-o...) Show SMILES COc1cc(ccc1O)[C@@H]1Oc2cc(ccc2O[C@H]1CO)C1Oc2cc(O)cc(O)c2C(O)C1=O Show InChI InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,22,24-30H,10H2,1H3/t20-,22?,24-,25?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacy School of Wenzhou Medical College Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometry				J Med Chem 52: 7732-52 (2009) Article DOI: 10.1021/jm900735p BindingDB Entry DOI: 10.7270/Q2CF9R2X
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Rattus norvegicus)	BDBM50084979 (3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)...) Show SMILES COc1cc(ccc1O)C1Oc2cc(ccc2OC1CO)-c1oc2cc(O)cc(=O)c2c(O)c1O Show InChI InChI=1S/C25H20O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,24,26-28,30-31H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacy School of Wenzhou Medical College Curated by ChEMBL					Assay Description Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometry				J Med Chem 52: 7732-52 (2009) Article DOI: 10.1021/jm900735p BindingDB Entry DOI: 10.7270/Q2CF9R2X
					More data for this Ligand-Target Pair