Compile Data Set for Download or QSAR

Found 236 hits of ic50 for UniProtKB: Q8TF76   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50587785 (CHEMBL5178368) Show SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113318 BindingDB Entry DOI: 10.7270/Q25Q5115
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50603975 (CHEMBL5201780) Show SMILES CC1(N)CCN(CC1)c1nn2c(cnc2s1)-c1ccc(F)cc1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01995 BindingDB Entry DOI: 10.7270/Q2H70KXT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605473 (CHEMBL5186093) Show SMILES Nc1ccc2cc3cnccc3c([N+]([O-])=O)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50587785 (CHEMBL5178368) Show SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50246769 (CHEMBL4064608) Show SMILES C1CC(CCO1)c1c[nH]c2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c12 |r,wU:15.15,wD:18.22,(7.34,-15.64,;7.82,-17.1,;6.8,-18.25,;5.29,-17.94,;4.81,-16.48,;5.83,-15.33,;7.28,-19.71,;6.38,-20.97,;7.3,-22.21,;8.77,-21.73,;10.1,-22.5,;11.43,-21.72,;11.43,-20.18,;10.1,-19.41,;10.09,-17.87,;11.43,-17.1,;11.42,-15.56,;12.75,-14.8,;14.09,-15.57,;14.08,-17.11,;12.75,-17.87,;15.42,-14.8,;16.75,-15.58,;18.08,-14.82,;18.09,-13.28,;16.76,-12.5,;15.42,-13.27,;8.76,-20.18,)| Show InChI InChI=1S/C21H31N5O2/c1-3-17(26-7-11-28-12-8-26)4-2-16(1)25-21-19-18(15-5-9-27-10-6-15)13-22-20(19)23-14-24-21/h13-17H,1-12H2,(H2,22,23,24,25)/t16-,17-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal His6-tagged human haspin (471 end residues) expressed in baculovirus infected Sf21 insect cells				J Med Chem 60: 10071-10091 (2017) Article DOI: 10.1021/acs.jmedchem.7b01290 BindingDB Entry DOI: 10.7270/Q2T72KWX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50603974 (CHEMBL5201904) Show SMILES COc1ccc(cn1)-c1cnc2sc(N[C@@H]3CC[C@H](N)CC3)nn12 |r,wU:15.15,18.19,(-7.26,4.65,;-5.72,4.65,;-4.95,3.32,;-5.72,1.98,;-4.96,.65,;-3.42,.65,;-2.64,1.99,;-3.42,3.32,;-2.65,-.68,;-3.1,-2.13,;-1.86,-3.05,;-.65,-2.17,;.9,-2.18,;1.42,-.69,;2.91,-.3,;4,-1.38,;3.6,-2.87,;4.69,-3.96,;6.17,-3.56,;7.26,-4.65,;6.57,-2.07,;5.48,-.99,;.2,.22,;-1.11,-.68,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01995 BindingDB Entry DOI: 10.7270/Q2H70KXT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350270 (US10208056, Compound 105) Show SMILES CCn1c(C(N)=O)c(Cl)c2c1-c1ccncc1OC21CCCCC1 Show InChI InChI=1S/C18H20ClN3O2/c1-2-22-15-11-6-9-21-10-12(11)24-18(7-4-3-5-8-18)13(15)14(19)16(22)17(20)23/h6,9-10H,2-5,7-8H2,1H3,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.82	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350269 (US10208056, Compound 104) Show SMILES CCn1c(C(N)=O)c(Cl)c2c1-c1ccncc1OC21CCOCC1 Show InChI InChI=1S/C17H18ClN3O3/c1-2-21-14-10-3-6-20-9-11(10)24-17(4-7-23-8-5-17)12(14)13(18)15(21)16(19)22/h3,6,9H,2,4-5,7-8H2,1H3,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.91	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350253 (US10208056, Compound 80) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O Show InChI InChI=1S/C18H21N3O2/c1-2-21-14(17(19)22)10-13-16(21)12-6-9-20-11-15(12)23-18(13)7-4-3-5-8-18/h6,9-11H,2-5,7-8H2,1H3,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.56	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350256 (US10208056, Compound 83) Show SMILES Cn1c(cc2c1-c1ccncc1OC21CCCCC1)C(N)=O Show InChI InChI=1S/C17H19N3O2/c1-20-13(16(18)21)9-12-15(20)11-5-8-19-10-14(11)22-17(12)6-3-2-4-7-17/h5,8-10H,2-4,6-7H2,1H3,(H2,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50442760 (CHEMBL2443044) Show SMILES CN1CCC(CC1)NC(=O)c1cc(on1)-c1c(O)cc(O)cc1Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C22H22N4O7/c1-25-8-6-13(7-9-25)23-22(29)17-12-20(33-24-17)21-18(28)10-15(27)11-19(21)32-16-4-2-14(3-5-16)26(30)31/h2-5,10-13,27-28H,6-9H2,1H3,(H,23,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences S.r.l. Curated by ChEMBL					Assay Description Inhibition of haspin (V473 to K798) (unknown origin)				Bioorg Med Chem 21: 7047-63 (2013) Article DOI: 10.1016/j.bmc.2013.09.018 BindingDB Entry DOI: 10.7270/Q2V989HZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50442757 (CHEMBL2443026) Show SMILES CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(CC2)C2CCC3(CC2)OCCO3)cc1 Show InChI InChI=1S/C31H38N4O7/c1-34(2)21-3-5-24(6-4-21)41-27-18-23(36)17-26(37)29(27)28-19-25(33-42-28)30(38)32-20-9-13-35(14-10-20)22-7-11-31(12-8-22)39-15-16-40-31/h3-6,17-20,22,36-37H,7-16H2,1-2H3,(H,32,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences S.r.l. Curated by ChEMBL					Assay Description Inhibition of haspin (V473 to K798) (unknown origin)				Bioorg Med Chem 21: 7047-63 (2013) Article DOI: 10.1016/j.bmc.2013.09.018 BindingDB Entry DOI: 10.7270/Q2V989HZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50442758 (CHEMBL2443139) Show SMILES CC(C)Nc1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(C)CC2)cc1 Show InChI InChI=1S/C25H30N4O5/c1-15(2)26-16-4-6-19(7-5-16)33-22-13-18(30)12-21(31)24(22)23-14-20(28-34-23)25(32)27-17-8-10-29(3)11-9-17/h4-7,12-15,17,26,30-31H,8-11H2,1-3H3,(H,27,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences S.r.l. Curated by ChEMBL					Assay Description Inhibition of haspin (V473 to K798) (unknown origin)				Bioorg Med Chem 21: 7047-63 (2013) Article DOI: 10.1016/j.bmc.2013.09.018 BindingDB Entry DOI: 10.7270/Q2V989HZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50442759 (CHEMBL2443138) Show SMILES CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(C)CC2)cc1 Show InChI InChI=1S/C24H28N4O5/c1-27(2)16-4-6-18(7-5-16)32-21-13-17(29)12-20(30)23(21)22-14-19(26-33-22)24(31)25-15-8-10-28(3)11-9-15/h4-7,12-15,29-30H,8-11H2,1-3H3,(H,25,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences S.r.l. Curated by ChEMBL					Assay Description Inhibition of haspin (V473 to K798) (unknown origin)				Bioorg Med Chem 21: 7047-63 (2013) Article DOI: 10.1016/j.bmc.2013.09.018 BindingDB Entry DOI: 10.7270/Q2V989HZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50603992 (CHEMBL5179988) Show SMILES CC(C)(N)CNc1nn2c(cnc2s1)-c1ccc(F)cc1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01995 BindingDB Entry DOI: 10.7270/Q2H70KXT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50466167 (CHEMBL4278808) Show SMILES Oc1ccc(c(F)c1)-c1nc2ccc3[nH]ncc3c2c2CCCCc12 Show InChI InChI=1S/C20H16FN3O/c21-16-9-11(25)5-6-14(16)20-13-4-2-1-3-12(13)19-15-10-22-24-17(15)7-8-18(19)23-20/h5-10,25H,1-4H2,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of Haspin (unknown origin) after 3 hrs by ADP-Glo assay				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605464 (CHEMBL5188318) Show SMILES CSc1ncc2cc3cnccc3c(N)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350255 (US10208056, Compound 82) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCOCC1)C(N)=O Show InChI InChI=1S/C17H19N3O3/c1-2-20-13(16(18)21)9-12-15(20)11-3-6-19-10-14(11)23-17(12)4-7-22-8-5-17/h3,6,9-10H,2,4-5,7-8H2,1H3,(H2,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.8	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50542441 (CHEMBL4642838) Show SMILES Oc1ccc2C(=O)\C(Oc2c1)=C\c1c[nH]c2ncccc12 Show InChI InChI=1S/C16H10N2O3/c19-10-3-4-12-13(7-10)21-14(15(12)20)6-9-8-18-16-11(9)2-1-5-17-16/h1-8,19H,(H,17,18)/b14-6-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Inhibition of human recombinant Haspin (470 to 798 residues) expressed in bacteria using Histone H3 and ARTKQTARKSTGGKAPRKQLA as substrate in presenc...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115468 BindingDB Entry DOI: 10.7270/Q28G8Q87
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350183 (US10208056, Compound 15) Show SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCC1 Show InChI InChI=1S/C14H13N3O2/c15-13(18)10-6-9-12(17-10)8-2-5-16-7-11(8)19-14(9)3-1-4-14/h2,5-7,17H,1,3-4H2,(H2,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.9	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350264 (US10208056, Compound 91) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCNCC1)C(N)=O Show InChI InChI=1S/C17H20N4O2/c1-2-21-13(16(18)22)9-12-15(21)11-3-6-20-10-14(11)23-17(12)4-7-19-8-5-17/h3,6,9-10,19H,2,4-5,7-8H2,1H3,(H2,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350266 (US10208056, Compound 94) Show SMILES CCn1c(C(N)=O)c(C2CC2)c2c1-c1ccncc1OC2(C)C Show InChI InChI=1S/C18H21N3O2/c1-4-21-15-11-7-8-20-9-12(11)23-18(2,3)14(15)13(10-5-6-10)16(21)17(19)22/h7-10H,4-6H2,1-3H3,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Gachon University Curated by ChEMBL					Assay Description Inhibition of human haspin using Histone H3 as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 163: 453-480 (2019) Article DOI: 10.1016/j.ejmech.2018.11.037 BindingDB Entry DOI: 10.7270/Q2TQ650N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Gachon University Curated by ChEMBL					Assay Description Inhibition of human haspin using Histone H3 as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 163: 453-480 (2019) Article DOI: 10.1016/j.ejmech.2018.11.037 BindingDB Entry DOI: 10.7270/Q2TQ650N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350220 (US10208056, Compound 52) Show SMILES CC1(C)Oc2cnccc2-c2c1cc(C(N)=O)n2CCF Show InChI InChI=1S/C15H16FN3O2/c1-15(2)10-7-11(14(17)20)19(6-4-16)13(10)9-3-5-18-8-12(9)21-15/h3,5,7-8H,4,6H2,1-2H3,(H2,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.4	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350249 (US10208056, Compound 76) Show SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCC2)n1CCF Show InChI InChI=1S/C16H16FN3O2/c17-5-7-20-12(15(18)21)8-11-14(20)10-2-6-19-9-13(10)22-16(11)3-1-4-16/h2,6,8-9H,1,3-5,7H2,(H2,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.2	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350265 (US10208056, Compound 92) Show SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCOCC2)n1CCF Show InChI InChI=1S/C17H18FN3O3/c18-4-6-21-13(16(19)22)9-12-15(21)11-1-5-20-10-14(11)24-17(12)2-7-23-8-3-17/h1,5,9-10H,2-4,6-8H2,(H2,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.6	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350239 (US10208056, Compound 66) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCC1)C(N)=O Show InChI InChI=1S/C16H17N3O2/c1-2-19-12(15(17)20)8-11-14(19)10-4-7-18-9-13(10)21-16(11)5-3-6-16/h4,7-9H,2-3,5-6H2,1H3,(H2,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.2	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350196 (US10208056, Compound 28) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(N)=O)c(Cl)c12 Show InChI InChI=1S/C13H12ClN3O2/c1-13(2)8-9(14)11(12(15)18)17-10(8)6-3-4-16-5-7(6)19-13/h3-5,17H,1-2H3,(H2,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.6	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350240 (US10208056, Compound 67) Show SMILES Cn1c(cc2c1-c1ccncc1OC21CCC1)C(N)=O Show InChI InChI=1S/C15H15N3O2/c1-18-11(14(16)19)7-10-13(18)9-3-6-17-8-12(9)20-15(10)4-2-5-15/h3,6-8H,2,4-5H2,1H3,(H2,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.6	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350202 (US10208056, Compound 34) Show SMILES CC1(C)Oc2cncc(Cl)c2-c2[nH]c(cc12)C(N)=O Show InChI InChI=1S/C13H12ClN3O2/c1-13(2)6-3-8(12(15)18)17-11(6)10-7(14)4-16-5-9(10)19-13/h3-5,17H,1-2H3,(H2,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.8	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50603978 (CHEMBL5187817) Show SMILES COc1ccc(-c2cnc3sc(nn23)N2CCC(C)(N)CC2)c(F)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01995 BindingDB Entry DOI: 10.7270/Q2H70KXT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human haspin using Histone H3 as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50364776 (CHEMBL1952141 | CHEMBL1952329) Show SMILES CN1CCC(CNc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 Show InChI InChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of haspin				J Med Chem 55: 8199-208 (2012) Article DOI: 10.1021/jm3009234 BindingDB Entry DOI: 10.7270/Q2930V9T
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350259 (US10208056, Compound 86) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(N)=O)c(C3CC3)c12 Show InChI InChI=1S/C16H17N3O2/c1-16(2)12-11(8-3-4-8)14(15(17)20)19-13(12)9-5-6-18-7-10(9)21-16/h5-8,19H,3-4H2,1-2H3,(H2,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.5	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50466158 (CHEMBL4290247) Show SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1 Show InChI InChI=1S/C22H16FN3OS/c23-19-5-3-15(4-6-19)8-22(27)26-20-9-17(12-25-13-20)21-10-18(14-28-21)16-2-1-7-24-11-16/h1-7,9-14H,8H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant human Haspin expressed in Baculovirus expression system by Adapta assay				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350211 (US10208056, Compound 43) Show SMILES CCn1c(cc2c1-c1ccncc1OC2(C)C)C(N)=O Show InChI InChI=1S/C15H17N3O2/c1-4-18-11(14(16)19)7-10-13(18)9-5-6-17-8-12(9)20-15(10,2)3/h5-8H,4H2,1-3H3,(H2,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.8	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350169 (US10208056, Compound 1) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(cc12)C(N)=O Show InChI InChI=1S/C13H13N3O2/c1-13(2)8-5-9(12(14)17)16-11(8)7-3-4-15-6-10(7)18-13/h3-6,16H,1-2H3,(H2,14,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.1	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350252 (US10208056, Compound 79) Show SMILES CCn1c(cc2c1-c1ccncc1OC21CCN(CC(F)(F)F)CC1)C(N)=O Show InChI InChI=1S/C19H21F3N4O2/c1-2-26-14(17(23)27)9-13-16(26)12-3-6-24-10-15(12)28-18(13)4-7-25(8-5-18)11-19(20,21)22/h3,6,9-10H,2,4-5,7-8,11H2,1H3,(H2,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.6	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350257 (US10208056, Compound 84) Show SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCCCC2)n1CCF Show InChI InChI=1S/C18H20FN3O2/c19-7-9-22-14(17(20)23)10-13-16(22)12-4-8-21-11-15(12)24-18(13)5-2-1-3-6-18/h4,8,10-11H,1-3,5-7,9H2,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.1	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50603989 (CHEMBL5192443) Show SMILES CC1(N)CCN(CC1)c1nn2c(cnc2s1)C1=CCCCC1 |t:19| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01995 BindingDB Entry DOI: 10.7270/Q2H70KXT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605471 (CHEMBL5181620) Show SMILES COc1ncc2cc3cnccc3c([N+]([O-])=O)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350224 (US10208056, Compound 54) Show SMILES CC(C)C1(C)Oc2cnccc2-c2[nH]c(cc12)C(N)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52.9	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350180 (US10208056, Compound 12) Show SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCNCC1 Show InChI InChI=1S/C15H16N4O2/c16-14(20)11-7-10-13(19-11)9-1-4-18-8-12(9)21-15(10)2-5-17-6-3-15/h1,4,7-8,17,19H,2-3,5-6H2,(H2,16,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53.3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350181 (US10208056, Compound 13) Show SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCCCC1 Show InChI InChI=1S/C16H17N3O2/c17-15(20)12-8-11-14(19-12)10-4-7-18-9-13(10)21-16(11)5-2-1-3-6-16/h4,7-9,19H,1-3,5-6H2,(H2,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53.6	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605467 (CHEMBL5177344) Show SMILES CC(C)Sc1ncc2cc3cnccc3c(N)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605466 (CHEMBL5194011) Show SMILES CCCSc1ncc2cc3cnccc3c(N)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605471 (CHEMBL5181620) Show SMILES COc1ncc2cc3cnccc3c([N+]([O-])=O)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50605468 (CHEMBL5186471) Show SMILES CCCCSc1ncc2cc3cnccc3c(N)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM350199 (US10208056, Compound 31) Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(N)=O)c(c12)-c1ccccc1 Show InChI InChI=1S/C19H17N3O2/c1-19(2)15-14(11-6-4-3-5-7-11)17(18(20)23)22-16(15)12-8-9-21-10-13(12)24-19/h3-10,22H,1-2H3,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	73.2	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO) US Patent					Assay Description The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...				US Patent US10208056 (2019) BindingDB Entry DOI: 10.7270/Q2GB266B
					More data for this Ligand-Target Pair

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