Compile Data Set for Download or QSAR

Found 34 hits of ic50 data for polymerid = 50004795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394308 (CHEMBL2159379) Show SMILES COc1cccc(CNS(=O)(=O)c2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C15H17N3O3S/c1-21-13-6-2-4-11(8-13)10-18-22(19,20)14-7-3-5-12(9-14)15(16)17/h2-9,18H,10H2,1H3,(H3,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394307 (CHEMBL2159380) Show SMILES COc1ccc(CNS(=O)(=O)c2cccc(c2)C(N)=N)cc1OC Show InChI InChI=1S/C16H19N3O4S/c1-22-14-7-6-11(8-15(14)23-2)10-19-24(20,21)13-5-3-4-12(9-13)16(17)18/h3-9,19H,10H2,1-2H3,(H3,17,18)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394310 (CHEMBL2159377) Show SMILES NC(=N)c1cccc(c1)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C14H15N3O2S/c15-14(16)12-7-4-8-13(9-12)20(18,19)17-10-11-5-2-1-3-6-11/h1-9,17H,10H2,(H3,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394311 (CHEMBL2159376) Show SMILES COc1ccc(NS(=O)(=O)c2cccc(c2)C(N)=N)cc1OC Show InChI InChI=1S/C15H17N3O4S/c1-21-13-7-6-11(9-14(13)22-2)18-23(19,20)12-5-3-4-10(8-12)15(16)17/h3-9,18H,1-2H3,(H3,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394312 (CHEMBL2159375) Show SMILES COc1cccc(NS(=O)(=O)c2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C14H15N3O3S/c1-20-12-6-3-5-11(9-12)17-21(18,19)13-7-2-4-10(8-13)14(15)16/h2-9,17H,1H3,(H3,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394313 (CHEMBL2159374) Show SMILES COc1ccc(NS(=O)(=O)c2cccc(c2)C(N)=N)cc1 Show InChI InChI=1S/C14H15N3O3S/c1-20-12-7-5-11(6-8-12)17-21(18,19)13-4-2-3-10(9-13)14(15)16/h2-9,17H,1H3,(H3,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394314 (CHEMBL2159373) Show SMILES NC(=N)c1cccc(c1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C13H13N3O2S/c14-13(15)10-5-4-8-12(9-10)19(17,18)16-11-6-2-1-3-7-11/h1-9,16H,(H3,14,15)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394315 (CHEMBL2159372) Show SMILES COc1ccc(CNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C16H19N3O4S/c1-22-14-8-3-11(9-15(14)23-2)10-19-24(20,21)13-6-4-12(5-7-13)16(17)18/h3-9,19H,10H2,1-2H3,(H3,17,18)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394316 (CHEMBL2159371) Show SMILES COc1cccc(CNS(=O)(=O)c2ccc(cc2)C(N)=N)c1 Show InChI InChI=1S/C15H17N3O3S/c1-21-13-4-2-3-11(9-13)10-18-22(19,20)14-7-5-12(6-8-14)15(16)17/h2-9,18H,10H2,1H3,(H3,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394317 (CHEMBL2159370) Show SMILES COc1ccc(CNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1 Show InChI InChI=1S/C15H17N3O3S/c1-21-13-6-2-11(3-7-13)10-18-22(19,20)14-8-4-12(5-9-14)15(16)17/h2-9,18H,10H2,1H3,(H3,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394318 (CHEMBL2159369) Show SMILES NC(=N)c1ccc(cc1)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C14H15N3O2S/c15-14(16)12-6-8-13(9-7-12)20(18,19)17-10-11-4-2-1-3-5-11/h1-9,17H,10H2,(H3,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394319 (CHEMBL2159368) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C15H17N3O4S/c1-21-13-8-5-11(9-14(13)22-2)18-23(19,20)12-6-3-10(4-7-12)15(16)17/h3-9,18H,1-2H3,(H3,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394320 (CHEMBL2159367) Show SMILES COc1cccc(NS(=O)(=O)c2ccc(cc2)C(N)=N)c1 Show InChI InChI=1S/C14H15N3O3S/c1-20-12-4-2-3-11(9-12)17-21(18,19)13-7-5-10(6-8-13)14(15)16/h2-9,17H,1H3,(H3,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394321 (CHEMBL2159366) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(cc2)C(N)=N)cc1 Show InChI InChI=1S/C14H15N3O3S/c1-20-12-6-4-11(5-7-12)17-21(18,19)13-8-2-10(3-9-13)14(15)16/h2-9,17H,1H3,(H3,15,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394264 (CHEMBL2159361) Show SMILES NC(=[NH2+])c1cccc(c1)S(=O)(=O)NCCCC(=O)Nc1cccc(c1)C(O)=O Show InChI InChI=1S/C18H20N4O5S/c19-17(20)12-4-2-7-15(11-12)28(26,27)21-9-3-8-16(23)22-14-6-1-5-13(10-14)18(24)25/h1-2,4-7,10-11,21H,3,8-9H2,(H3,19,20)(H,22,23)(H,24,25)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394270 (CHEMBL2159300) Show SMILES NC(=[NH2+])c1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc1cccc(c1)C(O)=O Show InChI InChI=1S/C18H20N4O5S/c19-17(20)12-6-8-15(9-7-12)28(26,27)21-10-2-5-16(23)22-14-4-1-3-13(11-14)18(24)25/h1,3-4,6-9,11,21H,2,5,10H2,(H3,19,20)(H,22,23)(H,24,25)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394271 (CHEMBL2159299) Show SMILES NC(=[NH2+])c1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C18H20N4O5S/c19-17(20)12-5-9-15(10-6-12)28(26,27)21-11-1-2-16(23)22-14-7-3-13(4-8-14)18(24)25/h3-10,21H,1-2,11H2,(H3,19,20)(H,22,23)(H,24,25)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394272 (CHEMBL2159298) Show SMILES NC(=[NH2+])c1ccc(cc1)S(=O)(=O)NCCC(=O)Nc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H18N4O5S/c18-16(19)11-4-6-14(7-5-11)27(25,26)20-9-8-15(22)21-13-3-1-2-12(10-13)17(23)24/h1-7,10,20H,8-9H2,(H3,18,19)(H,21,22)(H,23,24)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394273 (CHEMBL2159297) Show SMILES NC(=[NH2+])c1ccc(cc1)S(=O)(=O)NCCC(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C17H18N4O5S/c18-16(19)11-3-7-14(8-4-11)27(25,26)20-10-9-15(22)21-13-5-1-12(2-6-13)17(23)24/h1-8,20H,9-10H2,(H3,18,19)(H,21,22)(H,23,24)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394274 (CHEMBL2159296) Show SMILES NC(=[NH2+])c1ccc(cc1)S(=O)(=O)NCC(=O)Nc1cccc(c1)C(O)=O Show InChI InChI=1S/C16H16N4O5S/c17-15(18)10-4-6-13(7-5-10)26(24,25)19-9-14(21)20-12-3-1-2-11(8-12)16(22)23/h1-8,19H,9H2,(H3,17,18)(H,20,21)(H,22,23)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394275 (CHEMBL2159295) Show SMILES NC(=[NH2+])c1ccc(cc1)S(=O)(=O)NCC(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H16N4O5S/c17-15(18)10-3-7-13(8-4-10)26(24,25)19-9-14(21)20-12-5-1-11(2-6-12)16(22)23/h1-8,19H,9H2,(H3,17,18)(H,20,21)(H,22,23)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394276 (CHEMBL2159294) Show SMILES CC(C)(C)OC(=O)c1cccc(NC(=O)CCCNS(=O)(=O)c2cccc(c2)C(N)=[NH2+])c1 Show InChI InChI=1S/C22H28N4O5S/c1-22(2,3)31-21(28)16-8-4-9-17(13-16)26-19(27)11-6-12-25-32(29,30)18-10-5-7-15(14-18)20(23)24/h4-5,7-10,13-14,25H,6,11-12H2,1-3H3,(H3,23,24)(H,26,27)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394282 (CHEMBL2159288) Show SMILES CC(C)(C)OC(=O)c1cccc(NC(=O)CCCNS(=O)(=O)c2ccc(cc2)C(N)=[NH2+])c1 Show InChI InChI=1S/C22H28N4O5S/c1-22(2,3)31-21(28)16-6-4-7-17(14-16)26-19(27)8-5-13-25-32(29,30)18-11-9-15(10-12-18)20(23)24/h4,6-7,9-12,14,25H,5,8,13H2,1-3H3,(H3,23,24)(H,26,27)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394284 (CHEMBL2159286) Show SMILES CC(C)(C)OC(=O)c1cccc(NC(=O)CCNS(=O)(=O)c2ccc(cc2)C(N)=[NH2+])c1 Show InChI InChI=1S/C21H26N4O5S/c1-21(2,3)30-20(27)15-5-4-6-16(13-15)25-18(26)11-12-24-31(28,29)17-9-7-14(8-10-17)19(22)23/h4-10,13,24H,11-12H2,1-3H3,(H3,22,23)(H,25,26)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394285 (CHEMBL2159285) Show SMILES CC(C)(C)OC(=O)c1ccc(NC(=O)CCNS(=O)(=O)c2ccc(cc2)C(N)=[NH2+])cc1 Show InChI InChI=1S/C21H26N4O5S/c1-21(2,3)30-20(27)15-4-8-16(9-5-15)25-18(26)12-13-24-31(28,29)17-10-6-14(7-11-17)19(22)23/h4-11,24H,12-13H2,1-3H3,(H3,22,23)(H,25,26)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394286 (CHEMBL2159284) Show SMILES CC(C)(C)OC(=O)c1cccc(NC(=O)CNS(=O)(=O)c2ccc(cc2)C(N)=[NH2+])c1 Show InChI InChI=1S/C20H24N4O5S/c1-20(2,3)29-19(26)14-5-4-6-15(11-14)24-17(25)12-23-30(27,28)16-9-7-13(8-10-16)18(21)22/h4-11,23H,12H2,1-3H3,(H3,21,22)(H,24,25)/p+1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394295 (CHEMBL2159392) Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2cccc(c2)C(N)=N)cc1OC Show InChI InChI=1S/C20H26N4O5S/c1-28-17-9-8-14(11-18(17)29-2)13-23-19(25)7-4-10-24-30(26,27)16-6-3-5-15(12-16)20(21)22/h3,5-6,8-9,11-12,24H,4,7,10,13H2,1-2H3,(H3,21,22)(H,23,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394297 (CHEMBL2159390) Show SMILES COc1ccc(NC(=O)CCCNS(=O)(=O)c2cccc(c2)C(N)=N)cc1OC Show InChI InChI=1S/C19H24N4O5S/c1-27-16-9-8-14(12-17(16)28-2)23-18(24)7-4-10-22-29(25,26)15-6-3-5-13(11-15)19(20)21/h3,5-6,8-9,11-12,22H,4,7,10H2,1-2H3,(H3,20,21)(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394301 (CHEMBL2159386) Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C20H26N4O5S/c1-28-17-10-5-14(12-18(17)29-2)13-23-19(25)4-3-11-24-30(26,27)16-8-6-15(7-9-16)20(21)22/h5-10,12,24H,3-4,11,13H2,1-2H3,(H3,21,22)(H,23,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394302 (CHEMBL2159385) Show SMILES COc1ccc(CNC(=O)CCNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C19H24N4O5S/c1-27-16-8-3-13(11-17(16)28-2)12-22-18(24)9-10-23-29(25,26)15-6-4-14(5-7-15)19(20)21/h3-8,11,23H,9-10,12H2,1-2H3,(H3,20,21)(H,22,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394303 (CHEMBL2159384) Show SMILES COc1ccc(NC(=O)CCCNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C19H24N4O5S/c1-27-16-10-7-14(12-17(16)28-2)23-18(24)4-3-11-22-29(25,26)15-8-5-13(6-9-15)19(20)21/h5-10,12,22H,3-4,11H2,1-2H3,(H3,20,21)(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394304 (CHEMBL2159383) Show SMILES COc1ccc(CNC(=O)CNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C18H22N4O5S/c1-26-15-8-3-12(9-16(15)27-2)10-21-17(23)11-22-28(24,25)14-6-4-13(5-7-14)18(19)20/h3-9,22H,10-11H2,1-2H3,(H3,19,20)(H,21,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394305 (CHEMBL2159382) Show SMILES COc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC Show InChI InChI=1S/C18H22N4O5S/c1-26-15-8-5-13(11-16(15)27-2)22-17(23)9-10-21-28(24,25)14-6-3-12(4-7-14)18(19)20/h3-8,11,21H,9-10H2,1-2H3,(H3,19,20)(H,22,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair
Transmembrane protease serine 6 (Homo sapiens (Human))	BDBM50394309 (CHEMBL2159378) Show SMILES COc1ccc(CNS(=O)(=O)c2cccc(c2)C(N)=N)cc1 Show InChI InChI=1S/C15H17N3O3S/c1-21-13-7-5-11(6-8-13)10-18-22(19,20)14-4-2-3-12(9-14)15(16)17/h2-9,18H,10H2,1H3,(H3,16,17)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...				Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD
					More data for this Ligand-Target Pair