Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UDP-glucuronosyltransferase 1A9 (Homo sapiens (Human)) | BDBM50511112 (CHEMBL4567446) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of UGT1A9 in human liver microsomes incubated for 30 mins in presence of UDPGA by LC-MS/MS analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00640 BindingDB Entry DOI: 10.7270/Q2RR22VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-glucuronosyltransferase 1A9 (Homo sapiens (Human)) | BDBM50508419 (CHEMBL4471264) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gwangju Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of UGT1A9 in human liver microsomes assessed as reduction in mycophenolic acid glucuronidation by tandem mass spectrometry analysis | J Med Chem 62: 575-588 (2019) Article DOI: 10.1021/acs.jmedchem.8b01168 BindingDB Entry DOI: 10.7270/Q2QZ2F8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
UDP-glucuronosyltransferase 1A9 (Homo sapiens (Human)) | BDBM50103451 (CHEMBL3398252) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibition of of UGT1A9 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC method | Bioorg Med Chem Lett 25: 1269-73 (2015) Article DOI: 10.1016/j.bmcl.2015.01.050 BindingDB Entry DOI: 10.7270/Q2KW5HTQ | |||||||||||
More data for this Ligand-Target Pair |