BindingDB PrimarySearch

Found 8 hits of ic50 for UniProtKB: P00573
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50356642 (CHEMBL1917196) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase using salmon sperm DNA and [3H]UTP at 25 degree C after 30 mins by liquid scintillation counting				Bioorg Med Chem 19: 5803-12 (2011) Article DOI: 10.1016/j.bmc.2011.08.023 BindingDB Entry DOI: 10.7270/Q2DZ0989
Kyoto Prefectural University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50356643 (CHEMBL1917198) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase using salmon sperm DNA and [3H]UTP at 25 degree C after 30 mins by liquid scintillation counting				Bioorg Med Chem 19: 5803-12 (2011) Article DOI: 10.1016/j.bmc.2011.08.023 BindingDB Entry DOI: 10.7270/Q2DZ0989
Kyoto Prefectural University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50448689 (CHEMBL3127730) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50448690 (CHEMBL3127728) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50448691 (CHEMBL3127729) Show SMILES C\C(\C=C\CCC(=O)N1CCCC1=O)=C/C1CCCCO1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50448688 (Pecilocin \| Variotin) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins				Bioorg Med Chem 22: 1070-6 (2014) Article DOI: 10.1016/j.bmc.2013.12.038 BindingDB Entry DOI: 10.7270/Q22V2HMW
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50262634 (CHEMBL4076797) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Department of Life Science and Technology, Tokyo Institute of Technology, 4259, Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as reduction in RNA product formation using double stranded DNA as substrate after 4 hrs in presence of NTPs...				Bioorg Med Chem 25: 6007-6015 (2017) Article DOI: 10.1016/j.bmc.2017.09.032 BindingDB Entry DOI: 10.7270/Q2KK9F84
					More data for this Ligand-Target Pair
T7 RNA polymerase (Enterobacteria phage T7)	BDBM50262635 (CHEMBL4095030) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Department of Life Science and Technology, Tokyo Institute of Technology, 4259, Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. Curated by ChEMBL					Assay Description Inhibition of T7 RNA polymerase assessed as reduction in RNA product formation using double stranded DNA as substrate after 4 hrs in presence of NTPs...				Bioorg Med Chem 25: 6007-6015 (2017) Article DOI: 10.1016/j.bmc.2017.09.032 BindingDB Entry DOI: 10.7270/Q2KK9F84
					More data for this Ligand-Target Pair