Found 17 hits of ki for UniProtKB: P11064 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371120
(CHEMBL242173)Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1cccc(Br)c1 |w:13.12,9.9,8.18,c:11| Show InChI InChI=1S/C19H16BrNO2/c20-13-4-1-3-11(9-13)18-15-6-2-5-14(15)16-10-12(19(22)23)7-8-17(16)21-18/h1-5,7-10,14-15,18,21H,6H2,(H,22,23) | PDB MMDB
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| Article PubMed
| 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371127
(CHEMBL244681)Show SMILES OC(=O)c1ccc(cc1)-n1cccc1CC1=NC(=O)NC1=O |t:17| Show InChI InChI=1S/C15H11N3O4/c19-13-12(16-15(22)17-13)8-11-2-1-7-18(11)10-5-3-9(4-6-10)14(20)21/h1-7H,8H2,(H,20,21)(H,17,19,22) | PDB MMDB
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371125
(CHEMBL244088)Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1ccccc1C(F)(F)F |w:13.12,9.9,8.18,c:11| Show InChI InChI=1S/C20H16F3NO2/c21-20(22,23)16-7-2-1-4-14(16)18-13-6-3-5-12(13)15-10-11(19(25)26)8-9-17(15)24-18/h1-5,7-10,12-13,18,24H,6H2,(H,25,26) | PDB MMDB
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| 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371131
(CHEMBL390874)Show InChI InChI=1S/C14H10BrNO2/c15-9-2-4-12-11(7-9)10-3-1-8(6-14(17)18)5-13(10)16-12/h1-5,7,16H,6H2,(H,17,18) | PDB MMDB
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| 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371118
(CHEMBL244693)Show InChI InChI=1S/C18H17NO4/c1-2-19-15-5-3-11(9-17(20)21)7-13(15)14-8-12(10-18(22)23)4-6-16(14)19/h3-8H,2,9-10H2,1H3,(H,20,21)(H,22,23) | PDB MMDB
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| 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371123
(CHEMBL244090)Show InChI InChI=1S/C12H11NO2S/c14-12(15)7-1-2-10-8(5-7)9-6-16-4-3-11(9)13-10/h1-2,5,13H,3-4,6H2,(H,14,15) | PDB MMDB
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| 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM38435
(9-ethyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazole-6-ca...)Show InChI InChI=1S/C15H15NO3/c1-2-16-12-7-6-9(15(18)19)8-11(12)10-4-3-5-13(17)14(10)16/h6-8H,2-5H2,1H3,(H,18,19) | PDB MMDB
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| 6.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371126
(CHEMBL438508)Show SMILES OC(=O)Cc1ccc(cc1)C1C(=S)NC2C=CSC2C1=O |w:14.14,10.10,18.18,c:16| Show InChI InChI=1S/C15H13NO3S2/c17-11(18)7-8-1-3-9(4-2-8)12-13(19)14-10(5-6-21-14)16-15(12)20/h1-6,10,12,14H,7H2,(H,16,20)(H,17,18) | PDB MMDB
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| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 8.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371130
(CHEMBL390873)Show SMILES OC(=O)c1ccc(cc1)C1Nc2c(F)cc(F)cc2C2C=CCC12 |w:19.21,23.24,9.9,c:22| Show InChI InChI=1S/C19H15F2NO2/c20-12-8-15-13-2-1-3-14(13)17(22-18(15)16(21)9-12)10-4-6-11(7-5-10)19(23)24/h1-2,4-9,13-14,17,22H,3H2,(H,23,24) | PDB MMDB
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| 9.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371124
(CHEMBL244694)Show InChI InChI=1S/C15H13NO2/c1-16-13-5-3-2-4-11(13)12-7-6-10(8-14(12)16)9-15(17)18/h2-8H,9H2,1H3,(H,17,18) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371121
(CHEMBL440951)Show InChI InChI=1S/C15H13F3N2O2/c16-15(17,18)13-11-3-1-2-4-12(11)20(19-13)10-7-5-9(6-8-10)14(21)22/h5-8H,1-4H2,(H,21,22) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371119
(CHEMBL244696)Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1cccnc1 |w:13.12,9.9,8.18,c:11| Show InChI InChI=1S/C18H16N2O2/c21-18(22)11-6-7-16-15(9-11)13-4-1-5-14(13)17(20-16)12-3-2-8-19-10-12/h1-4,6-10,13-14,17,20H,5H2,(H,21,22) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371117
(CHEMBL242146)Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccccc1F)c1ccccc1 |c:8| Show InChI InChI=1S/C19H17FN2O3/c20-15-9-5-4-8-14(15)17-12-16(13-6-2-1-3-7-13)21-22(17)18(23)10-11-19(24)25/h1-9,17H,10-12H2,(H,24,25) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371128
(CHEMBL390401)Show SMILES OC(=O)c1ccc2NC(C3CC=CC3c2c1)c1ccccc1 |w:13.12,9.9,8.18,c:11| Show InChI InChI=1S/C19H17NO2/c21-19(22)13-9-10-17-16(11-13)14-7-4-8-15(14)18(20-17)12-5-2-1-3-6-12/h1-7,9-11,14-15,18,20H,8H2,(H,21,22) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371129
(CHEMBL244328)Show InChI InChI=1S/C13H13NO2/c15-13(16)8-5-6-12-10(7-8)9-3-1-2-4-11(9)14-12/h5-7,14H,1-4H2,(H,15,16) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371116
(CHEMBL242148)Show SMILES Cn1c2ccc(cc2oc1=O)S(=O)(=O)N1CCC(CC1)C(O)=O Show InChI InChI=1S/C14H16N2O6S/c1-15-11-3-2-10(8-12(11)22-14(15)19)23(20,21)16-6-4-9(5-7-16)13(17)18/h2-3,8-9H,4-7H2,1H3,(H,17,18) | PDB MMDB
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| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |
Low molecular weight phosphotyrosine protein phosphatase
(Bos taurus) | BDBM50371122
(CHEMBL242363)Show SMILES OC(=O)CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)NCc1cccs1 Show InChI InChI=1S/C17H18N2O5S2/c20-16(5-6-17(21)22)19-8-7-12-10-14(3-4-15(12)19)26(23,24)18-11-13-2-1-9-25-13/h1-4,9-10,18H,5-8,11H2,(H,21,22) | PDB MMDB
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Research in Biomedicine (IRB)
Curated by ChEMBL
| Assay Description Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cells |
Eur J Med Chem 42: 1102-8 (2007)
Article DOI: 10.1016/j.ejmech.2007.01.017 BindingDB Entry DOI: 10.7270/Q27W6D1F |
More data for this Ligand-Target Pair | |