Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373848 (CHEMBL255779) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373845 (CHEMBL402939) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373844 (CHEMBL272948) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373847 (CHEMBL256605) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373851 (CHEMBL256431) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.59E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373846 (CHEMBL401537) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.97E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373843 (CHEMBL410400) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373849 (CHEMBL255988) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50373850 (CHEMBL404331) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens (Human)) | BDBM50231890 (2-((2-carboxyethyl)carbamoyl)-6-methyl-3-phenethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital Curated by ChEMBL | Assay Description Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay | Bioorg Med Chem Lett 18: 946-9 (2008) Article DOI: 10.1016/j.bmcl.2007.12.039 BindingDB Entry DOI: 10.7270/Q25D8SPT | |||||||||||
More data for this Ligand-Target Pair |