Compile Data Set for Download or QSAR

Found 11 hits of ic50 data for polymerid = 50006036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50537058 (CHEMBL4531719) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C)cc1 Show InChI InChI=1S/C20H23N5O/c1-3-4-8-17-14-25(24-23-17)18-12-10-16(11-13-18)21-20(26)22-19-9-6-5-7-15(19)2/h5-7,9-14H,3-4,8H2,1-2H3,(H2,21,22,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human DDX1 helicase activity				J Med Chem 62: 2333-2347 (2019) Article DOI: 10.1021/acs.jmedchem.8b01403 BindingDB Entry DOI: 10.7270/Q2X06BJK
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50537056 (CHEMBL4571759) Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N4O2S/c1-2-3-7-14-13-26(25-23-14)15-8-6-9-16(12-15)29(27,28)24-18-11-5-4-10-17(18)19(20,21)22/h4-6,8-13,24H,2-3,7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human DDX1 helicase activity				J Med Chem 62: 2333-2347 (2019) Article DOI: 10.1021/acs.jmedchem.8b01403 BindingDB Entry DOI: 10.7270/Q2X06BJK
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50537055 (CHEMBL4591917) Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1cccc2cnccc12 Show InChI InChI=1S/C21H21N5O2S/c1-2-3-7-17-15-26(25-23-17)18-8-5-9-19(13-18)29(27,28)24-21-10-4-6-16-14-22-12-11-20(16)21/h4-6,8-15,24H,2-3,7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human DDX1 helicase activity				J Med Chem 62: 2333-2347 (2019) Article DOI: 10.1021/acs.jmedchem.8b01403 BindingDB Entry DOI: 10.7270/Q2X06BJK
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50537057 (CHEMBL4551611) Show SMILES Oc1ccccc1NS(=O)(=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C12H10N2O5S/c15-12-7-2-1-6-11(12)13-20(18,19)10-5-3-4-9(8-10)14(16)17/h1-8,13,15H	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human DDX1 helicase activity				J Med Chem 62: 2333-2347 (2019) Article DOI: 10.1021/acs.jmedchem.8b01403 BindingDB Entry DOI: 10.7270/Q2X06BJK
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50379304 (CHEMBL2011805) Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccccc2[nH]1)c1cc2ccccc2o1 Show InChI InChI=1S/C22H15N3O2/c26-22(20-13-15-5-1-4-8-19(15)27-20)23-16-11-9-14(10-12-16)21-24-17-6-2-3-7-18(17)25-21/h1-13H,(H,23,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50379306 (CHEMBL2011806) Show SMILES Cc1[nH]c2ccccc2c1C1=CC(=NN=C(C1)c1ccccc1)c1ccccc1 |c:14,16,t:12| Show InChI InChI=1S/C26H21N3/c1-18-26(22-14-8-9-15-23(22)27-18)21-16-24(19-10-4-2-5-11-19)28-29-25(17-21)20-12-6-3-7-13-20/h2-16,27H,17H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50379303 (CHEMBL2011804) Show SMILES Cc1ccccc1NC(=O)Nc1cccc(NC(=O)Nc2ccccc2C)c1 Show InChI InChI=1S/C22H22N4O2/c1-15-8-3-5-12-19(15)25-21(27)23-17-10-7-11-18(14-17)24-22(28)26-20-13-6-4-9-16(20)2/h3-14H,1-2H3,(H2,23,25,27)(H2,24,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50379301 (CHEMBL2011809) Show SMILES Nc1cccc(NC(=O)Nc2cccc(N)c2)c1 Show InChI InChI=1S/C13H14N4O/c14-9-3-1-5-11(7-9)16-13(18)17-12-6-2-4-10(15)8-12/h1-8H,14-15H2,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM82820 (1,3-bis(3-nitrophenyl)urea | MLS000719904 | N,N...) Show SMILES [O-][N+](=O)c1cccc(NC(=O)Nc2cccc(c2)[N+]([O-])=O)c1 Show InChI InChI=1S/C13H10N4O5/c18-13(14-9-3-1-5-11(7-9)16(19)20)15-10-4-2-6-12(8-10)17(21)22/h1-8H,(H2,14,15,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50379302 (CHEMBL2011807) Show SMILES Cc1ccccc1NC(=O)Nc1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C14H13N3O3/c1-10-5-2-3-8-13(10)16-14(18)15-11-6-4-7-12(9-11)17(19)20/h2-9H,1H3,(H2,15,16,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DDX1 (Homo sapiens (Human))	BDBM50379305 (CHEMBL2011808) Show SMILES Cc1ccccc1NC(=O)Nc1cccc(N)c1 Show InChI InChI=1S/C14H15N3O/c1-10-5-2-3-8-13(10)17-14(18)16-12-7-4-6-11(15)9-12/h2-9H,15H2,1H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant DDX1 helicase activity expressed in Escherichia coli assessed as conversion of a 6-FAM-labeled double stranded RNA in...				Bioorg Med Chem Lett 22: 2094-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.135 BindingDB Entry DOI: 10.7270/Q2930V51
					More data for this Ligand-Target Pair