Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503445 (CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5RDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503445 (CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching method | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503445 (CHEMBL4445544 | US11274074, Example 1 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of ANO1 (unknown origin) expressed in FRT cells assessed as reduction in ATP-induced chloride current after 20 mins by electrophysiologica... | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50594075 (CHEMBL5186789) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50594073 (CHEMBL5206041) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239459 (CHEMBL4074929) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239459 (CHEMBL4074929) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239459 (CHEMBL4074929) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ANO1 channel (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112688 BindingDB Entry DOI: 10.7270/Q2N58R1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ANO1 channel expressed in HEK293 cells incubated for 10 mins by FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112688 BindingDB Entry DOI: 10.7270/Q2N58R1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ANO1 expressed in FRT cells assessed as inhibition of ATP-induced channel current treated 20 mins prior to ATP challenge and meas... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112688 BindingDB Entry DOI: 10.7270/Q2N58R1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of ANO1 (unknown origin) expressed in FRT cells assessed as reduction in ATP-induced chloride current after 20 mins by electrophysiologica... | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 20 mins followed by ... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239467 (CHEMBL4086165) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of TMEM16A (unknown origin) expressed in Xenopus laevis oocytes at -60 mV holding potential by voltage-clamp assay | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239459 (CHEMBL4074929) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5RDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching method | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239465 (CHEMBL4080525 | US11274074, Control [Ani9]) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239433 (CHEMBL3134585) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239428 (CHEMBL4104024) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239446 (CHEMBL4069503) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239457 (CHEMBL4071143) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503455 (CHEMBL4448175 | US11274074, Example 5 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5RDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503455 (CHEMBL4448175 | US11274074, Example 5 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching method | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239447 (CHEMBL4090522) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239461 (CHEMBL4074900) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239470 (CHEMBL4095338) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239457 (CHEMBL4071143) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239426 (CHEMBL1444023) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50594059 (CHEMBL5186589) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239433 (CHEMBL3134585) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503439 (CHEMBL4515829 | US11274074, Example 6 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5RDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503439 (CHEMBL4515829 | US11274074, Example 6 [Chemical Fo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching method | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239438 (CHEMBL4099581) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239475 (CHEMBL4082703) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239469 (CHEMBL4091961) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239458 (CHEMBL4095365) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239426 (CHEMBL1444023) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50075050 (Alinia | Nitazoxanide | PH-5776) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 424 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239463 (CHEMBL4087641) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomes | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239448 (CHEMBL4080209) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239464 (CHEMBL4085154) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239428 (CHEMBL4104024) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239439 (CHEMBL4083154) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239430 (CHEMBL4096263) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239464 (CHEMBL4085154) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50594049 (CHEMBL5185767) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114413 BindingDB Entry DOI: 10.7270/Q2GX4GK6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239462 (CHEMBL4066286) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50503453 (CHEMBL4577443) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University Curated by ChEMBL | Assay Description Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching method | Eur J Med Chem 160: 245-255 (2018) Article DOI: 10.1016/j.ejmech.2018.10.002 BindingDB Entry DOI: 10.7270/Q24T6NMB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Anoctamin-1 (Homo sapiens (Human)) | BDBM50239460 (CHEMBL4103095) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 925 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A... | J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 201 total ) | Next | Last >> |