Found 7 hits of ic50 data for polymerid = 50006129 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50391713
(CHEMBL2146956)Show InChI InChI=1S/C16H9N7S/c1-2-4-11-10(3-1)5-6-12(19-11)14-20-21-16-23(14)22-15(24-16)13-9-17-7-8-18-13/h1-9H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50391714
(CHEMBL2146957)Show SMILES SC1=NC(=O)C(S1)=Cc1cn(nc1-c1cccc(OCc2ccccc2Cl)c1)-c1ccccc1 |w:7.8,t:1| Show InChI InChI=1S/C26H18ClN3O2S2/c27-22-12-5-4-7-18(22)16-32-21-11-6-8-17(13-21)24-19(14-23-25(31)28-26(33)34-23)15-30(29-24)20-9-2-1-3-10-20/h1-15H,16H2,(H,28,31,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50391715
(CHEMBL2146960)Show SMILES Oc1ccc(C=c2c(=O)[nH]c3cc(=C)on3c2=N)cc1O |w:5.4| Show InChI InChI=1S/C14H11N3O4/c1-7-4-12-16-14(20)9(13(15)17(12)21-7)5-8-2-3-10(18)11(19)6-8/h2-6,15,18-19H,1H2,(H,16,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50237957
(4-(2-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-...)Show InChI InChI=1S/C15H11N3O4/c19-13-12(16-15(22)17-13)8-11-2-1-7-18(11)10-5-3-9(4-6-10)14(20)21/h1-8H,(H,20,21)(H2,16,17,19,22)/b12-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50391712
(CHEMBL2146959)Show SMILES [O-][N+](=O)c1ccccc1NC(=O)CSc1nnc(-c2ccco2)c(n1)-c1ccco1 Show InChI InChI=1S/C19H13N5O5S/c25-16(20-12-5-1-2-6-13(12)24(26)27)11-30-19-21-17(14-7-3-9-28-14)18(22-23-19)15-8-4-10-29-15/h1-10H,11H2,(H,20,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50387974
(CHEMBL2057830)Show SMILES Oc1ccc(cc1)C1=NN2C(S1)=NC(=O)\C(=C\c1ccc(O)c(O)c1)C2=N |c:13,t:8| Show InChI InChI=1S/C18H12N4O4S/c19-15-12(7-9-1-6-13(24)14(25)8-9)16(26)20-18-22(15)21-17(27-18)10-2-4-11(23)5-3-10/h1-8,19,23-25H/b12-7+,19-15? | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
Dual specificity protein phosphatase 4
(Homo sapiens (Human)) | BDBM50391711
(CHEMBL2146958)Show InChI InChI=1S/C16H10N2O3S/c19-12-6-5-9(7-13(12)20)8-14-15(21)18-11-4-2-1-3-10(11)17-16(18)22-14/h1-8,19-20H/b14-8- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sejong University
Curated by ChEMBL
| Assay Description
Inhibition of MKP2 |
Bioorg Med Chem Lett 22: 6333-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.081
BindingDB Entry DOI: 10.7270/Q2HT2QDC |
More data for this
Ligand-Target Pair | |
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