Compile Data Set for Download or QSAR

Found 6 hits of ic50 data for polymerid = 50006141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral ceramidase (Homo sapiens (Human))	BDBM50569052 (CHEMBL4866400) Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)NCCCCCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human ASAH2 using RBM14C24 fluorogenic substrate measured at pH 7.5				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50569052 (CHEMBL4866400) Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)NCCCCCC |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 fluorogenic substrate measured at pH 7.5 by fluorescence sp...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113296 BindingDB Entry DOI: 10.7270/Q2W66QJW
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50392471 (CHEMBL2152040) Show SMILES CCCCCCCCCCCCS(=O)(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O |r| Show InChI InChI=1S/C21H36N2O6S/c1-2-3-4-5-6-7-8-9-10-11-16-30(28,29)22-20(17-24)21(25)18-12-14-19(15-13-18)23(26)27/h12-15,20-22,24-25H,2-11,16-17H2,1H3/t20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Humboldt Universit£t zu Berlin Curated by ChEMBL					Assay Description Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce...				Bioorg Med Chem 20: 6162-70 (2012) Article DOI: 10.1016/j.bmc.2012.08.031 BindingDB Entry DOI: 10.7270/Q29Z960Z
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50392472 (CHEMBL408217) Show SMILES CCCCCCCCCCCCCC(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O |r| Show InChI InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Humboldt Universit£t zu Berlin Curated by ChEMBL					Assay Description Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce...				Bioorg Med Chem 20: 6162-70 (2012) Article DOI: 10.1016/j.bmc.2012.08.031 BindingDB Entry DOI: 10.7270/Q29Z960Z
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50428951 (CHEMBL2333179) Show SMILES C[C@@H](NC(=O)CCCCCCCCCCCN(C)C)[C@@H](O)c1ccccc1 |r| Show InChI InChI=1S/C23H40N2O2/c1-20(23(27)21-16-12-11-13-17-21)24-22(26)18-14-9-7-5-4-6-8-10-15-19-25(2)3/h11-13,16-17,20,23,27H,4-10,14-15,18-19H2,1-3H3,(H,24,26)/t20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Humboldt Universit£t zu Berlin Curated by ChEMBL					Assay Description Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assay				Bioorg Med Chem 21: 874-82 (2013) Article DOI: 10.1016/j.bmc.2012.12.014 BindingDB Entry DOI: 10.7270/Q29Z9673
					More data for this Ligand-Target Pair
Neutral ceramidase (Homo sapiens (Human))	BDBM50392472 (CHEMBL408217) Show SMILES CCCCCCCCCCCCCC(=O)N[C@H](CO)[C@H](O)c1ccc(cc1)[N+]([O-])=O |r| Show InChI InChI=1S/C23H38N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22(27)24-21(18-26)23(28)19-14-16-20(17-15-19)25(29)30/h14-17,21,23,26,28H,2-13,18H2,1H3,(H,24,27)/t21-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Humboldt Universit£t zu Berlin Curated by ChEMBL					Assay Description Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assay				Bioorg Med Chem 21: 874-82 (2013) Article DOI: 10.1016/j.bmc.2012.12.014 BindingDB Entry DOI: 10.7270/Q29Z9673
					More data for this Ligand-Target Pair