Compile Data Set for Download or QSAR

Found 56 hits of kd data for polymerid = 50006195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249571 (CHEMBL4101927 | US10729695, Compound CB-6) Show SMILES COc1cc(NC(C)=O)c(Cl)cc1C(=O)Nc1nccs1 Show InChI InChI=1S/C13H12ClN3O3S/c1-7(18)16-10-6-11(20-2)8(5-9(10)14)12(19)17-13-15-3-4-21-13/h3-6H,1-2H3,(H,16,18)(H,15,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249571 (CHEMBL4101927 | US10729695, Compound CB-6) Show SMILES COc1cc(NC(C)=O)c(Cl)cc1C(=O)Nc1nccs1 Show InChI InChI=1S/C13H12ClN3O3S/c1-7(18)16-10-6-11(20-2)8(5-9(10)14)12(19)17-13-15-3-4-21-13/h3-6H,1-2H3,(H,16,18)(H,15,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM95323 (4-[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-pyrim...) Show SMILES COc1ccccc1-c1cc(nc(n1)N1CCOCC1)C(F)(F)F Show InChI InChI=1S/C16H16F3N3O2/c1-23-13-5-3-2-4-11(13)12-10-14(16(17,18)19)21-15(20-12)22-6-8-24-9-7-22/h2-5,10H,6-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249579 (CHEMBL1477694 | US10729695, Compound CB-3) Show SMILES Cc1nc2ccccc2n1CC(O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C23H21N3O/c1-16-24-20-10-4-7-13-23(20)25(16)14-17(27)15-26-21-11-5-2-8-18(21)19-9-3-6-12-22(19)26/h2-13,17,27H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249574 (CHEMBL4077165 | US10729695, Compound CB-5) Show SMILES Oc1cccc(Nc2nc(cs2)-c2ccc(F)cc2F)c1 Show InChI InChI=1S/C15H10F2N2OS/c16-9-4-5-12(13(17)6-9)14-8-21-15(19-14)18-10-2-1-3-11(20)7-10/h1-8,20H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249574 (CHEMBL4077165 | US10729695, Compound CB-5) Show SMILES Oc1cccc(Nc2nc(cs2)-c2ccc(F)cc2F)c1 Show InChI InChI=1S/C15H10F2N2OS/c16-9-4-5-12(13(17)6-9)14-8-21-15(19-14)18-10-2-1-3-11(20)7-10/h1-8,20H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01571 BindingDB Entry DOI: 10.7270/Q25H7MBX
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249574 (CHEMBL4077165 | US10729695, Compound CB-5) Show SMILES Oc1cccc(Nc2nc(cs2)-c2ccc(F)cc2F)c1 Show InChI InChI=1S/C15H10F2N2OS/c16-9-4-5-12(13(17)6-9)14-8-21-15(19-14)18-10-2-1-3-11(20)7-10/h1-8,20H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM32273 (2,8-dimethyl-5,6-dihydrodipyrrolo[1,2-b:1',2'-e]py...) Show SMILES Cc1cc2-c3ccc(C)n3CCn2c1 Show InChI InChI=1S/C12H14N2/c1-9-7-12-11-4-3-10(2)14(11)6-5-13(12)8-9/h3-4,7-8H,5-6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453281 (US10729695, Compound CB-14) Show SMILES Oc1ccc(NCc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C13H12BrNO/c14-11-3-1-10(2-4-11)9-15-12-5-7-13(16)8-6-12/h1-8,15-16H,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249573 (CHEMBL4063929) Show SMILES COC(=O)c1cc(O)c(O)cc1NC(=O)C1Oc2ccccc2OC1C Show InChI InChI=1S/C18H17NO7/c1-9-16(26-15-6-4-3-5-14(15)25-9)17(22)19-11-8-13(21)12(20)7-10(11)18(23)24-2/h3-9,16,20-21H,1-2H3,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453279 (US10729695, Compound CB-8) Show SMILES COC(=O)c1cc(OC)c(OC)cc1NC(=O)C1Oc2ccccc2OC1C Show InChI InChI=1S/C20H21NO7/c1-11-18(28-15-8-6-5-7-14(15)27-11)19(22)21-13-10-17(25-3)16(24-2)9-12(13)20(23)26-4/h5-11,18H,1-4H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249577 (CHEMBL4072531 | US10729695, Compound CB-4) Show SMILES OC(Cn1ccc2ccccc12)Cn1cnc2ccccc12 Show InChI InChI=1S/C18H17N3O/c22-15(11-20-10-9-14-5-1-3-7-17(14)20)12-21-13-19-16-6-2-4-8-18(16)21/h1-10,13,15,22H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249577 (CHEMBL4072531 | US10729695, Compound CB-4) Show SMILES OC(Cn1ccc2ccccc12)Cn1cnc2ccccc12 Show InChI InChI=1S/C18H17N3O/c22-15(11-20-10-9-14-5-1-3-7-17(14)20)12-21-13-19-16-6-2-4-8-18(16)21/h1-10,13,15,22H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249575 (CHEMBL4100986 | US10729695, Compound CB-10) Show SMILES CC(C)CCC1C(C)=NN(C1=O)c1nc2ccccc2[nH]1 |c:7| Show InChI InChI=1S/C16H20N4O/c1-10(2)8-9-12-11(3)19-20(15(12)21)16-17-13-6-4-5-7-14(13)18-16/h4-7,10,12H,8-9H2,1-3H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249575 (CHEMBL4100986 | US10729695, Compound CB-10) Show SMILES CC(C)CCC1C(C)=NN(C1=O)c1nc2ccccc2[nH]1 |c:7| Show InChI InChI=1S/C16H20N4O/c1-10(2)8-9-12-11(3)19-20(15(12)21)16-17-13-6-4-5-7-14(13)18-16/h4-7,10,12H,8-9H2,1-3H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249576 (CHEMBL4075539 | US10729695, Compound CD-6) Show SMILES Cn1c2ccccc2n(CC(O)Cn2c3ccccc3c3ccccc23)c1=O Show InChI InChI=1S/C23H21N3O2/c1-24-21-12-6-7-13-22(21)26(23(24)28)15-16(27)14-25-19-10-4-2-8-17(19)18-9-3-5-11-20(18)25/h2-13,16,27H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249572 (CHEMBL1463447 | US10729695, Compound CB-1) Show SMILES COc1cc(SC)ccc1C(=O)Nc1cccc(C)n1 Show InChI InChI=1S/C15H16N2O2S/c1-10-5-4-6-14(16-10)17-15(18)12-8-7-11(20-3)9-13(12)19-2/h4-9H,1-3H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	US Patent	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249576 (CHEMBL4075539 | US10729695, Compound CD-6) Show SMILES Cn1c2ccccc2n(CC(O)Cn2c3ccccc3c3ccccc23)c1=O Show InChI InChI=1S/C23H21N3O2/c1-24-21-12-6-7-13-22(21)26(23(24)28)15-16(27)14-25-19-10-4-2-8-17(19)18-9-3-5-11-20(18)25/h2-13,16,27H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249572 (CHEMBL1463447 | US10729695, Compound CB-1) Show SMILES COc1cc(SC)ccc1C(=O)Nc1cccc(C)n1 Show InChI InChI=1S/C15H16N2O2S/c1-10-5-4-6-14(16-10)17-15(18)12-8-7-11(20-3)9-13(12)19-2/h4-9H,1-3H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453285 (US10729695, Compound CB-2) Show SMILES FC(F)(F)c1cc(=O)oc2cc(OCC=C)ccc12 Show InChI InChI=1S/C13H9F3O3/c1-2-5-18-8-3-4-9-10(13(14,15)16)7-12(17)19-11(9)6-8/h2-4,6-7H,1,5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM582522 (US11524942, Compound M5) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2O)cc1)-c1ccc(OCCCN(CC)CC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM582526 (US11524942, Compound M6) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)c(O)c2)cc1)-c1ccc(OCCCN(CC)CC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249580 (Azeliragon | PF-04494700 | TTP448 | US11524942, Co...) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCCN(CC)CC)cc1 Show InChI InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249580 (Azeliragon | PF-04494700 | TTP448 | US11524942, Co...) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCCN(CC)CC)cc1 Show InChI InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114347 BindingDB Entry DOI: 10.7270/Q2PG1WTJ
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249570 (CHEMBL4066660) Show SMILES Fc1ccc(cc1)C(=O)N(Cc1ccccc1)C1CCCCC1 Show InChI InChI=1S/C20H22FNO/c21-18-13-11-17(12-14-18)20(23)22(19-9-5-2-6-10-19)15-16-7-3-1-4-8-16/h1,3-4,7-8,11-14,19H,2,5-6,9-10,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01571 BindingDB Entry DOI: 10.7270/Q25H7MBX
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249570 (CHEMBL4066660) Show SMILES Fc1ccc(cc1)C(=O)N(Cc1ccccc1)C1CCCCC1 Show InChI InChI=1S/C20H22FNO/c21-18-13-11-17(12-14-18)20(23)22(19-9-5-2-6-10-19)15-16-7-3-1-4-8-16/h1,3-4,7-8,11-14,19H,2,5-6,9-10,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Binding affinity to human RAGE domain V by autoradiography				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249579 (CHEMBL1477694 | US10729695, Compound CB-3) Show SMILES Cc1nc2ccccc2n1CC(O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C23H21N3O/c1-16-24-20-10-4-7-13-23(20)25(16)14-17(27)15-26-21-11-5-2-8-18(21)19-9-3-6-12-22(19)26/h2-13,17,27H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM582520 (US11524942, Compound M2) Show SMILES CCCCc1nc(cn1Cc1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCCNCC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	22.3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249566 (CHEMBL4085254) Show SMILES CC1NC(NCCC[C@H](N)C(O)=O)=NC1=O |r,c:12| Show InChI InChI=1S/C9H16N4O3/c1-5-7(14)13-9(12-5)11-4-2-3-6(10)8(15)16/h5-6H,2-4,10H2,1H3,(H,15,16)(H2,11,12,13,14)/t5?,6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Binding affinity to human C-terminal His-tagged RAGE domain V (24 to 125 residues) expressed in Escherichia coli BL21(DE3) by tryptophan fluorescence...				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249582 (CHEMBL1547178 | US10729695, Compound CB-13) Show SMILES Cc1c(Cl)cccc1NC(=O)CNC(=O)c1ccccc1F Show InChI InChI=1S/C16H14ClFN2O2/c1-10-12(17)6-4-8-14(10)20-15(21)9-19-16(22)11-5-2-3-7-13(11)18/h2-8H,9H2,1H3,(H,19,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of CML binding to RAGE (unknown origin) by ELISA				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM26115 (CHEMBL286204 | Quinolinate | Quinolinic acid | pyr...) Show SMILES OC(=O)c1cccnc1C(O)=O Show InChI InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Binding affinity to human His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration method				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453292 (US10729695, Compound CD-4) Show SMILES OC(Cn1ccnc1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C18H17N3O/c22-14(11-20-10-9-19-13-20)12-21-17-7-3-1-5-15(17)16-6-2-4-8-18(16)21/h1-10,13-14,22H,11-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453304 (US10729695, Compound CD-29) Show SMILES Cc1nccn1CC(O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C19H19N3O/c1-14-20-10-11-21(14)12-15(23)13-22-18-8-4-2-6-16(18)17-7-3-5-9-19(17)22/h2-11,15,23H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM582527 (US11524942, Compound M7) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCCO)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	99.8	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249582 (CHEMBL1547178 | US10729695, Compound CB-13) Show SMILES Cc1c(Cl)cccc1NC(=O)CNC(=O)c1ccccc1F Show InChI InChI=1S/C16H14ClFN2O2/c1-10-12(17)6-4-8-14(10)20-15(21)9-19-16(22)11-5-2-3-7-13(11)18/h2-8H,9H2,1H3,(H,19,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM582518 (US11524942, Compound M1) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCC(O)=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	219	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM582521 (US11524942, Compound M3) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	257	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3J4M
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50249580 (Azeliragon | PF-04494700 | TTP448 | US11524942, Co...) Show SMILES CCCCc1nc(cn1-c1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCCN(CC)CC)cc1 Show InChI InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
King's College London Curated by ChEMBL					Assay Description Inhibition of amyloid beta (1 to 42) binding to RAGE domain V (unknown origin) by fluorescence polarization assay				J Med Chem 60: 7213-7232 (2017) Article DOI: 10.1021/acs.jmedchem.7b00058 BindingDB Entry DOI: 10.7270/Q2KD21BP
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453288 (US10729695, Compound CB-9) Show SMILES CN(C(F)F)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C9H11F2NO2S/c1-7-3-5-8(6-4-7)15(13,14)12(2)9(10)11/h3-6,9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453303 (US10729695, Compound CD-28) Show SMILES OC(COc1ccccc1)Cn1cnc2ccccc12 Show InChI InChI=1S/C16H16N2O2/c19-13(11-20-14-6-2-1-3-7-14)10-18-12-17-15-8-4-5-9-16(15)18/h1-9,12-13,19H,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453302 (US10729695, Compound CD-20) Show SMILES CC(C)CCC1C(C)=NN(C1=O)c1nc2ccccc2s1 |c:7| Show InChI InChI=1S/C16H19N3OS/c1-10(2)8-9-12-11(3)18-19(15(12)20)16-17-13-6-4-5-7-14(13)21-16/h4-7,10,12H,8-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453301 (US10729695, Compound CD-19) Show SMILES OC(COc1ccccc1C(O)=O)Cn1cnc2ccccc12 Show InChI InChI=1S/C17H16N2O4/c20-12(9-19-11-18-14-6-2-3-7-15(14)19)10-23-16-8-4-1-5-13(16)17(21)22/h1-8,11-12,20H,9-10H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453300 (US10729695, Compound CD-18) Show SMILES OC(CN(c1ccccc1)c1ccccc1)Cn1cnc2ccccc12 Show InChI InChI=1S/C22H21N3O/c26-20(15-24-17-23-21-13-7-8-14-22(21)24)16-25(18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-14,17,20,26H,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453299 (US10729695, Compound CD-16) Show SMILES OC(COc1cccc2ccccc12)Cn1cnc2ccccc12 Show InChI InChI=1S/C20H18N2O2/c23-16(12-22-14-21-18-9-3-4-10-19(18)22)13-24-20-11-5-7-15-6-1-2-8-17(15)20/h1-11,14,16,23H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453298 (US10729695, Compound CD-14) Show SMILES OC(COCc1ccccc1)Cn1cnc2ccccc12 Show InChI InChI=1S/C17H18N2O2/c20-15(12-21-11-14-6-2-1-3-7-14)10-19-13-18-16-8-4-5-9-17(16)19/h1-9,13,15,20H,10-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453297 (US10729695, Compound CD-12) Show SMILES OC(=O)COc1ccc2c(cc(=O)oc2c1)C(F)(F)F Show InChI InChI=1S/C12H7F3O5/c13-12(14,15)8-4-11(18)20-9-3-6(1-2-7(8)9)19-5-10(16)17/h1-4H,5H2,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453296 (US10729695, Compound CD-8) Show SMILES OC(COc1ccc(cc1)C#N)Cn1cnc2ccccc12 Show InChI InChI=1S/C17H15N3O2/c18-9-13-5-7-15(8-6-13)22-11-14(21)10-20-12-19-16-3-1-2-4-17(16)20/h1-8,12,14,21H,10-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453295 (US10729695, Compound CD-7) Show SMILES CN(CC(O)Cn1cnc2ccccc12)Cc1ccccc1 Show InChI InChI=1S/C18H21N3O/c1-20(11-15-7-3-2-4-8-15)12-16(22)13-21-14-19-17-9-5-6-10-18(17)21/h2-10,14,16,22H,11-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453282 (US10729695, Compound CD-1) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1nccs1 Show InChI InChI=1S/C12H11N3O2S/c1-8(16)14-10-4-2-9(3-5-10)11(17)15-12-13-6-7-18-12/h2-7H,1H3,(H,14,16)(H,13,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM453283 (US10729695, Compound CD-21) Show SMILES COc1ccccc1-c1cc(nc(NC2CCCCC2)n1)C(F)(F)F Show InChI InChI=1S/C18H20F3N3O/c1-25-15-10-6-5-9-13(15)14-11-16(18(19,20)21)24-17(23-14)22-12-7-3-2-4-8-12/h5-6,9-12H,2-4,7-8H2,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
The Research Foundation for the State University of New York; New York University US Patent					Assay Description Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...				US Patent US10729695 (2020) BindingDB Entry DOI: 10.7270/Q20868CW
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 56 total )  |  Next  |  Last  >>

Jump to: