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Compile Data Set for Download or QSAR

Found 10 hits of ki data for polymerid = 50006294   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM50420215
PNG
(CHEMBL339858)
Show SMILES CC(C)N1\C(=C/c2cc[n+](C(C)C)c3ccccc23)C=Cc2ccccc12 |c:21|
Show InChI InChI=1S/C25H27N2/c1-18(2)26-16-15-21(23-10-6-8-12-25(23)26)17-22-14-13-20-9-5-7-11-24(20)27(22)19(3)4/h5-19H,1-4H3/q+1
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15n/an/an/an/an/an/an/an/a



University of Heidelberg

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HEK293 cells


Nat Neurosci 1: 349-51 (1999)


Article DOI: 10.1038/1557
BindingDB Entry DOI: 10.7270/Q2FT8NB9
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM50014846
PNG
((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r|
Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
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120n/an/an/an/an/an/an/an/a



University of Heidelberg

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HEK293 cells


Nat Neurosci 1: 349-51 (1999)


Article DOI: 10.1038/1557
BindingDB Entry DOI: 10.7270/Q2FT8NB9
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM35229
PNG
(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Show SMILES CNCCCN1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3
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1.40E+4n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM50010859
PNG
(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Show SMILES CN(C)CCCN1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3
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4.20E+4n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM81945
PNG
(CAS_39484 | CHEMBL105891 | CHEMBL108926 | CHEMBL27...)
Show SMILES C[n+]1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C12H12N/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-10H,1H3/q+1
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5.40E+4n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM7966
PNG
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Show SMILES NCCc1cnc[nH]1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
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1.40E+5n/an/an/an/an/an/an/an/a



University of Heidelberg

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HEK293 cells


Mol Pharmacol 56: 1-10 (1999)


BindingDB Entry DOI: 10.7270/Q2KK9D21
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM50225285
PNG
(CHEBI:3757 | Catapres | Catapres-Tts-1 | Catapres-...)
Show SMILES Clc1cccc(Cl)c1NC1=NCCN1 |t:10|
Show InChI InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)
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3.73E+5n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM39344
PNG
(4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(N)cc1
Show InChI InChI=1S/C13H21N3O/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17)
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7.38E+5n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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1.37E+6n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair
Solute carrier family 22 member 3


(Homo sapiens (Human))
BDBM50420178
PNG
(GUANIDINE)
Show SMILES NC(N)=N
Show InChI InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
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6.20E+6n/an/an/an/an/an/an/an/a



Medical College of Georgia

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of MPP+ uptake in OCT3-expressing HRPE cells


Am J Physiol Renal Physiol 279: 449-58 (2000)


Article DOI: 10.1152/ajprenal.2000.279.3.f449
BindingDB Entry DOI: 10.7270/Q2708482
More data for this
Ligand-Target Pair