Compile Data Set for Download or QSAR

Found 20 hits of ic50 data for polymerid = 50006363,50006738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D-amino-acid oxidase (Mus musculus)	BDBM50431067 (CHEMBL2338797 | US10202399, Example 18 | US1046366...) Show SMILES Oc1cc(CCc2cccc(F)c2)n[nH]c1=O Show InChI InChI=1S/C12H11FN2O2/c13-9-3-1-2-8(6-9)4-5-10-7-11(16)12(17)15-14-10/h1-3,6-7H,4-5H2,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431074 (CHEMBL2338790 | US10463663, Example 27 | US1112982...) Show SMILES Oc1cc(CCc2ccc(Cl)cc2)n[nH]c1=O Show InChI InChI=1S/C12H11ClN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-2,4-5,7H,3,6H2,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431066 (CHEMBL2338798 | US10202399, Example 17 | US1046366...) Show SMILES Oc1cc(CCc2cccc(c2)C(F)(F)F)n[nH]c1=O Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)9-3-1-2-8(6-9)4-5-10-7-11(19)12(20)18-17-10/h1-3,6-7H,4-5H2,(H,17,19)(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431086 (CHEMBL2338800 | US10202399, Example 212 | US104636...) Show SMILES Oc1cc(CCc2ccc(F)cc2)n[nH]c1=O Show InChI InChI=1S/C12H11FN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-2,4-5,7H,3,6H2,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431077 (CHEMBL2338787 | US10202399, Example 48 | US1046366...) Show SMILES CC(c1ccccc1)c1cc(O)c(=O)[nH]n1 Show InChI InChI=1S/C12H12N2O2/c1-8(9-5-3-2-4-6-9)10-7-11(15)12(16)14-13-10/h2-8H,1H3,(H,13,15)(H,14,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431075 (CHEMBL2338789 | US10202399, Example 40 | US1046366...) Show SMILES Oc1cc(CCC2CCCCC2)n[nH]c1=O Show InChI InChI=1S/C12H18N2O2/c15-11-8-10(13-14-12(11)16)7-6-9-4-2-1-3-5-9/h8-9H,1-7H2,(H,13,15)(H,14,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431078 (CHEMBL2338786 | US10463663, Example 1 | US11129828...) Show SMILES Oc1cc(CCc2ccccc2)n[nH]c1=O Show InChI InChI=1S/C12H12N2O2/c15-11-8-10(13-14-12(11)16)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,13,15)(H,14,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431084 (CHEMBL2338802 | US10202399, Example 14) Show SMILES COc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1 Show InChI InChI=1S/C13H14N2O3/c1-18-11-6-3-9(4-7-11)2-5-10-8-12(16)13(17)15-14-10/h3-4,6-8H,2,5H2,1H3,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431069 (CHEMBL2338795 | US10202399, Example 27 | US1046366...) Show SMILES Oc1cc(CCc2ccccc2F)n[nH]c1=O Show InChI InChI=1S/C12H11FN2O2/c13-10-4-2-1-3-8(10)5-6-9-7-11(16)12(17)15-14-9/h1-4,7H,5-6H2,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431083 (CHEMBL2338803 | US10202399, Example 24 | US1046366...) Show SMILES Oc1cc(CCc2cc(F)cc(F)c2)n[nH]c1=O Show InChI InChI=1S/C12H10F2N2O2/c13-8-3-7(4-9(14)5-8)1-2-10-6-11(17)12(18)16-15-10/h3-6H,1-2H2,(H,15,17)(H,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431065 (CHEMBL2338799 | US10202399, Example 16) Show SMILES COc1cccc(CCc2cc(O)c(=O)[nH]n2)c1 Show InChI InChI=1S/C13H14N2O3/c1-18-11-4-2-3-9(7-11)5-6-10-8-12(16)13(17)15-14-10/h2-4,7-8H,5-6H2,1H3,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431070 (CHEMBL2338794) Show SMILES Oc1cc(COc2ccccc2)n[nH]c1=O Show InChI InChI=1S/C11H10N2O3/c14-10-6-8(12-13-11(10)15)7-16-9-4-2-1-3-5-9/h1-6H,7H2,(H,12,14)(H,13,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431085 (CHEMBL2338801 | US10202399, Example 12 | US1046366...) Show SMILES Oc1cc(CCc2ccc(cc2)C(F)(F)F)n[nH]c1=O Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)9-4-1-8(2-5-9)3-6-10-7-11(19)12(20)18-17-10/h1-2,4-5,7H,3,6H2,(H,17,19)(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431068 (CHEMBL2338796 | US10202399, Example 30 | US1046366...) Show SMILES Oc1cc(CCc2ccccc2C(F)(F)F)n[nH]c1=O Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)10-4-2-1-3-8(10)5-6-9-7-11(19)12(20)18-17-9/h1-4,7H,5-6H2,(H,17,19)(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431081 (CHEMBL2338805 | US10202399, Example 23) Show SMILES COc1cc(CCc2cc(O)c(=O)[nH]n2)cc(OC)c1 Show InChI InChI=1S/C14H16N2O4/c1-19-11-5-9(6-12(8-11)20-2)3-4-10-7-13(17)14(18)16-15-10/h5-8H,3-4H2,1-2H3,(H,15,17)(H,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431073 (CHEMBL2338791) Show SMILES Oc1cc(C=Cc2ccc(Cl)cc2)n[nH]c1=O |w:4.3| Show InChI InChI=1S/C12H9ClN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-7H,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431076 (CHEMBL2338788 | US10202399, Example 53 | US9212147...) Show SMILES Oc1cc(CCCc2ccccc2)n[nH]c1=O Show InChI InChI=1S/C13H14N2O2/c16-12-9-11(14-15-13(12)17)8-4-7-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,14,16)(H,15,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	426	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431082 (CHEMBL2338804 | US10202399, Example 19 | US1046366...) Show SMILES Oc1cc(CCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)n[nH]c1=O Show InChI InChI=1S/C14H10F6N2O2/c15-13(16,17)8-3-7(4-9(5-8)14(18,19)20)1-2-10-6-11(23)12(24)22-21-10/h3-6H,1-2H2,(H,21,23)(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM50431071 (CHEMBL2338793) Show SMILES CC(C)(C)CCc1cc(O)c(=O)[nH]n1 Show InChI InChI=1S/C10H16N2O2/c1-10(2,3)5-4-7-6-8(13)9(14)12-11-7/h6H,4-5H2,1-3H3,(H,11,13)(H,12,14)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Mus musculus)	BDBM337635 (6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...) Show SMILES Oc1cc(n[nH]c1=O)C1CCCCC1 Show InChI InChI=1S/C10H14N2O2/c13-9-6-8(11-12-10(9)14)7-4-2-1-3-5-7/h6-7H,1-5H2,(H,11,13)(H,12,14)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis				J Med Chem 56: 3582-92 (2013) Article DOI: 10.1021/jm400095b BindingDB Entry DOI: 10.7270/Q2HT2QPZ
					More data for this Ligand-Target Pair