Compile Data Set for Download or QSAR

Found 41 hits of ic50 data for polymerid = 50006380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM50499822 (CHEMBL3740897) Show SMILES C[C@H]1Cn2c(CN1C(=O)c1cccc(c1)C(F)(F)c1n[nH]c(=O)c3ccccc13)nnc2C(C)(F)F |r| Show InChI InChI=1S/C24H20F4N6O2/c1-13-11-34-18(29-32-22(34)23(2,25)26)12-33(13)21(36)14-6-5-7-15(10-14)24(27,28)19-16-8-3-4-9-17(16)20(35)31-30-19/h3-10,13H,11-12H2,1-2H3,(H,31,35)/t13-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...				Bioorg Med Chem Lett 25: 5743-7 (2015) Article DOI: 10.1016/j.bmcl.2015.10.079 BindingDB Entry DOI: 10.7270/Q2WH2T0J
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM50499821 (CHEMBL3740104) Show SMILES O=C(N1CCN(CC1)c1ncccc1C#N)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C26H22N6O2/c27-17-20-7-4-10-28-24(20)31-11-13-32(14-12-31)26(34)19-6-3-5-18(15-19)16-23-21-8-1-2-9-22(21)25(33)30-29-23/h1-10,15H,11-14,16H2,(H,30,33)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...				Bioorg Med Chem Lett 25: 5743-7 (2015) Article DOI: 10.1016/j.bmcl.2015.10.079 BindingDB Entry DOI: 10.7270/Q2WH2T0J
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM27566 (4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...) Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...				Bioorg Med Chem Lett 25: 5743-7 (2015) Article DOI: 10.1016/j.bmcl.2015.10.079 BindingDB Entry DOI: 10.7270/Q2WH2T0J
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553942 (US11325906, Example 6) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3Cl)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM50505333 (CHEMBL4437173) Show SMILES CC(C)(O)c1ccc(cc1)-c1nc2c(F)cc(F)cc2c(=O)[nH]1 Show InChI InChI=1S/C17H14F2N2O2/c1-17(2,23)10-5-3-9(4-6-10)15-20-14-12(16(22)21-15)7-11(18)8-13(14)19/h3-8,23H,1-2H3,(H,20,21,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Healthcare KGaA Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged recombinant human full length PARP6 expressed in Baculovirus infected Sf9 cells using biotinylated substrate afte...				J Med Chem 62: 7897-7909 (2019) Article DOI: 10.1021/acs.jmedchem.9b00656 BindingDB Entry DOI: 10.7270/Q2FJ2M28
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM50434157 (CHEMBL2381958 | US9340549, 78) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C27H23N3O3/c1-27(2)24(19-8-4-3-5-9-19)30(26(32)33-27)21-15-13-20(14-16-21)25(31)29-22-12-6-10-18-11-7-17-28-23(18)22/h3-17,24H,1-2H3,(H,29,31)/t24-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PARP6 (unknown origin) using histone as substrate after 1 hr by luminescence assay				J Med Chem 56: 4320-42 (2013) Article DOI: 10.1021/jm4000038 BindingDB Entry DOI: 10.7270/Q2QF8V74
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM50318567 (2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...) Show SMILES FC(F)(F)c1ccc(cc1)-c1nc2CCSCc2c(=O)[nH]1 Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Inhibition of PARP6 (unknown origin)				J Med Chem 56: 4497-508 (2013) Article DOI: 10.1021/jm400211f BindingDB Entry DOI: 10.7270/Q23R0V82
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM50434127 (CHEMBL2381633) Show SMILES Cc1cc(=O)[nH]c2cc(ccc12)-c1ccccc1F Show InChI InChI=1S/C16H12FNO/c1-10-8-16(19)18-15-9-11(6-7-12(10)15)13-4-2-3-5-14(13)17/h2-9H,1H3,(H,18,19)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Inhibition of PARP6 (unknown origin)				J Med Chem 56: 4497-508 (2013) Article DOI: 10.1021/jm400211f BindingDB Entry DOI: 10.7270/Q23R0V82
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553969 (US11325906, Example 32) Show SMILES CCNC(=O)c1ccc(cn1)N1CCN(Cc2cnc3cc(CC)c(=O)[nH]c3c2)CC1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553967 (US11325906, Example 30) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3C(F)(F)F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553948 (US11325906, Example 12) Show SMILES CCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553951 (US11325906, Example 14) Show SMILES CCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3Cl)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553939 (US11325906, Example 3) Show SMILES CCc1cc2cnc(CN3CCN(CC3)c3ccc(nc3Cl)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553966 (US11325906, Example 29) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3C(F)F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553938 (US11325906, Example 2) Show SMILES CCc1cc2cnc(CN3CCN(CC3)c3ccc(nc3F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553959 (US11325906, Example 22) Show SMILES CNC(=O)c1ccc(cn1)N1CCN(Cc2ccc3nc(c(=O)[nH]c3c2)C(C)(F)F)CC1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553944 (US11325906, Example 8) Show SMILES CCc1nc(ccc1N1CCN(Cc2ccc3nc(CC)c(=O)[nH]c3c2)CC1)C(=O)NC Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553940 (US11325906, Example 4) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553947 (US11325906, Example 11) Show SMILES CCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553943 (US11325906, Example 7) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3)C(N)=O)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553941 (US11325906, Example 5) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553946 (US11325906, Example 10) Show SMILES CCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3C(F)F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553968 (US11325906, Example 31) Show SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc(nc3C)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553955 (US11325906, Example 18) Show SMILES CCCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553956 (US11325906, Example 19) Show SMILES CCCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3Cl)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553950 (US11325906, Example 13) Show SMILES CCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3C)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553958 (US11325906, Example 21) Show SMILES CCc1nc2cc(F)c(CN3CCN(CC3)c3ccc(nc3F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553937 (US11325906, Example 1) Show SMILES CCc1cc2cnc(CN3CCN(CC3)c3ccc(nc3)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553945 (US11325906, Example 9) Show SMILES CCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3C(F)(F)F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM431646 (5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...) Show SMILES C[C@@H](COCCC(=O)N1CCN(CC1)c1ncc(cn1)C(F)(F)F)Nc1cn[nH]c(=O)c1C(F)(F)F |r| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00281 BindingDB Entry DOI: 10.7270/Q26D5Z03
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553954 (US11325906, Example 17) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(F)n1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553952 (US11325906, Example 15) Show SMILES CNC(=O)c1ccc(cn1)N1CCN(Cc2ccc3nc(c(=O)[nH]c3c2)C(F)(F)F)CC1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553963 (US11325906, Example 26) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(CCF)c(=O)[nH]c4c3)CC2)c(F)n1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553964 (US11325906, Example 27) Show SMILES CNC(=O)c1ccc(cn1)N1CCN(Cc2ccc3nc(CC(F)(F)F)c(=O)[nH]c3c2)CC1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553965 (US11325906, Example 28) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(CC(F)(F)F)c(=O)[nH]c4c3)CC2)c(F)n1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553961 (US11325906, Example 24) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(CC(F)F)c(=O)[nH]c4c3)CC2)c(F)n1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553957 (US11325906, Example 20) Show SMILES CCCc1nc2ccc(CN3CCN(CC3)c3ccc(nc3F)C(=O)NC)cc2[nH]c1=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM207624 (US10501467, Example 69 | US9260440, 69 | US9617273...) Show SMILES C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34 |r| Show InChI InChI=1S/C16H13FN4O/c1-16-3-2-4-21(16)7-11-13-12-9(15(22)20-19-11)5-8(17)6-10(12)18-14(13)16/h5-6H,2-4,7H2,1H3/t16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PARP-6 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01346 BindingDB Entry DOI: 10.7270/Q2474FGF
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553962 (US11325906, Example 25) Show SMILES CNC(=O)c1ccc(cn1)N1CCN(Cc2ccc3nc(CCF)c(=O)[nH]c3c2)CC1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553960 (US11325906, Example 23) Show SMILES CNC(=O)c1ccc(cn1)N1CCN(Cc2ccc3nc(CC(F)F)c(=O)[nH]c3c2)CC1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2348PKV
					More data for this Ligand-Target Pair