Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urea transporter 1 (Homo sapiens (Human)) | BDBM50394962 (CHEMBL1394231) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
San Francisco State University Curated by ChEMBL | Assay Description Inhibition of UT-B in human erythrocytes assessed as increase of hypotonic lysis | Bioorg Med Chem Lett 23: 3338-41 (2013) Article DOI: 10.1016/j.bmcl.2013.03.089 BindingDB Entry DOI: 10.7270/Q2CR5VRQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Urea transporter 1 (Homo sapiens (Human)) | BDBM50512227 (CHEMBL4454312) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of urea transporter B in human erythrocytes incubated for 6 mins by spectrophotometric analysis based erythrocyte lysis assay | Eur J Med Chem 172: 131-142 (2019) Article DOI: 10.1016/j.ejmech.2019.03.060 BindingDB Entry DOI: 10.7270/Q2C82DMK | |||||||||||
More data for this Ligand-Target Pair |